Endoplasmic reticulum calcium storage and release in cells expressing misfolded growth hormone

Growth Hormone & IGF Research - Tập 13 - Trang 36-43 - 2003
Thomas K. Graves1, Patricia M. Hinkle1
1Department of Pharmacology and Physiology, University of Rochester Medical Center, Box 711, 601 Elmwood Avenue, Rochester, NY 14642, USA

Tài liệu tham khảo

Phillips, 1994, Genetic basis of endocrine disease. 6. Molecular basis of familial human growth hormone deficiency, J. Clin. Endocrinol. Metab., 78, 11, 10.1210/jc.78.1.11 Cogan, 1995, A recurring dominant negative mutation causes autosomal dominant growth hormone deficiency—a clinical research center study, J. Clin. Endocrinol. Metab., 80, 3591, 10.1210/jc.80.12.3591 Cogan, 1994, Familial growth hormone deficiency: a model of dominant and recessive mutations affecting a monomeric protein, J. Clin. Endocrinol. Metab., 79, 1261, 10.1210/jc.79.5.1261 de Vos, 1992, Human growth hormone and extracellular domain of its receptor: crystal structure of the complex, Science, 255, 306, 10.1126/science.1549776 Lee, 2000, Autosomal dominant growth hormone (GH) deficiency type II: the Δ32–71-GH deletion mutant suppresses secretion of wild-type GH, Endocrinology, 141, 883, 10.1210/en.141.3.883 Graves, 2001, Misfolded growth hormone causes fragmentation of the Golgi apparatus and disrupts endoplasmic reticulum-to-Golgi traffic, J. Cell Sci., 114, 3685, 10.1242/jcs.114.20.3685 L. McGuinness, C. Magoulas, K. Mathers, D. Carmignac, J.B. Manneville, H. Christian, J.A. Phillips III, I.C. Robinson, Autosomal dominant growth hormone deficiency disrupts secretory vesicles in vitro and in vivo in transgenic mice, Endocrinology (in press) Holl, 1988, Intracellular calcium concentration and growth hormone secretion in individual somatotropes: effects of growth hormone-releasing factor and somatostatin, Endocrinology, 122, 2927, 10.1210/endo-122-6-2927 Smith, 1997, Peptidomimetic regulation of growth hormone secretion, Endocr. Rev., 18, 621, 10.1210/er.18.5.621 Berridge, 1993, Inositol trisphosphate and calcium signalling, Nature, 361, 315, 10.1038/361315a0 Paschen, 2001, Dependence of vital cell function on endoplasmic reticulum calcium levels: implications for the mechanisms underlying neuronal cell injury in different pathological states, Cell Calcium, 29, 1, 10.1054/ceca.2000.0162 Lam, 1994, Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes, Proc. Natl. Acad. Sci. USA, 91, 6569, 10.1073/pnas.91.14.6569 He, 1997, Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl- 2, J. Cell Biol., 138, 1219, 10.1083/jcb.138.6.1219 Katayama, 1999, Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response, Nat. Cell Biol., 1, 479, 10.1038/70265 Kruman II, 1999, ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis, Exp. Neurol., 160, 28, 10.1006/exnr.1999.7190 Tsai, 1998, Adrenergic nerve smooth endoplasmic reticulum calcium buffering declines with age, Neurobiol. Aging, 19, 89, 10.1016/S0197-4580(98)00008-6 Kohno, 1997, Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil, Neurosci. Lett., 224, 17, 10.1016/S0304-3940(97)13459-0 Miyawaki, 1997, Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin [see comments], Nature, 388, 882, 10.1038/42264 Miyawaki, 1999, Dynamic and quantitative Ca2+ measurements using improved cameleons, Proc. Natl. Acad. Sci. USA, 96, 2135, 10.1073/pnas.96.5.2135 Bygrave, 1996, What is the concentration of calcium ions in the endoplasmic reticulum?, Cell Calcium, 19, 547, 10.1016/S0143-4160(96)90064-0 Hayashi, 1999, Inhibition of growth hormone (GH) secretion by a mutant GH-I gene product in neuroendocrine cells containing secretory granules: an implication for isolated GH deficiency inherited in an autosomal dominant manner, J. Clin. Endocrinol. Metab., 84, 2134, 10.1210/jc.84.6.2134 Kuznetsov, 1998, Folding of secretory and membrane proteins, N. Engl. J. Med., 339, 1688, 10.1056/NEJM199812033392307 Perlmutter, 1999, Misfolded proteins in the endoplasmic reticulum, Lab. Invest., 79, 623 Ellgaard, 1999, Setting the standards: quality control in the secretory pathway, Science, 286, 1882, 10.1126/science.286.5446.1882 Kaushal, 1994, Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa, Biochemistry, 33, 6121, 10.1021/bi00186a011 Sung, 1993, Rhodopsin mutations responsible for autosomal dominant retinitis pigmentosa. Clustering of functional classes along the polypeptide chain, J. Biol. Chem., 268, 26645, 10.1016/S0021-9258(19)74360-9 Ito, 1997, Molecular basis of autosomal dominant neurohypophyseal diabetes insipidus. Cellular toxicity caused by the accumulation of mutant vasopressin precursors within the endoplasmic reticulum, J. Clin. Invest., 99, 1897, 10.1172/JCI119357 Wu, 1994, A lag in intracellular degradation of mutant α1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ α1-antitrypsin deficiency, Proc. Natl. Acad. Sci. USA, 91, 9014, 10.1073/pnas.91.19.9014 Chapman, 1998, Intracellular signaling from the endoplasmic reticulum to the nucleus, Annu. Rev. Cell Dev. Biol., 14, 459, 10.1146/annurev.cellbio.14.1.459 Kaufman, 1999, Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls, Genes Dev., 13, 1211, 10.1101/gad.13.10.1211 Mori, 2000, Tripartite management of unfolded proteins in the endoplasmic reticulum, Cell, 101, 451, 10.1016/S0092-8674(00)80855-7 Sidrauski, 1998, The unfolded protein response: an intracellular signalling pathway with many surprising features, Trends Cell Biol., 8, 245, 10.1016/S0962-8924(98)01267-7 Lipton, 1999, Ischemic cell death in brain neurons, Physiol. Rev., 79, 1431, 10.1152/physrev.1999.79.4.1431 Preston, 1997, Effects of alterations in calcium homeostasis on apoptosis during neoplastic progression, Cancer Res., 57, 537 Bian, 1997, Poles of cytoplasmic Ca2+ and intracellular Ca2+ stores in induction and suppression of apoptosis in S49 cells, Am. J. Physiol., 272, C1241, 10.1152/ajpcell.1997.272.4.C1241 Berg, 1995, Kainic acid-induced seizures and brain damage in the rat: role of calcium homeostasis, J. Neurosci. Res., 40, 641, 10.1002/jnr.490400509 Yu, 1999, The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis, Exp. Neurol., 155, 302, 10.1006/exnr.1998.7002 Chiou, 1995, Prevention and reduction of neural damage in ischemic strokes by w-(N,N′-diethylamino)-n-alkyl-3,4,5-trimethoxybenzoate compounds, J. Pharmacol. Exp. Ther., 275, 474