Enhanced Performance of Aloe vera-Incorporated Bacterial Cellulose/Polycaprolactone Composite Film for Wound Dressing Applications

Journal of Polymers and the Environment - Tập 30 - Trang 1151-1161 - 2021
Pornsuda Kotcharat1, Piyachat Chuysinuan2, Thanyaluck Thanyacharoen2, Supanna Techasakul2, Sarute Ummartyotin1
1Faculty of Science and Technology, Department of Materials and Textile Technology, Thammasat University, Pathumthani, Thailand
2Laboratory of Organic Synthesis, Chulabhorn Research Institute, Bangkok, Thailand

Tóm tắt

Recently, biopolymers have become a resource for the biomedical material field due to its biocompatibility and biodegradability. In this work, Aloe vera-loaded bacterial cellulose- and polycaprolactone -based composites were successfully prepared for wound dressing applications. The structural, morphological, thermal, swelling, and degradation properties were investigated. Result showed that the addition of Aloe vera resulted in a strong peak characteristic of hydroxyl groups and amide I by attenuated total reflectance-Fourier transform infrared analysis. Pores were present inside the composite structure and varied with the Aloe vera content. No crystallinity peak of Aloe vera was observed. Thermogravimetric analysis indicated a slight change in the thermal decomposition temperature and a loss of water molecules below 100 °C. The swelling and weight loss behaviour were remarkably changed when only 5% Aloe vera was loaded into the composite. Moreover, Aloe vera enhanced the toughness and elongation of the composite. All the composites exhibited a burst release profiles within 60 min. The MTT assay showed a concerningly low cell viability concerning the amount of Aloe vera loaded into the composite. Therefore, Aloe vera-loaded BC and PCL composites could be developed for wound dressing applications.

Tài liệu tham khảo

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