Electronic feature extractor for action potentials
Tóm tắt
An electronic feature-extraction system is presented that simplifies the measurement of five parameters of the action potential. These parameters are: (a) the peak amplitude of the action potential, (b) the maximum slope, (c) the threshold as measured at the inflection on the rising phase of the action potential, (d) the time interval between the inflection and the peak of the action potential, and (e) the time constant of the ‘exponentially’ rising foot of the action potential. Using this equipment, the foot of the action potential was found in the squid giant axon to be close to a pure exponential only at temperatures less than 15° C.
Tài liệu tham khảo
Donati F. andKunov H. (1976) A model for studying velocity variations in unmyelinated axons.IEEE Trans. BME-23, 23.
Freygang, W. H. Jun, Rapoport, S. I. andPeachey, L. D. (1967) Some relations between changes in the linear electrical properties of striated muscle fibres and changes in ultrastructure.J. Gen. Physiol.,50, 2437–2458.
Hodgkin, A. L. andNakajima, S. (1972) Analysis of the membrane capacity in frog muscle.J. Physiol.,221, 121.
Rissman, P. (1977) The leading edge approximation to the nerve axon problem.Bull. Math. Biol.,39, 43.
Tasaki, I. andHagiwara, S. (1957) Capacity of muscle fibre membrane.Am. J. Physiol.,188, 432–459.
Wait, J. V., Huelsman, L. P. andKorn, G. A. (1975)Introduction to operational amplifier theory and applications, McGraw Hill.
Westerfield, M., Moore, J. W., Ramon, F. andJoyner, R. (1976) Squid axons as a model for the effects of neuron geometry.Biophys. J. 16, 79a.