Establishment of immortalized Schwann cells from Sandhoff mice and corrective effect of recombinant human β-hexosaminidase A on the accumulated GM2 ganglioside

Journal of Human Genetics - Tập 50 Số 9 - Trang 460-467 - 2005
Mai Ohsawa1,2, Masaharu Kotani1,2, Youichi Tajima1,2, Daisuke Tsuji1,3, Yasuhiro Ishibashi1,3, Aya Kuroki1,3, Kohji Itoh1,3, Kazuhiko Watabe1,4, Kazunori Sango5, Shoji Yamanaka6, Hitoshi Sakuraba7,8
1CREST, JST, Kawaguchi, Japan
2Department of Clinical Genetics, The Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo 113-8613, Japan
3Department of Medicinal Biotechnology, Institute for Medicinal Resources, Graduate School of Pharmaceutical Sciences, The University of Tokushima, Tokushima, Japan.
4Department of Molecular Neuropathology, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Tokyo, Japan.
5Department of Developmental Morphology, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Tokyo, Japan
6Department of Pathology, School of Medicine, Yokohama City University, Yokohama, Japan
7CREST, JST, Kawaguchi, Japan. [email protected].
8Department of Clinical Genetics, The Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo, 113-8613, Japan. [email protected].

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