Epidermal Growth Factor and Hypoxia-induced Expression of CXC Chemokine Receptor 4 on Non-small Cell Lung Cancer Cells Is Regulated by the Phosphatidylinositol 3-Kinase/PTEN/AKT/Mammalian Target of Rapamycin Signaling Pathway and Activation of Hypoxia Inducible Factor-1α

Journal of Biological Chemistry - Tập 280 Số 23 - Trang 22473-22481 - 2005
Roderick J. Phillips1, Javier Mestas1, Mehrnaz Gharaee−Kermani1, Marie D. Burdick1, Antonio Sica2, John A. Belperio1, Michael P. Keane1, Robert M. Strieter3,1
1Division of Pulmonary and Critical Care Medicine
2Instituto di Ricerche Farmacologiche “Mario Negri,” 20157, Milan, Italy
3Departments of Pathology and Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095

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