Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by β3 integrin signaling

Manikandan Panchatcharam1, Sumitra Miriyala1, Fanmuyi Yang1, Michael Leitges2,3, Magdalena Chrzanowska-Wodnicka4, Lawrence A. Quilliam5, Paul Anaya1, Andrew J. Morris1, Susan S. Smyth1,6
1Division of Cardiovascular Medicine, The Gill Heart Institute, University of Kentucky, Lexington, KY 40536-0200, United States
2Biotechnology Centre of Oslo, University of Oslo, Oslo N-0317, Norway
3Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
4Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI 53201-2178, United States
5Department of Biochemistry and Molecular Biology, Indiana University School of Medicine and Walther Cancer Institute, Indianapolis, IN 46202-5122, United States
6Department of Veterans Affairs Medical Center, Lexington, KY 40511, United States