Eficacia a medio y largo plazo de la ventilación no invasiva en el síndrome de hipoventilación-obesidad (estudio Pickwick)

2000 Tulaimat, 2014, Defining obesity hypoventilation syndrome, Thorax., 69, 491, 10.1136/thoraxjnl-2013-204992 Nowbar, 2004, Obesity-associated hypoventilation in hospitalized patients: Prevalence, effects, and outcome, Am J Med, 116, 1, 10.1016/j.amjmed.2003.08.022 Lloberes, 2011, Diagnóstico y tratamiento del síndrome de apneas-hipopneas del sueño, Arch Bronconeumol., 47, 143 Olson, 2005, The obesity hypoventilation syndrome, Am J Med., 118, 948, 10.1016/j.amjmed.2005.03.042 Berger, 2001, Obesity hypoventilation syndrome as a Spectrum of respiratory disturbances during sleep, Chest., 120, 1231, 10.1378/chest.120.4.1231 Ayappa, 2002, Hypercapnia and ventilatory periodicity in obstructive sleep apnea syndrome, Am J Respir Crit Care Med., 166, 1112, 10.1164/rccm.200203-212OC Piper, 2008, Randomised trial of CPAP vs bilevel support in the treatment of obesity hypoventilation syndrome without severe nocturnal desaturation, Thorax., 63, 395, 10.1136/thx.2007.081315 Borel, 2012, Noninvasive ventilation in mild obesity hypoventilation syndrome. A randomized controlled trial, Chest, 141, 692, 10.1378/chest.10-2531 Berg, 2001, The use of health-care resources in obesity-hypoventilation syndrome, Chest., 120, 377, 10.1378/chest.120.2.377 Masa, 2001, The obesity hypoventilation syndrome can be treated with noninvasive mechanical ventilation, Chest., 119, 1102, 10.1378/chest.119.4.1102 Masa, 2015, Spanish Sleep Network. Efficacy of different treatment alternatives for obesity hypoventilation syndrome. Pickwick study, Am J Respir Crit Care Med., 192, 86, 10.1164/rccm.201410-1900OC Ip, 2000, Serum leptin and vascular risk factors in obstructive sleep apnea, Chest., 118, 580, 10.1378/chest.118.3.580 Phipps, 2002, Association of serum leptin with hypoventilation in human obesity, Thorax., 57, 75, 10.1136/thorax.57.1.75 Yee, 2006, Treatment of obesity hypoventilation syndrome and serum leptin, Respiration., 73, 209, 10.1159/000088358 Redolfi, 2007, Long-term noninvasive ventilation increases chemosensitivity and leptin in obesity-hypoventilation syndrome, Respir Med., 101, 1191, 10.1016/j.rmed.2006.11.005 Royblat, 2000, Raised interleukin-6 levels in obese patients, Obes Res., 8, 673, 10.1038/oby.2000.86 Ortega Ruiz, 2014, Continuous home oxygen therapy, Arch Bronconeumol., 50, 185, 10.1016/j.arbres.2013.11.025