Estimation of bronchial tree zones involved in the formation of human forced expiratory wheezes
Tóm tắt
Forced expiratory wheezes (FEWs) are used for the diagnosis of bronchial obstruction; however, there is no clarity about the mechanisms and possible localization of their formation. The aim of the study was to clarify the sites of FEW formation at bronchial levels in different types of dynamic compression. The peak frequencies of the mid- (400–600 Hz) and high-frequency (more than 600 Hz) FEWs of the maximum power and the flow rate at the mouth were measured in a sample of 85 healthy male volunteers whose ages varied between 16 and 23 years. Strouhal coefficients were calculated for various bronchial tree levels according to Weibel’s morphometry. It is shown that, for FEWs formed by vortex shedding with Strouhal coefficients 0.2–0.3, the trend is to shift their formation zone to the proximal region with an increase in the degree of dynamic compression of the airways. For the most reliable estimates of dynamic compression, the main region of formation of mid-frequency FEWs is the area of exit of the intrathoracic portion of the trachea into its outer part and bifurcation of the trachea, while the most probable formation zone of early high-frequency FEWs is bifurcations of the primary bronchi and the trachea.
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