Emx2 Promotes Symmetric Cell Divisions and a Multipotential Fate in Precursors from the Cerebral Cortex

Molecular and Cellular Neurosciences - Tập 18 - Trang 485-502 - 2001
Nico Heins1, Federico Cremisi2, Paolo Malatesta1, Rosaria M.R. Gangemi3, Giorgio Corte3, Jack Price4, Guy Goudreau5, Peter Gruss6, Magdalena Götz1
1Max-Planck Institute for Neurobiology, Munich, Germany
2Scuola Normale Superiore, Pisa, Italy
3Laboratory of Developmental Biology IST, Medical School, Genova, Italy
4Institute of Psychiatry, London, Great Britain
5Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany
6Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany

Tài liệu tham khảo

Anderson, 1989, The neural crest cell lineage problem: Neuropoiesis?, Neuron, 3, 1, 10.1016/0896-6273(89)90110-4 Bayer, 1991 Austin, 1995, Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch, Development, 121, 3637 Bansal, 1989, Multiple and novel specificities of monoclonal antibodies O1, O4 and R-mAb used in the analysis of oligodendrocyte development, J. Neurosci. Res., 24, 548, 10.1002/jnr.490240413 Bignami, 1972, Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence, Brain Res., 43, 429, 10.1016/0006-8993(72)90398-8 Bishop, 2000, Regulation of area identity in the mammalian neocortex by Emx2 and Pax6, Science, 288, 344, 10.1126/science.288.5464.344 Cai, 1997, Local homogeneity of cell cycle length in developing mouse cortex, J. Neurosci., 17, 2079, 10.1523/JNEUROSCI.17-06-02079.1997 Chenn, 1995, Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis, Cell, 82, 631, 10.1016/0092-8674(95)90035-7 Dalton, 1989, Expression and embryonic function of empty spiracles, a Drosophila homeobox gene with two patterning functions in the anterior–posterior axis of the embryo, Genes Dev., 3, 1940, 10.1101/gad.3.12a.1940 Dorsky, 1995, Xotch inhibits cell differentiation in the Xenopus retina, Neuron, 14, 487, 10.1016/0896-6273(95)90305-4 Durand, 2000, A cell-intrinsic timer that operates during oligodendrocyte development, BioEssays, 22, 64, 10.1002/(SICI)1521-1878(200001)22:1<64::AID-BIES11>3.0.CO;2-Q Enver, 1999, B-cell commitment: Pax5 is the deciding factor, Curr. Biol., 9, R933, 10.1016/S0960-9822(00)80108-6 Frederiksen, 1988, Proliferation and differentiation of rat neuroepithelial precursor cells in vivo, J. Neurosci., 8, 1144, 10.1523/JNEUROSCI.08-04-01144.1988 Furukawa, 2000, Rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells, Neuron, 26, 383, 10.1016/S0896-6273(00)81171-X Gaiano, 2000, Radial glial identity is promoted by Notch1 signaling in the murine forebrain, Neuron, 26, 395, 10.1016/S0896-6273(00)81172-1 Ghattas, 1991, The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos, Mol. Cell. Biol., 11, 5848, 10.1128/MCB.11.12.5848 Götz, 1995, The specification of neuronal fate: A common precursor for neurotransmitter subtypes in the rat cerebral cortex in vitro, Eur. J. Neurosci., 7, 889, 10.1111/j.1460-9568.1995.tb01076.x Götz, 1998, Pax6 controls radial glia differentiation in the cerebral cortex, Neuron, 21, 1031, 10.1016/S0896-6273(00)80621-2 Grove, 1993, Multiple restricted lineages in the embryonic rat cerebral cortex, Development, 117, 553 Gulisano, 1996, Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex in the mouse, Eur. J. Neurosci., 8, 1037, 10.1111/j.1460-9568.1996.tb01590.x Hartfuss, 2001, Characterization of CNS precursor subtypes and radial glia, Dev. Biol., 229, 15, 10.1006/dbio.2000.9962 Hajihosseini, 1993, Evidence that retroviruses integrate into post-replicational host DNA, EMBO J., 12, 4969, 10.1002/j.1460-2075.1993.tb06190.x Hajihosseini, 1999, A subset of fibroblast growth factors (Fgfs) promote survival, but Fgf-8b specifically promotes astroglial differentiation of rat cortical precursor cells, Mol. Cell. Neurosci., 14, 468, 10.1006/mcne.1999.0800 Haydar, 1999, Organotypic slice cultures for analysis of proliferation, cell death, and migration in the embryonic neocortex, Brain Res. Protocols, 4, 425, 10.1016/S1385-299X(99)00033-1 Hojo, 2000, Glial cell fate specification modulated by the bHLH gene Hes5 in mouse retina, Development, 127, 2515 Huttner, 1997, Asymmetric division and polarity of neuroepithelial cells, Curr. Opin. Neurobiol., 7, 29, 10.1016/S0959-4388(97)80117-1 Ishibashi, 1994, Persistent expression of helix–loop–helix-factor HES-1 prevents mammalian neural differentiation in the central nervous system, EMBO J., 13, 1799, 10.1002/j.1460-2075.1994.tb06448.x Johe, 1996, Single factors direct the differentiation of stem cells from the fetal and adult central nervous system, Genes Dev., 10, 3129, 10.1101/gad.10.24.3129 Lardelli, 1996, Expression of the Notch3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development, Mech. Dev., 59, 177, 10.1016/0925-4773(96)00589-8 Lavdas, 1996, Neuronal clones in the cerebral cortex show morphological and neurotransmitter heterogeneity during development, Cerebral Cortex, 6, 490, 10.1093/cercor/6.3.490 Lee, 1990, The expression and posttranslational modification of a neuron-specific b-tubulin isotype during chick embryogenesis, Cell Mot. Cyt., 17, 118, 10.1002/cm.970170207 Lillien, 1997, Neural development: Instructions for neural diversity, Curr. Biol., 7, R168, 10.1016/S0960-9822(97)70080-0 Luskin, 1988, Cell lineage in mouse cerebral cortex studied in vivo and in vitro with a retroviral vector, Neuron, 1, 635, 10.1016/0896-6273(88)90163-8 Malatesta, 2000, Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage, Development, 127, 5253 Malatesta, 2000, PC3 overexpression affects the pattern of cell division of rat cortical precursors, Mech. Dev., 90, 17, 10.1016/S0925-4773(99)00224-5 Mallamaci, 1998, EMX2 protein in the developing mouse brain and olfactory area, Mech. Dev., 77, 165, 10.1016/S0925-4773(98)00141-5 Mallamaci, 2000, The lack of Emx2 causes impairment of Reelin signaling and defects of neuronal migration in the developing cerebral cortex, J. Neurosci., 20, 1109, 10.1523/JNEUROSCI.20-03-01109.2000 Mallamaci, 2000, Area identity shifts in the early cerebral cortex of Emx2−/− mutant mice, Nat. Neurosci., 3, 679, 10.1038/76630 Morrison, 2000, Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells, Cell, 101, 499, 10.1016/S0092-8674(00)80860-0 Nakamura, 2000, The bHLH gene Hes1 as a repressor of the neuronal commitment of CNS stem cells, J. Neurosci., 20, 283, 10.1523/JNEUROSCI.20-01-00283.2000 Noctor, 2001, Neurons derived from radial glial cells establish radial units in neocortex, Nature, 409, 714, 10.1038/35055553 Nowakowski, 1989, Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population, J. Neurocytol., 18, 311, 10.1007/BF01190834 Pear, 1993, Production of high-titer helper-free retroviruses by transient transfection, Proc. Natl. Acad. Sci. USA, 90, 8392, 10.1073/pnas.90.18.8392 Pellegrini, 1996, Dentate gyrus formation requires Emx2, Development, 122, 3893 Price, 1987, Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer, Proc. Natl. Acad. Sci. USA, 84, 156, 10.1073/pnas.84.1.156 Price, 1988, Cell lineage in the rat cerebral cortex: A study using retroviral-mediated gene transfer, Development, 104, 473 Qian, 1998, Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cells, Development, 125, 3143 Qian, 2000, Timing of CNS cell generation: A programmed sequence of neuron and glial cell production from isolated murine cortical stem cells, Neuron, 28, 69, 10.1016/S0896-6273(00)00086-6 Rakic, 1995, A small step for the cell, a giant leap for mankind: A hypothesis of neocortical expansion during evolution, Trends Neurochem. Sci., 18, 383, 10.1016/0166-2236(95)93934-P Reid, 1995, Systematic widespread clonal organization in cerebral cortex, Neuron, 15, 299, 10.1016/0896-6273(95)90035-7 Reynolds, 1992, Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system, Science, 255, 1707, 10.1126/science.1553558 Roe, 1993, Integration of murine leukemia virus DNA depends on mitosis, EMBO J., 12, 2099, 10.1002/j.1460-2075.1993.tb05858.x Shen, 1998, Stem cells in the embryonic cerebral cortex: Their role in histogenesis and patterning, J. Neurobiol., 36, 162, 10.1002/(SICI)1097-4695(199808)36:2<162::AID-NEU5>3.0.CO;2-# Simeone, 1992, Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex, EMBO J., 11, 2541, 10.1002/j.1460-2075.1992.tb05319.x Takahashi, 1993, Cell cycle parameters and patterns of nuclear movements in the neocortical proliferative zone of the fetal mouse, J. Neurosci., 13, 820, 10.1523/JNEUROSCI.13-02-00820.1993 Takahashi, 1999, Sequence of neuron origin and neocortical laminar fate: Relation to cell cycle of origin in the developing murine cerebral wall, J. Neurosci., 19, 10357, 10.1523/JNEUROSCI.19-23-10357.1999 Tole, 2000, Emx2 is required for growth of the hippocampus but not for hippocampal field specification, J. Neurosci., 20, 2618, 10.1523/JNEUROSCI.20-07-02618.2000 Vaccarino, 1999, Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis, Nature, 2, 246 Walsh, 1992, Widespread dispersion of neuronal clones across functional regions of the cerebral cortex, Science, 255, 434, 10.1126/science.1734520 Walsh, 1993, Clonal dispersion in proliferative layers of developing cerebral cortex, Nature, 362, 632, 10.1038/362632a0 Walther, 1991, Pax6, a murine paired box gene is expressed in the developing CNS, Development, 113, 1435 Watt, 2000, Out of Eden: Stem cells and their niches, Science, 287, 1427, 10.1126/science.287.5457.1427 Williams, 1991, The generation of neurons and oligodendrocytes from a common precursor cell, Neuron, 7, 685, 10.1016/0896-6273(91)90381-9 Williams, 1995, Evidence for multiple precursor cell types in the embryonic rat cerebral cortex, Neuron, 14, 1181, 10.1016/0896-6273(95)90265-1 Yoshida, 1997, Emx1 and Emx2 functions in development of dorsal telencephalon, Development, 124, 101