Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease
Tóm tắt
Từ khóa
Tài liệu tham khảo
Clayburgh, 2004, A porous defense: the leaky epithelial barrier in intestinal disease, Lab Invest, 84, 282, 10.1038/labinvest.3700050
Hollander, 1988, Crohn's disease—a permeability disorder of the tight junction?, Gut, 29, 1621, 10.1136/gut.29.12.1621
Katz, 1989, Intestinal permeability in patients with Crohn's disease and their healthy relatives, Gastroenterology, 97, 927, 10.1016/0016-5085(89)91499-6
Ukabam, 1983, Abnormal small intestinal permeability to sugars in patients with Crohn's disease of the terminal ileum and colon, Digestion, 27, 70, 10.1159/000198932
Irvine, 2000, Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk, Gastroenterology, 119, 1740, 10.1053/gast.2000.20231
Wyatt, 1993, Intestinal permeability and the prediction of relapse in Crohn's disease, Lancet, 341, 1437, 10.1016/0140-6736(93)90882-H
Yacyshyn, 1995, CD45RO expression on circulating CD19+ B cells in Crohn's disease correlates with intestinal permeability, Gastroenterology, 108, 132, 10.1016/0016-5085(95)90017-9
Suenaert, 2002, Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease, Am J Gastroenterol, 97, 2000, 10.1111/j.1572-0241.2002.05914.x
Hiribarren, 1993, Effect of cytokines on the epithelial function of the human colon carcinoma cell line HT29 cl 19A, Gut, 34, 616, 10.1136/gut.34.5.616
Taylor, 1998, Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha, Gastroenterology, 114, 657, 10.1016/S0016-5085(98)70579-7
Zolotarevsky, 2002, A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease, Gastroenterology, 123, 163, 10.1053/gast.2002.34235
Clayburgh, 2005, Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo, J Clin Invest, 115, 2702, 10.1172/JCI24970
Turner, 1997, Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation, Am J Physiol, 273, C1378, 10.1152/ajpcell.1997.273.4.C1378
Scott, 2002, Intestinal infection with Giardia spp. reduces epithelial barrier function in a myosin light chain kinase-dependent fashion, Gastroenterology, 123, 1179, 10.1053/gast.2002.36002
Yuhan, 1997, Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability, Gastroenterology, 113, 1873, 10.1016/S0016-5085(97)70006-4
Wang, 2005, Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression, Am J Pathol, 166, 409, 10.1016/S0002-9440(10)62264-X
Ma, 2005, Mechanism of TNF-alpha modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression, Am J Physiol Gastrointest Liver Physiol, 288, G422, 10.1152/ajpgi.00412.2004
Clayburgh, 2004, A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability, J Biol Chem, 279, 55506, 10.1074/jbc.M408822200
Berglund, 2001, Regulation of human jejunal transmucosal resistance and MLC phosphorylation by Na+-glucose cotransport, Am J Physiol Gastrointest Liver Physiol, 281, G1487, 10.1152/ajpgi.2001.281.6.G1487
Graham, 2005, AP1-dependent transcriptional activation of myosin light chain kinase mediates IFNgamma- and TNFalpha-induced barrier dysfunction, FASEB J, 19
Micke, 2006, Biobanking of fresh frozen tissue: RNA is stable in non-fixed surgical specimens, Lab Invest, 86, 10.1038/labinvest.3700372
Prasad, 2005, Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells, Lab Invest, 85, 1139, 10.1038/labinvest.3700316
Heller, 2005, Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution, Gastroenterology, 129, 550, 10.1016/j.gastro.2005.05.002
Gitter, 2000, Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis, FASEB J, 14, 1749, 10.1096/fj.99-0898com
Musch, 2002, T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase, J Clin Invest, 110, 1739, 10.1172/JCI0215695
Bruewer, 2003, Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms, J Immunol, 171, 6164, 10.4049/jimmunol.171.11.6164
Ma, 1999, Ethanol modulation of intestinal epithelial tight junction barrier, Am J Physiol, 276, G965
Hollander, 1993, Permeability in Crohn's disease: altered barrier functions in healthy relatives?, Gastroenterology, 104, 1848, 10.1016/0016-5085(93)90668-3
Meddings, 1994, Intestinal permeability in patients with Crohn's disease, Gut, 35, 1675, 10.1136/gut.35.11.1675-b
Jenkins, 1988, Small bowel and colonic permeability to 51Cr-EDTA in patients with active inflammatory bowel disease, Clin Invest Med, 11, 151
Gitter, 2001, Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging, Gastroenterology, 121, 1320, 10.1053/gast.2001.29694
Jarnerot, 2005, Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study, Gastroenterology, 128, 1805, 10.1053/j.gastro.2005.03.003
Baert, 1999, Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis, Gastroenterology, 116, 22, 10.1016/S0016-5085(99)70224-6
D'Haens, 1999, Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: A European multicenter trial, Gastroenterology, 116, 1029, 10.1016/S0016-5085(99)70005-3