Eliminating residual iPS cells for safety in clinical application

Shigeo Masuda1, Shigeru Miyagawa1, Satsuki Fukushima1, Nagako Sougawa1, Kaori Okimoto1, Tada Chika1, Atsuhiro Saito1, Yoshiki Sawa1
1Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 565-0871, Osaka, Japan

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Huskey NE et al (2015) CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation. Stem Cell Rep 4:374–389

Masuda S et al (2014) Emerging innovation towards safety in the clinical application of ESCs and iPSCs. Nat Rev Cardiol 11:553–554

Tateno H et al (2011) Glycome diagnosis of human induced pluripotent stem cells using lectin microarray. J Biol Chem 286:20345–20353

Tateno H et al (2015) Elimination of tumorigenic human pluripotent stem cells by a recombinant lectin-toxin fusion protein. Stem Cell Rep. doi: 10.1016/j.stemcr.2015.02.016

Wu T, Pinto HB, Kamikawa YF, Donohoe ME (2015) The BET family member BRD4 interacts with OCT4 and regulates pluripotency gene expression. Stem Cell Rep 4:390–403