Electrophysiological Correlates of Attentional Disorders in 12- to 13-Year-Old Adolescents
Tóm tắt
The EEG was recorded in 12- to 13-year-old adolescents with attention deficit hyperactivity disorder (ADHD). During the EEG recording, the subjects performed an attention test. Pairs of tone stimuli in the combinations low–low and low–high were presented in random order with equal probabilities with intervals of 2.3 s. Subjects had to press a button as soon as possible in response to low–low tone pair presentation (a go trial) and not to press the button when a pair consisting of low and high tones was presented (a no-go trial). On the basis of the results of the test performance (the numbers of omissions and false alarms), the subjects were divided into three groups characterized by the degree of severity of the attentional disorder. The evoked potentials in go and no-go trials were detected individually for the subject groups and each derivation. The components N1, N2, P2, P3-go, and P3-no-go were identified in the evoked potentials. These components had different latencies and were differently localized over the head surface. Only the amplitudes of P3-go and P3-no-go in the subjects were statistically significantly correlated with the severity of the attentional disorder.
Tài liệu tham khảo
Badalyan, L.O., Zavadenko, N.N., and Uspenskaya, T.Yu., Syndromes of Attention Deficit in Children, Obozrenie Psikhiatr. Med. Psikhol. im. V.M. Bekhtereva, 1993, no. 3, p. 74.
Monastra, V., Linden, M., Green, G., et al., Assessing Attention Deficit Hyperactivity Disorder via Quantitative Electroencephalography: An Initial Validation Study, Neuropsychology, 1999, vol. 13, no. 3, p. 424
Wender, P. and Shader, R., Syndrome of Attention Deficit with Hyperactivity, in Psychiatry, Shader, R.I., Ed., n. p., n. d. Translated under the title Psikhiatriya, Sheider, R., Ed., Moscow: Praktika, 1998.
Goldman, L.S., Genel, M., Bezman, R.J., and Slanetz, P.J., Diagnosis and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents, JAMA, 1998, vol. 279, no. 14, p. 1100.
Kytja, K.S. and Voeller, G.R., Toward a Neurobiologic Nosology of Attention Deficit Hyperactivity Disorder, J. Child Neurol., 1991, vol. 6, p. 2.
Satterfield, J.H., Schell, A., Nicholas, T., and Backs, R.W., Topographic Study of Auditory Event-related Potentials in Normal Boys and Boys with Attention Deficit Disorder with Hyperactivity, Psychophysiology, 1988, vol. 25, no. 5, p. 591.
Karayanidis, F., Robaey, P., Bourassa, M., et al., ERP Differences in Visual Attention Processing between Attention-Deficit Hyperactivity Disorder and Control Boys in the Absence of Performance Differences, Psychophysiology, 2000, vol. 37, p. 319.
Linden, M., Gevirtz, R., Isenhart, R., and Fischer, T., Event-related Potentials of Subgroups of Children with Attention Deficit Hyperactivity Disorder and the Implications for EEG Biofeedback, J. Neurotherapy, 1996, vol. 1, p. 1.
Satterfield, J.H., Schell, A., Nicholas, T., et al., Ontogeny of Selective Attention Effects on Event-related Potentials in Attention Deficit Hyperactivity Disorder and Normal Boys, Biol. Psychiat., 1990, vol. 28, p. 879.
Jonkman, L., Kemner, C., Verbaten, M., et al., Attentional Capacity, a Probe ERP Study: Difference between Children with Attention-Deficit Hyperactivity Disorder and Normal Control Children and Effects of Methylphenidate, Psychophysiology, 2000, vol. 37, p. 334.
Kropotov, Yu.D., The Role of Striatum in the Action Selection, Fiziol. Zh. SSSR im. I.M. Sechenova, 1997, vol. 83, no. 1, p. 45.
Kropotova, O.V., Ponomarev, V.A., Nechaev, V.B., et al., Components of the Action Suppression in the Brain Evoked Potentials in Adolescents, Fiziol. Chel., 1998, vol. 24, no. 2, p. 23.
Roberts, L.E., Rau, H., Lutzenberger, W., and Birbaumer, N., Mapping P300 onto Inhibition: Go/NoGo Discrimination, Electroencephalogr. Clin. Neurophysiol., 1994, vol. 92, no. 1, p. 93.
LaHoste, G.L., Swanson, J.M., and Wigal, S.W., Dopamine D4 Receptor Gene Polymorphism Is Associated with Attention Deficit Hyperactivity Disorder, Molecular Psychiat., 1996, vol. 1, p.121.
Riccio, C., Hynd, G., Cohen, M., and Gonzalez, J., Neurological Basis of Attention Deficit Hyperactivity Disorder, Exceptional Children., 1993, vol. 60, no. 2, p. 118.
Satterfield, J.H., EEG Issues in Children with Minimal Brain Dysfunction, Seminars in Psychiatry, 1973, vol. 5, no. 1, p. 35.
Swanson, J., Castellanos, F.X., Myrias, M., et al., Cognitive Neuroscience of Attention Deficit Hyperactivity Disorder and Hyperkinetic Disorder, Cognit. Neurosci., 1998, vol. 8, p. 263.
Swanson, J., Sergeant, J., Taylor, E., et al., Attention Deficit Hyperactivity Disorder and Hyperkinetic Disorder, Lancet, 1998, vol. 351, p. 429.
Kropotova, O.V., Neurophysiological Correlates of Selective Attention, Action Selection, and Their Disorders at the Attention Deficit Hyperactivity Syndrome in a Man, Cand. Sci. (Biol.) Dissertation, St. Petersburg, 1998.
Diagnostic and Statistical Manual of Mental Disorder, Washington: Am. Pshych. Assoc., 1994.
Swanson, J.M., School-based Assessments and Interventions for ADD Students, Irvine: K.C. Publishing, 1992.
Greenberg, L. and Waldmant, I., Developmental Normative Data on the Test of Variables of Attention (T.O.V.A.), Child Psychiatry, 1993, vol. 34, no. 6, p. 1019.
Naatanen, R., Attention and Brain Functions. Translated under the title Vnimanie i funktsii mozga: uchebnoe posobie, Sokolov, E.N., Ed., Moscow: Mosk. Gos. Univ., 1998.
Falkenstein, M., Koshlykova, N.A., Kiroj, V.N., et al., Late ERP Components in Visual and Auditory Go/Nogo Tasks, Electroencephalogr. Clin. Neurophysiol., 1995, vol. 96, p. 36.