Evaluación del puntaje de sangrado “CRUSADE” como prueba diagnóstica para determinar sangrado mayor en pacientes con síndrome coronario agudo sin elevación del ST

Sudherwal, 2009, Baseline Risk of Major Bleeding in Non – ST – Segment Elevation Myocardial Infarction. The CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) Bleeding Score, Circulation, 119, 1873, 10.1161/CIRCULATIONAHA.108.828541 Anderson, 2009, Stopping the hemorrhage. A new baseline bleeding score brings us a step closer for patients with non – ST – elevation myocardial infarction, Circulation, 119, 1846, 10.1161/CIRCULATIONAHA.109.854281 Moscucci, 2003, Predictors of major bleeding in acute coronary syndromes: the Global Registry of Acute Coronary Events (GRACE), Eur Heart J, 24, 1815, 10.1016/S0195-668X(03)00485-8 Antman, 2000, The TIMI risk Score for unstable angina/Non ST elevation MI. A method for prognostication and therapeutic decision making, JAMA, 284, 835, 10.1001/jama.284.7.835 Boersma, 2000, Predictors of outcome in patients with acute coronary syndromes without persistent ST – segment elevation Results from an international trial of 9461 patients. The PURSUIT Investigators, Circulation, 101, 2557, 10.1161/01.CIR.101.22.2557 Anderson, 2007, J Am Coll Cardiol, 50, e1, 10.1016/j.jacc.2007.02.013 Bassand, 2007, The Task Force for the diagnosis and treatment of non–ST–segment elevation acute coronary syndromes of the European Society of Cardiology, Eur Heart J, 28, 1598, 10.1093/eurheartj/ehm161 Sobieraj – Teague, 2008, The risk of iatrogenic bleeding in acute coronary syndromes and long – term mortality, Current Opinion in Cardiology, 23, 327, 10.1097/HCO.0b013e3283021c5b Montalescot, 2006, Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention, N Engl J Med, 355, 1006, 10.1056/NEJMoa052711 Feit, 2007, Predictors and impact of major hemorrhage on mortality following percutaneous coronary intervention from the REPLACE – 2 Trail, Am J Cardiol, 100, 1364, 10.1016/j.amjcard.2007.06.026 Rao, 2005, Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes, Am J Cardiol, 96, 1200, 10.1016/j.amjcard.2005.06.056 Melloni, 2008, Management of acute coronary syndromes in patients with renal dysfunction, Curr Op Cardiol, 23, 320, 10.1097/HCO.0b013e3283021b08 Yusuf, 2006, Comparison of and enoxaparin in acute coronary syndromes: the OASIS – 5 randomized trial, N Engl J Med, 354, 1464, 10.1056/NEJMoa055443 Yusuf, 2006, Effects of fondaparinux on mortality and reinfarction in patients with acute ST – segment elevation myocardial infarction: the OASIS – 6 randomized trial, JAMA, 295, 1519, 10.1001/jama.295.13.joc60038 Mendoza, 2008, Guías Colombianas de Cardiología Síndrome coronario agudo sin elevación del ST, Rev Colomb Cardiol, 15, 141 Mehran, 2010, A risk score to predict bleeding in patients with acute coronary syndromes, J Am Coll Cardiol, 55, 2556, 10.1016/j.jacc.2009.09.076 Brinker, 2010, The score is in but is the final decision?, J Am Coll Cardiol, 55, 2567, 10.1016/j.jacc.2010.02.037 Stone, 2007, Bivalirudin in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a subgroup analysis from the Acute Catheterization and urgent intervention triage strategy (ACUITY) trial, Lancet, 369, 907, 10.1016/S0140-6736(07)60450-4 Stone, 2008, for the HORIZONS–AMI Trial Investigators Bivalirudin during primary PCI in acute myocardial infarction, N Engl J Med, 358, 2218, 10.1056/NEJMoa0708191 Rao, 2010, Hemorragia en pacientes con síndromes coronarios agudos: de un hallazgo molesto a un reto importante, Rev Esp Cardiol, 63, 1, 10.1016/S0300-8932(10)70001-4 Abu – Assi, 2010, Circulation, 121, 2419, 10.1161/CIRCULATIONAHA.109.925594 Mehran, 2011, Standardized Bleeding Definitions for Cardiovascular Clinical Trials. A Consensus report from the bleeding academic research consortium, Circulation, 123, 2736, 10.1161/CIRCULATIONAHA.110.009449 Steg, 2011, Bleeding in acute syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of Cardiology, Eur Heart J, 32, 1854, 10.1093/eurheartj/ehr204 Gutierrez, 2010, Incidencia, outcomes and management of bleeding in non – ST elevation acute coronary syndromes, Cleveland Clinic J Med, 77, 369, 10.3949/ccjm.77a.09142 Hamm, 2012, Guía de práctica clínica de la Sociedad Europea de Cardiología, para el manejo del síndrome coronario agudo en pacientes sin elevación persistente del segmento ST, Rev Esp Cardiol, 65, 173, 10.1016/j.recesp.2011.11.006 Wright, 2011, J Am Coll Cardiol, 57, 1, 10.1016/j.jacc.2011.02.009 Hicks, 2011, Bleeding academic research consortium consensus report The Food and Drug Administration Perpective, Circulation, 123, 2664, 10.1161/CIRCULATIONAHA.111.032433 Dauerman, 2011, Bleeding avoidance strategies. Consensus and Controversy, J Am Coll Cardiol, 58, 1, 10.1016/j.jacc.2011.02.039 Salam, 2003, Evolving role of bivalirudin in percutaneous coronary interventions; impact of the REPLACE -2 study, Expert Opin Investig Drugs, 12, 1027, 10.1517/13543784.12.6.1027