Electrochemical reaction mechanism of phenacetin at a carboxylated multiwall carbon nanotube modified electrode and its analytical applications

Chemical Research in Chinese Universities - Tập 30 - Trang 905-909 - 2014
Jinlei Zhang1, Cuiling Lan1, Bingfang Shi1, Fang Liu1, Dandan Zhao1, Xuecai Tan2
1Department of Chemistry and Life Science, Baise University, Baise, P. R. China
2School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning, P.R. China

Tóm tắt

A novel type of carboxylated multiwalled carbon nanotube modified electrode(c-MWCNTs/GCE) was constructed and the electrochemical properties of phenacetin(PHE) at it were studied. In a buffer solution of 0.1 mol/L HAc-NaAc(pH=5.3), PHE exhibited a couple of quasi-reversible redox peaks and an anodic peak in the potential range of 0.2–1.2 V at c-MWCNTs/GCE. The peak current was proportional to the concentration of PHE in the range of 4.0×10−6–1.0×10−4 mol/L with a detection limit of 1.0×10−6 mol/L(S/N=3). The c-MWCNTs/GCE showed excellent repeatability and stability and the electrochemical reaction mechanism of PHE was proposed. This method was used to determine the content of PHE in medical tablets and the recovery was determined to be 96.5%–104.2% by means of a standard addition method.

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