Efficient in vitro elicitation of β-carboline alkaloids in transformed root cultures of Peganum harmala

El-Saad, 1980, Peganum harmala: its use in certain dermatoses, Int J Dermatol, 19, 221, 10.1111/j.1365-4362.1980.tb00305.x Al-Shama, 1981, Antimicrobial agents from higher plants. Antimicrobial agents from Peganum harmala seeds, J Nat Prod, 745, 10.1021/np50018a025 Wink M, Schmeller T, Latz-Bruning B. Modes of action of allelochemical alkaloids: interaction with neuroreceptors, DNA and other molecular targets. J Chem Ecol 1998;(11):1881–937. Wakabayashi, 1997, Human exposure to mutagenic/carcinogenic heterocyclic amines and comutagenic beta-carbolines, Mutat Res, 376, 253, 10.1016/S0027-5107(97)00050-X Picada, 1997, Genotoxic effects of structurally related beta-carboline alkaloids, Mutat Res, 379, 135, 10.1016/S0027-5107(97)00116-4 Bergstrom, 1997, 11C-harmine as a tracer for monoamine oxidase A (MAO-A): in vitro and in vivo studies, Nucl Med Biol, 24, 287, 10.1016/S0969-8051(97)00013-9 Rivas, 1999, Effects of some beta-carboline alkaloids on intact Trypanosoma cruzi epimastigotes, Comp Biochem Physiol C Pharmacol Toxicol Endocrinol, 122, 27, 10.1016/S0742-8413(98)10069-5 EI-Gengaihi, 1997, Chemical and biological investigation of harmala plant. 2. Alkaloidal investigation, J Appl Ent, 121, 165, 10.1111/j.1439-0418.1997.tb01387.x Albores, 1990, Mitochondrial respiratory inhibition by N-methylated β-carboline derivatives structurally resembling N-methyl-4-phenylpyridine, Proc Natl Acad Sci, 87, 9368, 10.1073/pnas.87.23.9368 Sobhani, 2002, An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta carboline alkaloid, J Pharm Pharm Sci, 5, 19 Khawar, 2005, Efficient shoot regeneration in Syrian Rue (Peganum harmala L.) under in vitro condition, Int J Agric Biol, 7, 790 Neha Goel, Narender Singh, Raman Saini. Efficient in vitro multiplication of Syrian Rue (Peganum harmala L.) using 6-benzylaminopurine pre-conditioned seedling explants. Nat Sci 2009;7(7):129–134. Kuzovkina N, Gohar A, Alterman E. Production of β-carboline Alkaloids in Transformed Root Cultures of Peganum hamala L. Z Naturforsch 1990;45c:727–8. Lloyd, 1980, Commercially feasible micro-propagation of mountain laurel, kalmia latifolia, by use of shoot tip culture, Int Plant Prop Soc Proc, 30, 420 Oono, 1993, Effects of the over-expression of the rolC gene on leaf development in transgenic periclinal chimeric plants, Plant Cell Physiol, 34, 745, 10.1093/oxfordjournals.pcp.a078478 Sawada, 1995, PCR detection of Ti and Ri plasmids from phytopathogenic Agrobacterium strains, Appl Environ Microbiol, 61, 828, 10.1128/AEM.61.2.828-831.1995 Neill, 2002, Hydrogen peroxide and nitric oxide as signaling molecules in plants, J Exp Bot, 53, 1237, 10.1093/jexbot/53.372.1237 Dai, 1995, Induction of nopaline syntheses promoter activity by H2O2 has no direct correlation with salicylic acid, Plant Physiol, 109, 1191, 10.1104/pp.109.4.1191 Zayed R, Wink M. β-Carboline and quinoline alkaloid in root culture and intact plants of Peganum harmala. Z Naturforsch 2005;60c:451–8. Berlin, 1993, Biosynthesis of serotonin and β-carboline alkaloids in hairy root cultures of Peganum harmala, Phytochemistry, 33, 587, 10.1016/0031-9422(93)85453-X Berlin J, Kuzovkina N, Ruegenhagen C, Fecker L, Commandeur U, Wray V. Hairy root of Peganum harmala II. Characterization of cell lines and effect of culture conditions on the accumulation of β-carboline alkaloids and serotonin. Z Naturforsch 1992;47c:222–30.