Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study

Siddiqi, 2020, COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal, J Heart Lung Transplant, 39, 405, 10.1016/j.healun.2020.03.012

Mehta, 2020, COVID-19: consider cytokine storm syndromes and immunosuppression, Lancet, 395, 1033, 10.1016/S0140-6736(20)30628-0

Tang, 2020, Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia, J Thromb Haemost, 18, 844, 10.1111/jth.14768

Panigada, 2020, Hypercoagulability of COVID-19 patients in intensive care unit. A report of thromboelastography findings and other parameters of hemostasis, J Thromb Haemost, 10.1111/jth.14850

Llitjos, 2020, High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients, J Thromb Haemost, 10.1111/jth.14869

Klok, 2020, Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: an updated analysis, Thromb Res, 191, 148, 10.1016/j.thromres.2020.04.041

Carsana, 2020, Pulmonary post-mortem findings in a large series of COVID-19 cases from Northern Italy, medRxiv

Ackermann, 2020, Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19, N Engl J Med, 10.1056/NEJMoa2015432

Varga, 2020, Endothelial cell infection and endotheliitis in COVID-19, Lancet, 395, 1417, 10.1016/S0140-6736(20)30937-5

Helms, 2020, High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study, Intensive Care Med, 46, 1089, 10.1007/s00134-020-06062-x

Escher, 2020, Severe COVID-19 infection associated with endothelial activation, Thromb Res, 190, 62, 10.1016/j.thromres.2020.04.014

López-Aguirre, 1999, Endothelial cell and hemostatic activation in relation to cytokines in patients with sepsis, Thromb Res, 94, 95, 10.1016/S0049-3848(98)00200-X

Nawroth, 1999, Thrombomodulin and coronary heart disease, Lancet, 353, 1722, 10.1016/S0140-6736(99)90039-9

Aso, 2000, Relationship between soluble thrombomodulin in plasma and coagulation or fibrinolysis in type 2 diabetes, Clin Chim Acta, 301, 135, 10.1016/S0009-8981(00)00335-1

Asakura, 2001, An enhanced fibrinolysis prevents the development of multiple organ failure in disseminated intravascular coagulation in spite of much activation of blood coagulation, Crit Care Med, 29, 1164, 10.1097/00003246-200106000-00015

Makrilakis, 2015, Interrelated reduction of chemerin and plasminogen activator inhibitor-1 serum levels in rheumatoid arthritis after interleukin-6 receptor blockade, Clin Rheumatol, 34, 419, 10.1007/s10067-014-2704-1

Gralinski, 2013, Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury, MBio, 4, 1, 10.1128/mBio.00271-13

Handt, 1996, Plasminogen activator inhibitor-1 secretion of endothelial cells increases fibrinolytic resistance of an in vitro fibrin clot: evidence for a key role of endothelial cells in thrombolytic resistance, Blood, 87, 4204, 10.1182/blood.V87.10.4204.bloodjournal87104204

Rubin, 1990, Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome, J Clin Invest, 86, 474, 10.1172/JCI114733

Kayal, 1998, Elevated circulating E-selectin, intercellular adhesion molecule 1, and von Willebrand factor in patients with severe infection, Am J Respir Crit Care Med, 157, 776, 10.1164/ajrccm.157.3.9705034

Yadav, 2015, Platelets in the pathogenesis of acute respiratory distress syndrome, Am J Physiol Lung Cell Mol Physiol, 309, L915, 10.1152/ajplung.00266.2015

Bunte, 2008, Pulmonary veno-occlusive disease following hematopoietic stem cell transplantation: a rare model of endothelial dysfunction, Bone Marrow Transplant, 41, 677, 10.1038/sj.bmt.1705990

Johansen, 2015, Profound endothelial damage predicts impending organ failure and death in sepsis, Semin Thromb Hemost, 41, 16, 10.1055/s-0034-1398377

Levi, 2018, How I treat disseminated intravascular coagulation, Blood, 131, 845, 10.1182/blood-2017-10-804096

Levi, 2018, The role of ADAMTS-13 in the coagulopathy of sepsis, J Thromb Haemost, 16, 646, 10.1111/jth.13953

Yasmeen, 2019, Cyclic nucleotide phosphodiesterases (PDEs) and endothelial function in ischaemic stroke. A review, Cell Signal, 61, 108, 10.1016/j.cellsig.2019.05.011

Liu, 2020, Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19, Acta Pharm Sin B

Diurno, 2020, Eculizumab treatment in patients with COVID-19: preliminary results from real life ASL Napoli 2 Nord experience, Eur Rev Med Pharmacol Sci, 24, 4040

Kerr, 2001, Interleukin 6 and haemostasis, Br J Haematol, 115, 3, 10.1046/j.1365-2141.2001.03061.x