Emulsion template fabricated gelatin-based scaffold functionalized by dialdehyde starch complex with antibacterial antioxidant properties for accelerated wound healing

Arwert, 2012, Epithelial stem cells, wound healing and cancer, Nat. Rev. Cancer, 12, 170, 10.1038/nrc3217 Yu, 2016, An elastic second skin, Nat. Mater., 15, 911, 10.1038/nmat4635 Liang, 2021, Functional hydrogels as wound dressing to enhance wound healing, ACS Nano, 10.1021/acsnano.1c04206 Cheng, 2022, Dendritic hydrogels with robust inherent antibacterial properties for promoting bacteria-infected wound healing, ACS Appl. Mater. Interfaces, 14, 11144, 10.1021/acsami.1c25014 Zhao, 2017, Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing, Biomaterials, 122, 34, 10.1016/j.biomaterials.2017.01.011 Xu, 2022, Novel glucose-responsive antioxidant hybrid hydrogel for enhanced diabetic wound repair, ACS Appl. Mater. Interfaces, 14, 7680, 10.1021/acsami.1c23461 Safari, 2022, A bioactive porous scaffold containing collagen/phosphorous-modified polycaprolactone for osteogenesis of adipose-derived mesenchymal stem cells, Eur. Polym. J., 171, 10.1016/j.eurpolymj.2022.111220 Hu, 2020, Thermal-disrupting interface mitigates intercellular cohesion loss for accurate topical antibacterial therapy, Adv. Mater., 32, 1907030, 10.1002/adma.201907030 Wang, 2021, Functionalization of an electroactive self-healing polypyrrole-grafted gelatin-based hydrogel by incorporating a polydopamine@AgNP nanocomposite, ACS Appl. Bio Mater., 4, 5797, 10.1021/acsabm.1c00548 Wang, 2022, Endogenous electric-field-coupled electrospun short fiber via collecting wound exudation, Adv. Mater., 34, 2108325, 10.1002/adma.202108325 Lyu, 2017, Using oxidized amylose as carrier of linalool for the development of antibacterial wound dressing, Carbohydr. Polym., 174, 1095, 10.1016/j.carbpol.2017.07.033 Ge, 2018, Fabrication of antibacterial collagen-based composite wound dressing, ACS Sustain. Chem. Eng., 6, 9153, 10.1021/acssuschemeng.8b01482 Huang, 2017, Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment, Chem. Rev., 117, 12764, 10.1021/acs.chemrev.7b00094 Oh, 2007, In vitro and in vivo characteristics of PCL scaffolds with pore size gradient fabricated by a centrifugation method, Biomaterials, 28, 1664, 10.1016/j.biomaterials.2006.11.024 Costantini, 2018, Electric field assisted microfluidic platform for generation of tailorable porous microbeads as cell carriers for tissue engineering, Adv. Funct. Mater., 28, 1800874, 10.1002/adfm.201800874 Yuan, 2019, Emulsion template method for the fabrication of gelatin-based scaffold with a controllable pore structure, ACS Appl. Mater. Interfaces, 11, 269, 10.1021/acsami.8b17555 Hosseini, 2021, Engineering bioactive scaffolds for skin regeneration, Small, 17, 2101384, 10.1002/smll.202101384 Huang, 2022, Biodegradable gelatin/silver nanoparticle composite cryogel with excellent antibacterial and antibiofilm activity and hemostasis for Pseudomonas aeruginosa-infected burn wound healing, J. Colloid Interface Sci., 608, 2278, 10.1016/j.jcis.2021.10.131 Ding, 2017, Spongy bilayer dressing composed of chitosan-ag nanoparticles and chitosan-Bletilla striata polysaccharide for wound healing applications, Carbohydr. Polym., 157, 1538, 10.1016/j.carbpol.2016.11.040 Yuan, 2021, Nano-silver functionalized polysaccharides as a platform for wound dressings: a review, Int. J. Biol. Macromol., 194 Lyu, 2019, Synthesis of silver nanoparticles using oxidized amylose and combination with curcumin for enhanced antibacterial activity, Carbohydr. Polym., 230 Zhu, 2019, Green synthesis of κ-carrageenan@ag submicron-particles with high aqueous stability, robust antibacterial activity and low cytotoxicity, Mater. Sci. Eng., C 106 Xu, 2014, Green synthesis of xanthan conformation-based silver nanoparticles: antibacterial and catalytic application, Carbohydr. Polym., 101, 961, 10.1016/j.carbpol.2013.10.032 Zou, 2022, Covalent organic framework-incorporated nanofibrous membrane as an intelligent platform for wound dressing, ACS Appl. Mater. Interfaces, 14, 10.1021/acsami.1c19754 Hofreiter, 1955, Rapid estimation of dialdehyde content of periodate oxystarch through quantitative alkali consumption, Anal. Chem., 27, 1930, 10.1021/ac60108a023 Lei, 2019, Facile fabrication of biocompatible gelatin-based self-healing hydrogels, ACS Appl. Polym. Mater., 1, 1350, 10.1021/acsapm.9b00143 Yuan, 2022, Functionalization of an injectable self-healing ph-responsive hydrogel by incorporating a curcumin/polymerized β-cyclodextrin inclusion complex for selective toxicity to osteosarcoma, ACS Appl. Polym. Mater., 4, 10.1021/acsapm.1c01637 Ye, 2017, Synthesis of oxidized β-cyclodextrin with high aqueous solubility and broad-spectrum antimicrobial activity, Carbohydr. Polym., 177, 97, 10.1016/j.carbpol.2017.08.123 Li, 2015, Gelatin effects on the physicochemical and hemocompatible properties of gelatin/PAAm/laponite nanocomposite hydrogels, ACS Appl. Mater. Interfaces, 7, 18732, 10.1021/acsami.5b05287 Zhao, 2020, Controlling the pore structure of collagen sponge by adjusting the cross-linking degree for construction of heterogeneous double-layer bone barrier membranes, ACS Appl. Bio Mater., 3, 2058, 10.1021/acsabm.9b01175 Zi, 2018, Effects of carboxyl and aldehyde groups on the antibacterial activity of oxidized amylose, Carbohydr. Polym., 192, 118, 10.1016/j.carbpol.2018.03.060 Zhou, 2016, Oxidized amylose with high carboxyl content: a promising solubilizer and carrier of linalool for antimicrobial activity, Carbohydr. Polym., 154, 13, 10.1016/j.carbpol.2016.08.030 Travan, 2009, Non-cytotoxic silver nanoparticle-polysaccharide nanocomposites with antimicrobial activity, Biomacromolecules, 10, 1429, 10.1021/bm900039x Zhang, 2012, Preparation and properties of oxidized starch with high degree of oxidation, Carbohydr. Polym., 87, 2554, 10.1016/j.carbpol.2011.11.036 Zhou, 2016, Effect of oxidation level on the inclusion capacity and solution stability of oxidized amylose in aqueous solution, Carbohydr. Polym., 138, 41, 10.1016/j.carbpol.2015.11.040 Luo, 2014, Green synthesis of silver nanoparticle in xylan solution via Tollens reaction and its detection for Hg2+, Nanoscale, 7 GhavamiNejad, 2016, In situ synthesis of antimicrobial silver nanoparticles within antifouling zwitterionic hydrogels by catecholic redox chemistry for wound healing application, Biomacromolecules, 17, 1213, 10.1021/acs.biomac.6b00039 Pietrzyk, 2012, The influence of cu(II) ions on physicochemical properties of potato starch oxidised by hydrogen peroxide, Starch-Starke, 64, 10.1002/star.201100090 Fan, 2014, A novel wound dressing based on ag/graphene polymer hydrogel: effectively kill Bacteria and accelerate wound healing, Adv. Funct. Mater., 24, 3933, 10.1002/adfm.201304202 Morry, 2017, Oxidative stress in cancer and fibrosis: opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles, Redox Biol., 11, 240, 10.1016/j.redox.2016.12.011 Schieber, 2014, ROS function in redox signaling and oxidative stress, Curr. Biol., 24, R453, 10.1016/j.cub.2014.03.034 Kant, 2014, Antioxidant and anti-inflammatory potential of curcumin accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats, Int. Immunopharmacol., 20, 322, 10.1016/j.intimp.2014.03.009 Roy, 2020, Carboxymethyl cellulose-based antioxidant and antimicrobial active packaging film incorporated with curcumin and zinc oxide, Int. J. Biol. Macromol., 148, 666, 10.1016/j.ijbiomac.2020.01.204 Ak, 2008, Antioxidant and radical scavenging properties of curcumin, Chem. Biol. Interact., 174, 27, 10.1016/j.cbi.2008.05.003 Zheng, 2020, Antibacterial mechanism of curcumin: a review, Chem. Biodivers., 17, 10.1002/cbdv.202000171 Shi, 2015, Enhanced colloidal stability and antibacterial performance of silver nanoparticles/cellulose nanocrystal hybrids, J. Mater. Chem. B, 3, 603, 10.1039/C4TB01647E Ramasamy, 2021, Antibacterial activity of silver nanoparticles (AgNps) synthesized by tea leaf extracts against pathogenic Vibrio harveyi and its protective efficacy on juvenile Feneropenaeus indicus, Lett. Appl. Microbiol., 50, 356 Panáček, 2006, Silver colloid nanoparticles: synthesis, characterization, and their antibacterial activity, J. Phys. Chem. B, 110, 16248, 10.1021/jp063826h De Clercq, 2016, Genipin-crosslinked gelatin microspheres as a strategy to prevent postsurgical peritoneal adhesions: in vitro and in vivo characterization, Biomaterials, 96, 33, 10.1016/j.biomaterials.2016.04.012 Wei, 2008, Monodisperse chitosan microspheres with interesting structures for protein drug delivery, Adv. Mater., 20, 2292, 10.1002/adma.200702663 Safari, 2023, Osteogenic differentiation of human adipose-derived mesenchymal stem cells in a bisphosphonate-functionalized polycaprolactone/gelatin scaffold, Int. J. Biol. Macromol., 241, 10.1016/j.ijbiomac.2023.124573 Safari, 2022, Biofunctional phosphorylated magnetic scaffold for bone tissue engineering, Colloids Surf. B: Biointerfaces, 211, 112284, 10.1016/j.colsurfb.2021.112284 Moglia, 2011, Injectable PolyHIPEs as high-porosity bone grafts, Biomacromolecules, 12, 3621, 10.1021/bm2008839 Jaiswal, 2015, Mechanically stiff nanocomposite hydrogels at ultralow nanoparticle content, ACS Nano, 10 Ge, 2015, Development and characterization of dialdehyde xanthan gum crosslinked gelatin based edible films incorporated with amino-functionalized montmorillonite, Food Hydrocoll., 51, 129, 10.1016/j.foodhyd.2015.04.029 Liu, 2019, Controlled-release neurotensin-loaded silk fibroin dressings improve wound healing in diabetic rat model, Bioact. Mater., 4, 151 Priya, 2016, Bilayer cryogel wound dressing and skin regeneration grafts for the treatment of acute skin wounds, ACS Appl. Mater. Interfaces, 8, 15145, 10.1021/acsami.6b04711 Liang, 2021, Dual-dynamic-bond cross-linked antibacterial adhesive hydrogel sealants with on-demand removability for post-wound-closure and infected wound healing, ACS Nano, 15, 7078, 10.1021/acsnano.1c00204 Wang, 2020, Fabrication of polypyrrole-grafted gelatin-based hydrogel with conductive, self-healing, and injectable properties, ACS Appl. Polym. Mater., 2, 3016, 10.1021/acsapm.0c00468 Menner, 2007, Particle-stabilized surfactant-free medium internal phase emulsions as templates for porous nanocomposite materials: poly-Pickering-foams, Langmuir, 23, 2398, 10.1021/la062712u Tan, 2017, Interconnected macroporous 3D scaffolds templated from gelatin nanoparticle-stabilized high internal phase emulsions for biomedical applications, Soft Matter, 13, 3871, 10.1039/C7SM00706J Gorbet, 2004, Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes, Biomaterials, 25, 5681, 10.1016/j.biomaterials.2004.01.023 O’Brien, 2005, The effect of pore size on cell adhesion in collagen-GAG scaffold, Biomaterials, 26, 433, 10.1016/j.biomaterials.2004.02.052