Embedded health service development and research: why and how to do it (a ten-stage guide)

Health Research Policy and Systems - Tập 16 - Trang 1-8 - 2018
John Walley1, Mohammad Amir Khan2, Sophie Witter3, Rumana Haque4, James Newell1, Xiaolin Wei5
1Leeds Institute of Health Sciences, University of Leeds, England, United Kingdom
2Association for Social Development, Islamabad, Pakistan
3Institute for Global Health and Development, Queen Margaret University Edinburgh, Musselburgh, United Kingdom
4University of Dhaka, Dhaka, Bangladesh
5Dalla Lana School of Public Health, University of Toronto, Toronto, Canada

Tóm tắt

In a world of changing disease burdens, poor quality care and constrained health budgets, finding effective approaches to developing and implementing evidence-based health services is crucial. Much has been published on developing service tools and protocols, operational research and getting policy into practice but these are often undertaken in isolation from one another. This paper, based on 25 years of experience in a range of low and middle income contexts as well as wider literature, presents a systematic approach to connecting these activities in an embedded development and research approach. This approach can circumvent common problems such as lack of local ownership of new programmes, unrealistic resource requirements and poor implementation. We lay out a ten-step process, which is based on long-term partnerships and working within local systems and constraints and may be tailored to the context and needs. Service development and operational research is best prioritised, designed, conducted and replicated when it is embedded within ministry of health and national programmes. Care packages should from the outset be designed for scale-up, which is why the piloting stage is so crucial. In this way, the resulting package of care will be feasible within the context and will address local priorities. Researchers must be entrepreneurial and responsive to windows of funding for scale-up, working in real-world contexts where funding and decisions do not wait for evidence, so evidence generation has to be pragmatic to meet and ensure best use of the policy and financing cycles. The research should generate tested and easily usable tools, training materials and processes for use in scale-up. Development of the package should work within and strengthen the health system and other service delivery strategies to ensure that unintended negative consequences are minimised and that the strengthened systems support quality care and effective scale up of the package. While embedded development and research is promoted in theory, it is not yet practiced at scale by many initiatives, leading to wasted resources and un-sustained programmes. This guide presents a systematic and practical guide to support more effective engagements in future, both in developing interventions and supporting evidence-based scale-up.

Tài liệu tham khảo

United Nations. Sustainable development goals. 2015; Available at: https://sustainabledevelopment.un.org/sdgs. World Health Organisation. WHO handbook for guideline development. 2012. Peters D, Tran N, Adam T. Implementation research in health: a practical guide. 2013. Chew S, Armstrong N, Martin G. Institutionalising knowledge brokering as a sustainable knowledge translation solution in healthcare: how can it work in practice? Evid Policy. 2013;9:335–51. Bornbaum C, Kornas K, Peirson L, et al. Exploring the function and effectiveness of knowledge brokers as facilitators of knowledge translation in health-related settings: a systematic review and thematic analysis. Implement Sci. 2015;10:162. Ward V, House A, Hamer S. Knowledge brokering: the missing link in the evidence to action chain? Evid Policy. 2009;5:267–79. Walley J, Khan A, Karam Shah S, Witter S, Wei X. How to get research into practice: first get practice into research. WHO Bull. 2007;85:6. Walley J, Graham K, Wei X, Kain K, Weston R. Getting research into practice: primary care management of noncommunicable diseases in low- middle-income countries. WHO Bull. 2010;90(6):401–76. Soper B, Yaqub O, Hinrichs S, et al. CLAHRCs in practice: combined knowledge transfer and exchange strategies, cultural change, and experimentation. J Health Serv Res. 2013;18:53–64. Vindrola-Padros C, Pape T, Utley M, Fulop N. The role of embedded research in quality improvement: a narrative review. BMJ Qual Saf. 2017;26:70–80. Yamey G. What are the barriers to scaling up health interventions in low and middle income countries? A qualitative study of academic leaders in implementation science. Glob Health. 2012;8:11. Walley J, Wright J, editors. Public Health: an action guide to improving health. 2nd ed. Oxford: Oxford University Press; 2010. Hu Y, Walley J, Chou J, et al. Interventions to reduce childhood antibiotic prescribing for upper respiratory infections: systematic review and meta-analysis. J Epidemiol Community Health. 2016;7012 https://doi.org/10.1136/jech-2015-206543. Yin J, Yuan J, Hu Y, Wei X. Association between directly observed therapy and treatment outcomes in multidrug-resistant tuberculosis: a systematic review and meta-analysis. PLoS One. 2016;11(3):e0150511. World Health Organization, UNICEF. IMCI adaptation guide. Geneva: World Health Organisation; 2002. Khan S, Khan M, Owais S, et al. Formative research for delivering early child development care at private clinics in poor urban localities of Punjab, Pakistan. Sci Int. 2016;28(3):3131–4. Khan A, Walley J, Newell J, Imdad N. Tuberculosis in Pakistan: socio-cultural constraints and opportunities in treatment. Soc Sci Med. 2000;50(2):247–54. Zou G, Wei X, Gong W, et al. Evaluation of a systematic cardiovascular disease risk reduction strategy in primary healthcare: an exploratory study from Zhejiang, China. J Public Health. 2014;37(2):241–50. Grimshaw J, Eccles M, Lavis J, Hill S, Squires J. Knowledge translation of research findings. Implement Sci. 2012;7:50. Wei X, Walley J, Liang X, Liu F, Zhang X, Li R. Adapting a generic tuberculosis control operational guideline and scaling it up in China: a qualitative case study. BMC Public Health. 2008;8:260. Wei X, Zhang Z, Walley J, et al. Effect of a training and educational intervention for physicians and caregivers on antibiotic prescribing for upper respiratory tract infections in children at primary care facilities in rural China: a cluster-randomised controlled trial. Lancet Glob Health. 2017;5(12):e1258–67. Kliner M, Knight A, Elston J, Humphreys C, Mamvura C, Wright J, et al. Developing and testing models of TB contact tracing in rural southern Africa. Public Health Act. 2013;3(4):299–303. Hemming K, Haines T, Chilton P, Girling A, Lilford R. The stepped wedge cluster randomised trial: rationale, design, analysis, and reporting. Br Med J. 2015;350:h391. Siddiqi K, Khan A, Ahmad M, et al. Action to stop smoking in suspected tuberculosis (ASSIST) in Pakistan: a randomized controlled trial. Ann Intern Med. 2013;158(667):675. Khan A, Ahmed M, Anil S, et al. Strengthening the delivery of asthma and chronic obstructive pulmonary disease care at primary health care facilities: study design of a cluster randomized controlled trial in Pakistan. Glob Health Action. 2015;8:28225. Smith P, Morrow R, Ross D. The methodology of field trials of health interventions: a toolbox. Oxford: Oxford University Press; 2015. Walley J, Khan M, Newell J, Khan M. Effectiveness of the direct observation component of DOTS for tuberculosis: a randomised controlled trial in Pakistan. Lancet. 2001;357(9257):664–9. Humphreys C, Wright J, Walley J, et al. Nurse led, primary care based antiretroviral treatment versus hospital care: a controlled prospective study in Swaziland. BMC Health Serv Res. 2010;10:229. Khan M, Javed W, Ahmed M, et al. Delivering enhanced cardiovascular (hypertension) disease care through private health facilities in Pakistan. BMC Cardiovasc Disord. 2013;13:76. Kunutsor S, Walley J, Muchuro S, Katabira E, Balidawa H, Namagala E, et al. Improving adherence to antiretroviral therapy in sub-Saharan African HIV-positive populations: an enhanced adherence package. AIDS Care. 2012;24(10):1308–15. Huque R, Ahmed F, King R, et al. Improving the quality of care of children in community clinics: an intervention and evaluation in Bangladesh. Public Health Act. 2016;6(2):77–82. Khan M, Walley J, Witter S, Imran A, Safdar N. Costs and cost-effectiveness of different DOT strategies for the treatment of tuberculosis in Pakistan. Health Policy Plan. 2002;17(2):178–86. Zou G, Wei X, Witter S, Yin J, Walley J, Liu S, et al. Incremental cost-effectiveness of improving treatment results among migrant tuberculosis patients in Shanghai. Int J Tuberc Lung Dis. 2013;17(8):1056–64. Moore G, Audrey S, Barker M, et al. Process evaluation of complex interventions: Medical Research Council guidance. Br Med J. 2015;350:h1248. Khan MA, Owais S, Ishaq S, et al. Process evaluation of integrated early child development care at private clinics in poor urban Pakistan: a mixed methods study. BJBP. 2017;6 Khan MA, Munir MA, Anil S, et al. Structured performance monitoring of TB-care at facility, district and province levels - Pakistan experience. J Pak Med Assoc. 2016;66(4):418–24. Gagliardi A, Webster F, Brouwers M, et al. How does context influence collaborative decision-making for health services planning, delivery and evaluation? BMC Health Serv Res. 2014;14:545.