Established murine lupus nephritis does not respond to exogenous interleukin-1 receptor antagonist; a role for the endogenous molecule?

Immunopharmacology - Tập 30 - Trang 131-137 - 1995
Bryce A. Kiberd1, Andrew W. Stadnyk2,3
1Department of Medicine, Dalhousie University, Halifax, N.S., Canada.
2Department of Pediatrics, Dalhousie University, Halifax, N.S., Canada
3Department of Microbiology/Immunology, Dalhousie Uneversity, Halifax, N.S., Canada

Tài liệu tham khảo

Boswell, 1988, Increased tumor necrosis factor and IL-1β gene expression in kidneys of mice with lupus nephritis, J. Immunol., 141, 3050, 10.4049/jimmunol.141.9.3050 Brennan, 1989, Tumor necrosis factor and IL-1 in New Zealand Black/White mice, J. Immunol., 143, 3470, 10.4049/jimmunol.143.11.3470 Diamond, 1991, Glomerular tumor necrosis factor and interleukin 1 during acute aminonucleoside nephrosis, Lab. Invest., 64, 21 Dinarello, 1991, Interleukin-1 and interleukin-1 antagonism, Blood, 77, 1627, 10.1182/blood.V77.8.1627.1627 Dinarello, 1991, Blocking IL-1: interleukin 1 receptor antagonism in vivo and in vitro, Immunol. Today, 12, 404, 10.1016/0167-5699(91)90142-G Faherty, 1992, Failure of IL-1 receptor antagonism and monoclonal anti-IL-1 receptor antibody to inhibit antigen specific immune responses in vivo, J. Immunol., 148, 766, 10.4049/jimmunol.148.3.766 Finck, 1994, Interleukin 6 promotes murine lupus in NZB/NZW F1 mice, J. Clin. Invest., 94, 585, 10.1172/JCI117373 Finkelman, 1993, Anti-cytokine antibodies as carrier proteins, J. Immunol., 151, 1235, 10.4049/jimmunol.151.3.1235 Fischer, 1992, Interleukin-1 receptor blockade improves survival and hemo-dynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia, J. Clin. Invest., 89, 1551, 10.1172/JCI115748 Hahn, 1993, Overview of the pathogenesis of systemic lupus erythematosus, 65 Hannum, 1990, Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor, Nature, 343, 336, 10.1038/343336a0 Kiberd, 1991, Murine lupus nephritis, Lab. Invest., 65, 51 Kiberd, 1992, Interleukin-6 in murine lupus nephritis, J. Am. Soc. Nephrol., 3, 578 Kiberd, 1992, The functional and structural changes of the glomerulus throughout the course of murine lupus nephritis, J. Am. Soc. Nephrol., 3, 930, 10.1681/ASN.V34930 Kiberd, 1993, Effects of IL-6 blockage in murine lupus nephritis, J. Am. Soc. Nephrol., 4, 58, 10.1681/ASN.V4158 Lan, 1993, Suppression of experimental crescentic glomeru-lonephritis by the interleukin-1 receptor antagonist, Kidney Int., 43, 479, 10.1038/ki.1993.70 Lovett, 1983, Stimulation of rat mesangial cell proliferation by macrophage interleukin 1, J. Immunol., 131, 2830, 10.4049/jimmunol.131.6.2830 Matsumoto, 1989, Production of interleukin-1 in glomerular cultures from rats with nephrotoxic serum nephritis, Clin. Exp. Immunol., 75, 123 Mihara, 1991, Murine anti-human IL-6 monoclonal antibody prolongs the half life in circulating blood and thus prolongs the bioactivity of human IL-6 in mice, Immunology, 74, 55 Montinaro, 1992, Extrarenal cytokines modulate the glomerular response to IgA immune complexes, Kidney Int., 42, 341, 10.1038/ki.1992.295 Muegge, 1991, Cytokines and their cellular receptors, 6.2.1 Spurney, 1992, Thromboxane receptor blockade reduced renal injury in murine lupus nephritis, Kidney Int., 41, 973, 10.1038/ki.1992.149 Tam, 1994, Glomerular expression of interleukin-1 receptor antagonist and interleukin-1β genes in antibody-mediated glomerulonephritis, Am. J. Pathol., 145, 126 Tang, 1990, Age-associated increase in interleukin 6 in MRL/Ipr mice, Int. Immunol., 3, 74 Tang, 1994, Interleukin-1 receptor antagonist ameliorates experimental anti-glomemlar basement membrane antibody-associated glomerulonephritis, J. Clin. Invest., 93, 273, 10.1172/JCI116956 Tomosugi, 1989, Modulation of antibody-mediated glomerular injury in vivo by bacterial lipopolysaccharide, tumor necrosis factor and IL-1, J. Immunol., 142, 3083, 10.4049/jimmunol.142.9.3083 Wakabayashi, 1991, A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced septic shock, FASEB J., 5, 338, 10.1096/fasebj.5.3.1825816 Werber, 1987, The interleukin 1 gene is expressed by rat glomerular cells and is augmented in immune complex glomerulonephritis, J. Immunol., 138, 3207, 10.4049/jimmunol.138.10.3207 Wuthrich, 1990, Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis, Am. J. Pathol., 136, 441