Electro/magnetoencephalographic signatures of human brain insulin resistance

WHO, 2014 Long, 2016, The Framingham Heart Study – 67 years of discovery in metabolic disease, Nat Rev Endocrinol, 12, 177, 10.1038/nrendo.2015.226 Haslam, 2005, Obesity, Lancet, 366, 1197, 10.1016/S0140-6736(05)67483-1 Font-Burgada, 2016, Obesity and cancer: the oil that feeds the flame, Cell Metab, 23, 48, 10.1016/j.cmet.2015.12.015 Speakman, 2013, Evolutionary perspectives on the obesity epidemic: adaptive, maladaptive, and neutral viewpoints, Annu Rev Nutr, 33, 289, 10.1146/annurev-nutr-071811-150711 Seaquist, 2001, The effect of insulin on in vivo cerebral glucose concentrations and rates of glucose transport/metabolism in humans, Diabetes, 50, 2203, 10.2337/diabetes.50.10.2203 Havrankova, 1978, Insulin receptors are widely distributed in the central nervous system of the rat, Nature, 272, 827, 10.1038/272827a0 2011 2014 Baura, 1993, Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain, J Clin Invest, 92, 1824, 10.1172/JCI116773 Kullmann, 2015, Insulin action in the human brain: evidence from neuroimaging studies, J Neuroendocrinol, 27, 419, 10.1111/jne.12254 Bruning, 2000, Role of brain insulin receptor in control of body weight and reproduction, Science, 289, 2122, 10.1126/science.289.5487.2122 Schlogl, 2016 Heni, 2015, Impaired insulin action in the human brain: causes and metabolic consequences, Nat Rev Endocrinol, 11, 701, 10.1038/nrendo.2015.173 Born, 2002, Sniffing neuropeptides: a transnasal approach to the human brain, Nat Neurosci, 5, 514, 10.1038/nn0602-849 Heni, 2014, Central insulin administration improves whole-body insulin sensitivity via hypothalamus and parasympathetic outputs in men, Diabetes, 63, 4083, 10.2337/db14-0477 Kullmann, 2013, Intranasal insulin modulates intrinsic reward and prefrontal circuitry of the human brain in lean women, Neuroendocrinology, 97, 176, 10.1159/000341406 Seaquist, 2007, Insulin reduces the BOLD response but is without effect on the VEP during presentation of a visual task in humans, J Cereb Blood Flow Metab, 27, 154, 10.1038/sj.jcbfm.9600316 Benedict, 2006, Effect of insulin on the brain activity obtained during visual and memory tasks in healthy human subjects, Neuroendocrinology, 83, 20, 10.1159/000093338 Kern, 1999, Central nervous system effects of intranasally administered insulin during euglycemia in men, Diabetes, 48, 557, 10.2337/diabetes.48.3.557 Hallschmid, 2004, Transcortical direct current potential shift reflects immediate signaling of systemic insulin to the human brain, Diabetes, 53, 2202, 10.2337/diabetes.53.9.2202 Tschritter, 2006, The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study, Proc Natl Acad Sci U S A, 103, 12103, 10.1073/pnas.0604404103 Tschritter, 2009, Insulin effects on beta and theta activity in the human brain are differentially affected by ageing, Diabetologia, 52, 169, 10.1007/s00125-008-1187-5 Tschritter, 2007, Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans, Diabetologia, 50, 2602, 10.1007/s00125-007-0839-1 Ketterer, 2014, Polymorphism rs3123554 in CNR2 reveals gender-specific effects on body weight and affects loss of body weight and cerebral insulin action, Obesity (Silver Spring), 22, 925, 10.1002/oby.20573 Tschritter, 2011, An obesity risk SNP (rs17782313) near the MC4R gene is associated with cerebrocortical insulin resistance in humans, J Obes, 2011, 283153, 10.1155/2011/283153 Tschritter, 2007, Cerebrocortical beta activity in overweight humans responds to insulin detemir, PLoS ONE, 2, e1196, 10.1371/journal.pone.0001196 Hennige, 2006, Tissue selectivity of insulin detemir action in vivo, Diabetologia, 49, 1274, 10.1007/s00125-006-0192-9 Hallschmid, 2010, Euglycemic infusion of insulin detemir compared with human insulin appears to increase direct current brain potential response and reduces food intake while inducing similar systemic effects, Diabetes, 59, 1101, 10.2337/db09-1493 Tschritter, 2012, High cerebral insulin sensitivity is associated with loss of body fat during lifestyle intervention, Diabetologia, 55, 175, 10.1007/s00125-011-2309-z Stingl, 2010, Insulin modulation of magnetoencephalographic resting state dynamics in lean and obese subjects, Front Syst Neurosci, 4, 157, 10.3389/fnsys.2010.00157 Ungerleider, 1994, ‘What’ and ‘where’ in the human brain, Curr Opin Neurobiol, 4, 157, 10.1016/0959-4388(94)90066-3 Thorpe, 2001, Neuroscience. Seeking categories in the brain, Science, 291, 260, 10.1126/science.1058249 Toepel, 2009, The brain tracks the energetic value in food images, Neuroimage, 44, 967, 10.1016/j.neuroimage.2008.10.005 Stockburger, 2009, The impact of hunger on food cue processing: an event-related brain potential study, Neuroimage, 47, 1819, 10.1016/j.neuroimage.2009.04.071 Stingl, 2010, The temporal sequence of magnetic brain activity for food categorization and memorization – an exploratory study, Neuroimage, 52, 1584, 10.1016/j.neuroimage.2010.04.278 Bielser, 2015, Does my brain want what my eyes like? – How food liking and choice influence spatio-temporal brain dynamics of food viewing, Brain Cogn Guthoff, 2011, The insulin-mediated modulation of visually evoked magnetic fields is reduced in obese subjects, PLoS ONE, 6, e19482, 10.1371/journal.pone.0019482 Preissl, 2004, Fetal magnetoencephalography: current progress and trends, Exp Neurol, 190, S28, 10.1016/j.expneurol.2004.06.016 Linder, 2014, Maternal insulin sensitivity is associated with oral glucose-induced changes in fetal brain activity, Diabetologia, 57, 1192, 10.1007/s00125-014-3217-9 Linder, 2015, Gestational diabetes impairs human fetal postprandial brain activity, J Clin Endocrinol Metab, 100, 4029, 10.1210/jc.2015-2692 Kullmann, 2015, Selective insulin resistance in homeostatic and cognitive control brain areas in overweight and obese adults, Diabetes Care, 38, 1044, 10.2337/dc14-2319 Kullmann, 2014, Resting-state functional connectivity of the human hypothalamus, Hum Brain Mapp, 35, 6088, 10.1002/hbm.22607 Patel, 2005, Characterization of N200 and P300: selected studies of the event-related potential, Int J Med Sci, 2, 147, 10.7150/ijms.2.147 Nieuwenhuis, 2005, Decision making, the p3, and the locus coeruleus-norepinephrine system, Psychol Bull, 131, 510, 10.1037/0033-2909.131.4.510 2011 van Diessen, 2015, Opportunities and methodological challenges in EEG and MEG resting state functional brain network research, Clin Neurophysiol, 126, 1468, 10.1016/j.clinph.2014.11.018 Bigdely-Shamlo, 2016, Preparing laboratory and real-world EEG data for large-scale analysis: a containerized approach, Front Neuroinform, 10, 7, 10.3389/fninf.2016.00007 Stingl, 2012, Neuronal correlates of reduced memory performance in overweight subjects, Neuroimage, 60, 362, 10.1016/j.neuroimage.2011.12.012