Emerging roles of the neurotrophin receptor TrkC in synapse organization

Neuroscience Research - Tập 116 - Trang 10-17 - 2017
Yusuke Naito1,2, Alfred Kihoon Lee1,2, Hideto Takahashi1,2,3,4
1Synapse Development and Plasticity, Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Quebec H2W 1R7, Canada
2Integrated Program in Neuroscience, McGill University, Montreal, Quebec H3A 2B4, Canada
3Department of Medicine, Université de Montréal, Montreal, Quebec H3T 1J4, Canada
4Division of Experimental Medicine, McGill University, Montreal, Quebec H3A 1A3, Canada

Tài liệu tham khảo

Alonso, 2008, Genetic susceptibility to obsessive–compulsive hoarding: the contribution of neurotrophic tyrosine kinase receptor type 3 gene, Genes Brain Behav., 7, 778, 10.1111/j.1601-183X.2008.00418.x Ammendrup-Johnsen, 2015, Neurotrophin-3 enhances the synaptic organizing function of TrkC-protein tyrosine phosphatase sigma in rat hippocampal neurons, J. Neurosci., 35, 12425, 10.1523/JNEUROSCI.1330-15.2015 Armengol, 2002, 5′ UTR-region SNP in the NTRK3 gene is associated with panic disorder, Mol. Psychiatry, 7, 928, 10.1038/sj.mp.4001134 Barbacid, 1994, The Trk family of neurotrophin receptors, J. Neurobiol., 25, 1386, 10.1002/neu.480251107 Barbacid, 1991, The trk family of tyrosine protein kinase receptors, Biochim. Biophys. Acta, 1072, 115 Bashaw, 2010, Signaling from axon guidance receptors, Cold Spring Harb. Perspect. Biol., 2, a001941, 10.1101/cshperspect.a001941 Betancur, 2009, The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders, Trends Neurosci., 32, 402, 10.1016/j.tins.2009.04.003 Chalazonitis, 1996, Neurotrophin-3 as an essential signal for the developing nervous system, Mol. Neurobiol., 12, 39, 10.1007/BF02740746 Chao, 2003, Neurotrophins and their receptors: a convergence point for many signalling pathways, Nat. Rev. Neurosci., 4, 299, 10.1038/nrn1078 Coles, 2014, Structural basis for extracellular cis and trans RPTPsigma signal competition in synaptogenesis, Nat. Commun., 5, 5209, 10.1038/ncomms6209 Craig, 2007, Neurexin–neuroligin signaling in synapse development, Curr. Opin. Neurobiol., 17, 43, 10.1016/j.conb.2007.01.011 Dalva, 2007, Cell adhesion molecules: signalling functions at the synapse, Nat. Rev. Neurosci., 8, 206, 10.1038/nrn2075 de Wit, 2016, Specification of synaptic connectivity by cell surface interactions, Nat. Rev. Neurosci., 17, 22, 10.1038/nrn.2015.3 de Wit, 2009, LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation, Neuron, 64, 799, 10.1016/j.neuron.2009.12.019 Dean, 2003, Neurexin mediates the assembly of presynaptic terminals, Nat. Neurosci., 6, 708, 10.1038/nn1074 Desbois, 2015, Directional trans-synaptic labeling of specific neuronal connections in live animals, Genetics, 200, 697, 10.1534/genetics.115.177006 Dierssen, 2006, Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction, Neurobiol. Dis., 24, 403, 10.1016/j.nbd.2006.07.015 Donovan, 1996, Identification of an essential nonneuronal function of neurotrophin 3 in mammalian cardiac development, Nat. Genet., 14, 210, 10.1038/ng1096-210 Elchebly, 1999, Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma, Nat. Genet., 21, 330, 10.1038/6859 Esteban, 2006, A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin, J. Cell Biol., 173, 291, 10.1083/jcb.200512013 Fallin, 2005, Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios, Am. J. Hum. Genet., 77, 918, 10.1086/497703 Graf, 2004, Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins, Cell, 119, 1013, 10.1016/j.cell.2004.11.035 Gratacos, 2001, A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders, Cell, 106, 367, 10.1016/S0092-8674(01)00447-0 Han, 2016, Neurotrophin-3 regulates synapse development by modulating TrkC-PTPsigma synaptic adhesion and intracellular signaling pathways, J. Neurosci., 36, 4816, 10.1523/JNEUROSCI.4024-15.2016 Hapner, 1998, Neural differentiation promoted by truncated trkC receptors in collaboration with p75NTR, Dev. Biol., 201, 90, 10.1006/dbio.1998.8970 Henion, 1995, trkC-mediated NT-3 signaling is required for the early development of a subpopulation of neurogenic neural crest cells, Dev. Biol., 172, 602, 10.1006/dbio.1995.8054 Horn, 2012, Receptor protein tyrosine phosphatase sigma regulates synapse structure, function and plasticity, J. Neurochem., 122, 147, 10.1111/j.1471-4159.2012.07762.x Huang, 2003, Trk receptors: roles in neuronal signal transduction, Annu. Rev. Biochem., 72, 609, 10.1146/annurev.biochem.72.121801.161629 Iijima, 2011, SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1, Cell, 147, 1601, 10.1016/j.cell.2011.11.028 Jamain, 2003, Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism, Nat. Genet., 34, 27, 10.1038/ng1136 Johnson, 2003, Receptor protein tyrosine phosphatases in nervous system development, Physiol. Rev., 83, 1, 10.1152/physrev.00016.2002 Joo, 2014, Neurodevelopment. Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling, Science, 346, 626, 10.1126/science.1258996 Kang, 1995, Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus, Science, 267, 1658, 10.1126/science.7886457 Kang, 2008, Induction of GABAergic postsynaptic differentiation by alpha-neurexins, J. Biol. Chem., 283, 2323, 10.1074/jbc.M703957200 Kim, 2004, PDZ domain proteins of synapses, Nat. Rev. Neurosci., 5, 771, 10.1038/nrn1517 Klein, 1994, Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements, Nature, 368, 249, 10.1038/368249a0 Ko, 2009, LRRTM2 functions as a neurexin ligand in promoting excitatory synapse formation, Neuron, 64, 791, 10.1016/j.neuron.2009.12.012 Kolodkin, 2011, Mechanisms and molecules of neuronal wiring: a primer, Cold Spring Harb. Perspect. Biol., 3, 10.1101/cshperspect.a001727 Kwon, 2010, Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation, J. Biol. Chem., 285, 13966, 10.1074/jbc.M109.061127 Kwon, 2012, Neuroligin-1-dependent competition regulates cortical synaptogenesis and synapse number, Nat. Neurosci., 15, 1667, 10.1038/nn.3256 Linhoff, 2009, An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers, Neuron, 61, 734, 10.1016/j.neuron.2009.01.017 Ludwig, 2009, Supporting evidence for LRRTM1 imprinting effects in schizophrenia, Mol. Psychiatry, 14, 743, 10.1038/mp.2009.28 Maisonpierre, 1990, NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression, Neuron, 5, 501, 10.1016/0896-6273(90)90089-X Martell, 2016, A split horseradish peroxidase for the detection of intercellular protein–protein interactions and sensitive visualization of synapses, Nat. Biotechnol., 34, 774, 10.1038/nbt.3563 Meathrel, 2002, Protein tyrosine phosphatase sigma-deficient mice show aberrant cytoarchitecture and structural abnormalities in the central nervous system, J. Neurosci. Res., 70, 24, 10.1002/jnr.10382 Muinos-Gimeno, 2009, Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders, Hum. Mutat., 30, 1062, 10.1002/humu.21005 Nakazawa, 2006, NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity, EMBO J., 25, 2867, 10.1038/sj.emboj.7601156 Otnaess, 2009, Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia, Neurobiol. Dis., 34, 518, 10.1016/j.nbd.2009.03.011 Park, 2013, Neurotrophin regulation of neural circuit development and function, Nat. Rev. Neurosci., 14, 7, 10.1038/nrn3379 Pettem, 2013, The specific alpha-neurexin interactor calsyntenin-3 promotes excitatory and inhibitory synapse development, Neuron, 80, 113, 10.1016/j.neuron.2013.07.016 Pinto, 2010, Functional impact of global rare copy number variation in autism spectrum disorders, Nature, 466, 368, 10.1038/nature09146 Poo, 2001, Neurotrophins as synaptic modulators, Nat. Rev. Neurosci., 2, 24, 10.1038/35049004 Pulido, 1995, The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1, Proc. Natl. Acad. Sci. U. S. A., 92, 11686, 10.1073/pnas.92.25.11686 Ramos-Languren, 2013, Plasticity and metaplasticity of adult rat hippocampal mossy fibers induced by neurotrophin-3, Eur. J. Neurosci., 37, 1248, 10.1111/ejn.12141 Sahin, 1993, Protein tyrosine phosphatases expressed in the developing rat brain, J. Neurosci., 13, 4968, 10.1523/JNEUROSCI.13-11-04968.1993 Scheiffele, 2000, Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons, Cell, 101, 657, 10.1016/S0092-8674(00)80877-6 Schinder, 2000, Postsynaptic target specificity of neurotrophin-induced presynaptic potentiation, Neuron, 25, 151, 10.1016/S0896-6273(00)80879-X Shen, 2010, Genetics and cell biology of building specific synaptic connectivity, Annu. Rev. Neurosci., 33, 473, 10.1146/annurev.neuro.051508.135302 Siddiqui, 2011, Synaptic organizing complexes, Curr. Opin. Neurobiol., 21, 132, 10.1016/j.conb.2010.08.016 Siddiqui, 2010, LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development, J. Neurosci., 30, 7495, 10.1523/JNEUROSCI.0470-10.2010 Siu, 2007, N-Cadherin is an in vivo substrate for protein tyrosine phosphatase sigma (PTPsigma) and participates in PTPsigma-mediated inhibition of axon growth, Mol. Cell. Biol., 27, 208, 10.1128/MCB.00707-06 Stryker, 2007, LAR, liprin alpha and the regulation of active zone morphogenesis, J. Cell Sci., 120, 3723, 10.1242/jcs.03491 Sudhof, 2008, Neuroligins and neurexins link synaptic function to cognitive disease, Nature, 455, 903, 10.1038/nature07456 Tabuchi, 2007, A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice, Science, 318, 71, 10.1126/science.1146221 Takahashi, 2013, Protein tyrosine phosphatases PTPdelta, PTPsigma, and LAR: presynaptic hubs for synapse organization, Trends Neurosci., 36, 522, 10.1016/j.tins.2013.06.002 Takahashi, 2011, Postsynaptic TrkC and presynaptic PTPsigma function as a bidirectional excitatory synaptic organizing complex, Neuron, 69, 287, 10.1016/j.neuron.2010.12.024 Takahashi, 2012, Selective control of inhibitory synapse development by Slitrk3-PTPdelta trans-synaptic interaction, Nat. Neurosci., 15, 389, 10.1038/nn.3040 Tessarollo, 1997, Targeted deletion of all isoforms of the trkC gene suggests the use of alternate receptors by its ligand neurotrophin-3 in neuronal development and implicates trkC in normal cardiogenesis, Proc. Natl. Acad. Sci. U. S. A., 94, 14776, 10.1073/pnas.94.26.14776 Tessier-Lavigne, 1996, The molecular biology of axon guidance, Science, 274, 1123, 10.1126/science.274.5290.1123 Treutlein, 2009, Dissection of phenotype reveals possible association between schizophrenia and Glutamate Receptor Delta 1 (GRID1) gene promoter, Schizophr. Res., 111, 123, 10.1016/j.schres.2009.03.011 Tsetsenis, 2014, Direct visualization of trans-synaptic neurexin–neuroligin interactions during synapse formation, J. Neurosci., 34, 15083, 10.1523/JNEUROSCI.0348-14.2014 Urfer, 1995, An immunoglobulin-like domain determines the specificity of neurotrophin receptors, EMBO J., 14, 2795, 10.1002/j.1460-2075.1995.tb07279.x Urfer, 1998, High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptors, J. Biol. Chem., 273, 5829, 10.1074/jbc.273.10.5829 Valenzuela, 1993, Alternative forms of rat TrkC with different functional capabilities, Neuron, 10, 963, 10.1016/0896-6273(93)90211-9 Valnegri, 2011, The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPdelta and RhoGAP2, Hum. Mol. Genet., 20, 4797, 10.1093/hmg/ddr418 Verma, 2008, Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3, Biol. Psychiatry, 63, 1185, 10.1016/j.biopsych.2008.02.005 Vicario-Abejon, 1998, Neurotrophins induce formation of functional excitatory and inhibitory synapses between cultured hippocampal neurons, J. Neurosci., 18, 7256, 10.1523/JNEUROSCI.18-18-07256.1998 Vicario-Abejon, 2002, Role of neurotrophins in central synapse formation and stabilization, Nat. Rev. Neurosci., 3, 965, 10.1038/nrn988 Wallace, 1999, Neuronal defects and posterior pituitary hypoplasia in mice lacking the receptor tyrosine phosphatase PTPsigma, Nat. Genet., 21, 334, 10.1038/6866 Wang, 1994, Regulation of NMDA receptors by tyrosine kinases and phosphatases, Nature, 369, 233, 10.1038/369233a0 Woo, 2009, Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses, Nat. Neurosci., 12, 428, 10.1038/nn.2279 Yim, 2013, Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases, Proc. Natl. Acad. Sci. U. S. A., 110, 4057, 10.1073/pnas.1209881110 Yoshida, 2011, IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase delta, J. Neurosci., 31, 13485, 10.1523/JNEUROSCI.2136-11.2011 Yoshida, 2012, Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule, J. Neurosci., 32, 2588, 10.1523/JNEUROSCI.4637-11.2012