Emerging roles for chromatin remodeling in cancer biology

Workman, 1998, Alteration of nucleosome structure as a mechanism of transcriptional regulation, Annu. Rev. Biochem., 67, 545, 10.1146/annurev.biochem.67.1.545 Strahl, 2000, The language of covalent historic modifications, Nature, 403, 41, 10.1038/47412 Winston, 1999, The bromodomain: a chromatintargeting module?, Nat. Street. Biol., 6, 601, 10.1038/10640 Kingston, 1996, Repression and activation by multiprotein complexes that alter chromatin structure, Genes Dev., 10, 905, 10.1101/gad.10.8.905 Rowley, 1998, The critical role of chromosomal translocations in human leukemias, Annu. Rev.Genet., 32, 495, 10.1146/annurev.genet.32.1.495 Yu, 1998, MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis, 95, 10632 Shikama, 1997, The p300/CBP family: Integrating signals with transcription factors and chromatin, Trends Cell Biol., 7, 230, 10.1016/S0962-8924(97)01048-9 Ernst, 2001, MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein, Mol. Cell. Biol., 21, 2249, 10.1128/MCB.21.7.2249-2258.2001 Borrow, 1996, The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREBbinding protein, Nat. Genet., 14, 33, 10.1038/ng0996-33 Panagopoulos, 2001, Fusion of the MORT and CEP genes in acute myeloid leukemia with the t(10; 16) (q22;p13), Hum. Mol. Genet., 10, 395, 10.1093/hmg/10.4.395 Sterner, 2000, Acetylation of histories and transcription-related factors, Microbiol. Mol. Biol. Rev., 64, 435, 10.1128/MMBR.64.2.435-459.2000 Voegel, 1998, The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways, EMBO J., 17, 507, 10.1093/emboj/17.2.507 Akhtar, 2001, The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition, EMBO Rep., 2, 113, 10.1093/embo-reports/kve022 Chambon, 1996, A decade of molecular biology of retinoic acid receptors, FASEB J., 10, 940, 10.1096/fasebj.10.9.8801176 Alland, 1997, Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression, Nature, 387, 49, 10.1038/387049a0 Nagy, 1997, Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase, Cell, 89, 373, 10.1016/S0092-8674(00)80218-4 Heinzel, 1997, A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression, Nature, 387, 43, 10.1038/387043a0 Ayer, 1999, Histone deacetylases: transcriptional repression with SINers and NuRDs, Trends Cell Biol., 9, 193, 10.1016/S0962-8924(99)01536-6 Harbour, 2000, The Rb/E2F pathway: Expanding roles and emerging paradigms, Genes Dev., 14, 2393, 10.1101/gad.813200 Nagy, 1999, Mechanism of corepressor binding and release from nuclear hormone receptors, Genes Dev., 13, 3209, 10.1101/gad.13.24.3209 Zhang, 1999, A novel role for helix 12 of retinoid X receptor in regulating repression, Mol. Cell. Biol., 19, 6448, 10.1128/MCB.19.9.6448 Grignani, 1998, Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia, Nature, 391, 815, 10.1038/35901 Lin, 1998, Role of the histone deacetylase complex in acute promyelocytic leukaemia, Nature, 391, 811, 10.1038/35895 Lin, 2000, Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers, Mol. Cell, 5, 821, 10.1016/S1097-2765(00)80322-6 Melnick, 1999, Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia, Blood, 93, 3167, 10.1182/blood.V93.10.3167.410k44_3167_3215 Minucci, 2000, Oligomerization of RAR and AMLI transcription factors as a novel mechanism of oncogenic activation, Mol. Cell, 5, 811, 10.1016/S1097-2765(00)80321-4 Minucci, 2001, Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias?, Oncogene, 20, 3110, 10.1038/sj.onc.1204336 McKinsey, 2000, Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation, Nature, 408, 106, 10.1038/35040593 Bird, 1999, Methylation-induced repression — belts, braces, and chromatin, Cell, 99, 451, 10.1016/S0092-8674(00)81532-9 Rountree, 2000, DNMTI binds HDAC2 and a new corepressor, DMAP1, to form a complex at replication foci, Nat. Genet., 25, 269, 10.1038/77023 Fuks, 2000, DNA methyltransferase Dnmtl associates with histone deacetylase activity, Nat. Genet., 24, 88, 10.1038/71750 Fuks, 2001, Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription, EMBO J., 20, 2536, 10.1093/emboj/20.10.2536 Baylin, 1998, Alterations in DNA methylation: a fundamental aspect of neoplasia, Adv.Cancer Res., 72, 141, 10.1016/S0065-230X(08)60702-2 Jones, 1999, Cancer epigenetics comes of age, Nat. Genet., 21, 163, 10.1038/5947 Versteege, 1998, Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer, Nature, 394, 203, 10.1038/28212 Sevenet, 1999, Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers, Am. J. Hum. Genet., 65, 1342, 10.1086/302639 Shastry, 1984, Altered levels of a 5 S gene-specific transcription factor (TFIIIA) during ongenesis and embryonic development of Xenopus laevis, J. Biol. Chem., 259, 11373, 10.1016/S0021-9258(18)90871-9 Wong, 2000, BRGI, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines, Cancer Res., 60, 6171 Zhang, 2000, Exit from GI and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF, Cell, 101, 79, 10.1016/S0092-8674(00)80625-X Bochar, 2000, BRCAI is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer, Cell, 102, 257, 10.1016/S0092-8674(00)00030-1 Cheng, 1999, c-MYC interacts with INI1/hSNFS and requires the SWI/SNF complex for transactivation function, Nat. Genet., 22, 102, 10.1038/8811