Estado actual de la investigación con células madre

Anales de Pediatría - Tập 59 - Trang 552-558 - 2003
C. Garrido Colino1
1Pediatra EAP. Panaderas II. Área IX. Fuenlabrada. Madrid. España

Tài liệu tham khảo

Mc Kay, 1997, Stem cells in the nevous system, Science, 276, 66, 10.1126/science.276.5309.66 Cordon, 1998, Reconstruction of the hematopoietic system after stem cell trasplantation, Cell Transplant, 7, 339, 10.1177/096368979800700401 Scheffler, 1999, Marrow-mindedness: A perspective on neuropoiesis, Trends Neurosci, 22, 348, 10.1016/S0166-2236(99)01416-2 Evans, 1981, Establishment in culture of pluripotential stem from mouse embryos, Nature, 291, 154, 10.1038/292154a0 Bradley, 1984, Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines, Nature, 309, 255, 10.1038/309255a0 Bishop, 2002, Embryonic stem cells, J Pathol, 197, 424, 10.1002/path.1154 Wobus, 1997, Retinoic acid accelerates embryonic stem cell-derived cardiac differentiation and enhances development of ventricular cardiomyocytes, J Mol Cell Cardiol, 29, 1525, 10.1006/jmcc.1997.0433 Doetschman, 1985, The in vitro development of blastocyst-derived embryonic stem cell lines: Formation of visceral yolk sac blood islands and myocardium, J Embryol Exp Morphol, 87, 27 Wiles, 1991, Multiple hematopoietic lineages develop from embryonic stem cells in culture, Development, 111, 259, 10.1242/dev.111.2.259 Lee, 2000, Efficient generation of midbrain and hinbrain neurons from mouse embryonic stem cells, Nat Biotechnol, 18, 675, 10.1038/76536 Maltsev, 1994, Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents, Circ Res, 75, 233, 10.1161/01.RES.75.2.233 Guan, 1999, Embryonic stem cell differentiation model: Cardiogenesis, myogenesisi, neurogenesis, epithelial and vascular smooth muscle cell differentiation in vitro, Cytotechnology, 30, 211, 10.1023/A:1008041420166 Wobus, 2001, Potential of embrionic stem cells, Molecular Aspects of Medicine, 22, 149, 10.1016/S0098-2997(01)00006-1 Blau, 2001, The Evolving concept of a stem cell: Entity or Function?, Cell, 105, 829, 10.1016/S0092-8674(01)00409-3 Malcon, 2002, An introdution to stem cells, J Pathology, 197, 419, 10.1002/path.1187 Ying, 2002, Changing potency by spontaneous fusion, Nature, 416, 540, 10.1038/nature729 Tereda, 2002, Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion, Nature, 416, 542, 10.1038/nature730 Clarke, 2000, Generalized potential of adult neural stem cells, Science, 288, 1660, 10.1126/science.288.5471.1660 Friedenstein, 1961, Osteogenic activity of trasplanted epithelium, Acta Anat, 45, 31, 10.1159/000141739 Reyes, 2001, Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells, Blood, 98, 2615, 10.1182/blood.V98.9.2615 Pittenger, 1999, Multilineage potential of adult human mesenchymal stem cells, Science, 284, 143, 10.1126/science.284.5411.143 Donald, 2002, Building a Consensus Regarding the Nature and Origin of Mesenchymal Stem Cells, J Cell Biochem, 7 Yuehua, 2002, Pluripotency of mesenchymal stem cells derived from adult marrow, Nature, 418, 41, 10.1038/nature00870 Reyes, 2002, Origin of endothelial progenitors in human postnatal bone marrow, J Clin Invest, 109, 337, 10.1172/JCI0214327 Burger, 2002, Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells, Blood, 100, 3527, 10.1182/blood.V100.10.3527 Condorelli, 2001, Cardiomyocytes induce endothelial cells to transdifferentiate into cardiac muscle: implications for myocardium regeneration, PNAS, 98, 10733, 10.1073/pnas.191217898 Yuri, 2003, Searching for Alternative Sources of Postnatal Human Mesenchymal Stem Cells: Candidate MSC-like Cells from Umbilical Cord, Stem Cells, 21, 105, 10.1634/stemcells.21-1-105 Bonnet, 2002, Haematopoietic stem cells, J Pathol, 197, 430, 10.1002/path.1153 Thomas, 1999, Purification of hematopoietic stem cells for further biological study, Methods, 17, 202, 10.1006/meth.1998.0731 Zanjani, 1999, Engraftment and multilineage expression of human bone marrow CD34– cells in vivo, Ann NY Acad Sci, 872, 220, 10.1111/j.1749-6632.1999.tb08467.x Bunting, 2002, ABC Transporters as Phenotypic Markers and Functional Regulators of Stem Cells, Stem Cells, 20, 11, 10.1002/stem.200011 Scharenberg, 2002, The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors, Blood, 99, 507, 10.1182/blood.V99.2.507 Hughes, 2002, Cardiac stem cells, J Pathol, 197, 468, 10.1002/path.1159 Orlic, 2001, Trasplanted adult bone marrow cells repair myocardial infarcts in mice, Ann N Y Acad Sci, 938, 221, 10.1111/j.1749-6632.2001.tb03592.x Orlic, 2001, Bone marrow cells regenerate infarcted myocardium, Nature, 410, 701, 10.1038/35070587 Jackson, 2001, Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells, J Clin Invest, 107, 1395, 10.1172/JCI12150 Orlic, 2001, Mobilized bone marrow cells repair the infarcted heart, improving function and survival, Proc Natl Acad Sci USA, 98, 10344, 10.1073/pnas.181177898 Eriksson, 1998, Neurogenesis in the adult humanhippocampus, Nat Med, 4, 1313, 10.1038/3305 Gage, 2000, Mammalian neural stem cells, Science, 287, 1433, 10.1126/science.287.5457.1433 Sánchez-Ramos, 1998, Differentiation of neuron-like cells from bone marrow stromal cells, Mov Disord, 13, 122 Sánchez-Ramos, 2000, Adult bone marrow stromal differentiate into neural cells in vitro, Exp Neurol, 164, 247, 10.1006/exnr.2000.7389 Reyes, 2001, Characterization of multipotent adult progenito cells, a subpopulation of mesenchymal stem cells, Ann N Y Acad Sci, 938, 231, 10.1111/j.1749-6632.2001.tb03593.x Deng, 2001, In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP, Biochem Biophys Res Commum, 282, 148, 10.1006/bbrc.2001.4570 Eglitis, 1997, Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice, Proc Natl Acad Sci USA, 94, 4080, 10.1073/pnas.94.8.4080 Brazelton, 2000, From marrow to brain: expression of neural phenotypes in adult mice, Science, 290, 1775, 10.1126/science.290.5497.1775 Li, 2001, Intracerebral trasplantation of bone marrow stromal cells in a 1-methyl-4 phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease, Neurosci Lett, 316, 67, 10.1016/S0304-3940(01)02384-9 Li, 2000, Intrastriatal trasplantation of bone marrownonhematopoietic cells improves functional recovery after stroke in adult mice, J Cereb Blood Flow Metab, 20, 1311, 10.1097/00004647-200009000-00006 Chen, 2000, Intracerebral of bone marrow with BDNF after MCAo in rat, Neuropharmacology, 39, 711, 10.1016/S0028-3908(00)00006-X Bonner-Weir, 2002, Pancreatic stem cells, J Pathol, 197, 519, 10.1002/path.1158 Zulewski, 2001, Multipotential nestinpositive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes, Diabetes, 50, 521, 10.2337/diabetes.50.3.521 Reddy, 1984, Induction and origin of hepatocytes in rat pancreas, J Cell Biol, 98, 2082, 10.1083/jcb.98.6.2082 Bonner-Weir, 2000, In vitro cultivation of human islets from expanded ductal tissue, Proc Natl Acad Sci USA, 97, 7999, 10.1073/pnas.97.14.7999 Brockenbrough, 1988, Discordance of exocrine and endocrine growth after 90 % pancreatectomy in rats, Diabetes, 37, 232, 10.2337/diab.37.2.232 Butler, 2003, Beta-cell deficit and increased beta-cell apoptosis in human with type 2 diabetes, Diabetes, 52, 102, 10.2337/diabetes.52.1.102 Theise, 2000, Derivationof hepatocytes from bone marrow cells in mice after radiation-induced myeloablation, Hepatology, 31, 234, 10.1002/hep.510310135 Alison, 2000, Hepatocytes from non-hepatic adult stem cells, Nature, 406, 257, 10.1038/35018642 Theise, 2000, Liver from bone marrow in humans, Hepatology, 32, 11, 10.1053/jhep.2000.9124 Kleeberger, 2002, High frequency of epithelial chimerism in liver tranplants demonstrated by microdissection and STR-analysis, Hepatology, 35, 110, 10.1053/jhep.2002.30275 Lagasse, 2000, Purified hematopoietic stem cells can differentiate into hepatocytes in vivo, Nature Med, 6, 1229, 10.1038/81326 Yokoo, 2001, Genetically modified bone marrow continuosly supplies antiinflammatory cells and suppresses renal injury in mouse Goodpasture syndrome, Blood, 98, 57, 10.1182/blood.V98.1.57 Cornacchia, 2001, Glomerulosclerosis is transmited by bone marrow-derived mesangial cell progenitors, J Clin Invest, 108, 1649, 10.1172/JCI200112916 Brittan, 2002, Gastrointestinal stem cells, J Pathol, 197, 492, 10.1002/path.1155 Krause, 2001, Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell, Cell, 105, 369, 10.1016/S0092-8674(01)00328-2 Kontoyiannis, 1999, Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies, Immunity, 10, 384, 10.1016/S1074-7613(00)80038-2 Targan, 1999, A Short –term study of chimeric monoclonal and mammary gland epithelium, Am J Pathol, 154, 29 Lipton, 1979, Developmental fate of skeletalmuscle satellite cells, Science, 205, 1292, 10.1126/science.472747 Seale, 2000, Pax-7 is required for the specificationof miogenic satellite cells, Cell, 102, 777, 10.1016/S0092-8674(00)00066-0 Feldman, 1992, Temporal appearance of satellite cells during myogenesis, Dev Biol, 153, 217, 10.1016/0012-1606(92)90107-R Beauchamp, 1999, Dynamic of myoblast trasplantation reveal a discrete minority of precursors with stem cell-like properties as the myogenic source, J Cell Biol, 144, 1113, 10.1083/jcb.144.6.1113 Beauchamp, 1997, A dual-marker system for quantitative studies of myoblast trasplantation in the mouse, Trasplantation, 63, 1794, 10.1097/00007890-199706270-00015 Ferrari, 1998, Muscle regeneration by bone marrow derived myogenic progenitors, Science, 279, 1528, 10.1126/science.279.5356.1528 Partridge, 1998, The fantastic voyage of muscle progenitor cells, Nature Med, 4, 554, 10.1038/nm0598-554 Gussoni, 1999, Dystrophin expression in the mdx mouse restored by stem cell trasplantation, Nature, 401, 390, 10.1038/43919 Danko, 1992, The frequency of revertants in mdx mouse genetic model for Duchenne muscular dystrophy, Pediatr Res, 32, 128, 10.1203/00006450-199207000-00025 Richard, 1996, Isolation and characterization of osteoblast precursor cells from human bone marrow, J Bone Miner Res, 11, 312, 10.1002/jbmr.5650110305 Kotton, 2001, Bone marrow derived cells as progenitors of lung alveolar epithelium, Development, 128, 5181, 10.1242/dev.128.24.5181 Nilsson, 1999, Cells capable of bone production engraft from whole bone marrow transplants in nonablated mice, J Exp Med, 189, 729, 10.1084/jem.189.4.729 Pereira, 1998, Marrow stromal cells, a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta, Proc Natl Acad Sci USA, 95, 1142, 10.1073/pnas.95.3.1142 Pereira, 1995, Cultured adherent cells from marrow can serve as long –lasting precursor cells for bone, cartilage and lung in irradiated mice, Proc Natl Acad Sci, 92, 4857, 10.1073/pnas.92.11.4857 Horwitz, 1999, Osteogenesis imperfecta calls for caution, Nature Med, 5, 466, 10.1038/8327 Horwitz, 1999, Trasplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta, Nature Med, 5, 309, 10.1038/6529