Endurance exercise training increases adipose tissue glucocorticoid exposure: adaptations that facilitate lipolysis

Andrews, 1999, Glucocorticoids and insulin resistance: old hormones, new targets, Clin Sci (Lond), 96, 513, 10.1042/CS19980388 White, 1997, 11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess, Endocr Rev, 18, 135, 10.1210/er.18.1.135 Masuzaki, 2001, A transgenic model of visceral obesity and the metabolic syndrome, Science, 294, 2166, 10.1126/science.1066285 Whorwood, 2001, Regulation of glucocorticoid receptor alpha and beta isoforms and type I 11beta-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: a key role in the pathogenesis of insulin resistance?, J Clin Endocrinol Metab, 86, 2296, 10.1210/jc.86.5.2296 Bujalska, 1999, Differentiation of adipose stromal cells: the roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase, Endocrinology, 140, 3188, 10.1210/en.140.7.3188 Desbriere, 2006, 11beta-Hydroxysteroid dehydrogenase type 1 mRNA is increased in both visceral and subcutaneous adipose tissue of obese patients, Obesity (Silver Spring), 14, 794, 10.1038/oby.2006.92 Michailidou, 2007, Omental 11beta-hydroxysteroid dehydrogenase 1 correlates with fat cell size independently of obesity, Obesity (Silver Spring), 15, 1155, 10.1038/oby.2007.618 Tomlinson, 2004, Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue, J Clin Endocrinol Metab, 89, 2711, 10.1210/jc.2003-031376 Divertie, 1991, Stimulation of lipolysis in humans by physiological hypercortisolemia, Diabetes, 40, 1228, 10.2337/diabetes.40.10.1228 Djurhuus, 2002, Effects of cortisol on lipolysis and regional interstitial glycerol levels in humans, Am J Physiol Endocrinol Metab, 283, E172, 10.1152/ajpendo.00544.2001 Slavin, 1994, Hormonal regulation of hormone-sensitive lipase activity and mRNA levels in isolated rat adipocytes, J Lipid Res, 35, 1535, 10.1016/S0022-2275(20)41151-4 Roberge, 2007, Adrenocortical dysregulation as a major player in insulin resistance and onset of obesity, Am J Physiol Endocrinol Metab, 293, E1465, 10.1152/ajpendo.00516.2007 Bjorntorp, 2000, Obesity and cortisol, Nutrition, 16, 924, 10.1016/S0899-9007(00)00422-6 Kershaw, 2005, Adipocyte-specific glucocorticoid inactivation protects against diet-induced obesity, Diabetes, 54, 1023, 10.2337/diabetes.54.4.1023 Morton, 2004, Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1–deficient mice, Diabetes, 53, 931, 10.2337/diabetes.53.4.931 Coutinho, 2006, Effect of voluntary exercise on peripheral tissue glucocorticoid receptor content and the expression and activity of 11beta-HSD1 in the Syrian hamster, J Appl Physiol, 100, 1483, 10.1152/japplphysiol.01236.2005 Taghibiglou, 2000, J Biol Chem, 275, 8416, 10.1074/jbc.275.12.8416 Taghibiglou, 2002, Hepatic very low density lipoprotein–ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance, J Biol Chem, 277, 793, 10.1074/jbc.M106737200 Coutinho, 2006, Metabolic effects of voluntary wheel running in young and old Syrian golden hamsters, Physiol.Behav., 87, 360, 10.1016/j.physbeh.2005.10.006 Hem, 1998, Saphenous vein puncture for blood sampling of the mouse, rat, hamster, gerbil, guinea pig, ferret and mink, Lab Anim, 32, 364, 10.1258/002367798780599866 Rao, 1992, Changes in insulin sensitivity from stress during repetitive sampling in anesthetized rats, Am J Physiol, 262, R1033 Gordon, 2001, Effects of contractile activity on mitochondrial transcription factor A expression in skeletal muscle, J Appl Physiol, 90, 389, 10.1152/jappl.2001.90.1.389 Riddell, 2003, The endocrine system: metabolic effects of the pancreatic, adrenal, thyroidal and growth hormones, 361 Enevoldsen, 2001, The effect of exercise training on hormone-sensitive lipase in rat intra-abdominal adipose tissue and muscle, J Physiol, 536, 871, 10.1111/j.1469-7793.2001.t01-1-00871.x Villena, 2004, Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis, J Biol Chem, 279, 47066, 10.1074/jbc.M403855200 Kershaw, 2004, Adipose tissue as an endocrine organ, J Clin Endocrinol Metab, 89, 2548, 10.1210/jc.2004-0395 Seckl, 2004, Glucocorticoids and 11beta-hydroxysteroid dehydrogenase in adipose tissue, Recent Prog Horm Res, 59, 359, 10.1210/rp.59.1.359 Fediuc, 2006, Effect of voluntary wheel running on circadian corticosterone release and on HPA axis responsiveness to restraint stress in Sprague-Dawley rats, J Appl Physiol, 100, 1867, 10.1152/japplphysiol.01416.2005 Kiraly, 2007, Attenuation of type 2 diabetes mellitus in the male Zucker diabetic fatty rat: the effects of stress and non-volitional exercise, Metabolism, 56, 732, 10.1016/j.metabol.2006.12.022 Park, 2005, Changes in basal hypothalamo-pituitary-adrenal activity during exercise training are centrally mediated, Am J Physiol Regul Integr Comp Physiol, 289, R1360, 10.1152/ajpregu.00103.2005