Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus

Fuminori Sakurai1,2, Nobuhiro Narii1, Kyoko Tomita1, Shinsaku Togo3, Kazuhisa Takahashi3, Mitsuhiro Machitani1, Masashi Tachibana1, Masaaki Ouchi4, Nobuyoshi Katagiri4, Yasuo Urata4, Toshiyoshi Fujiwara5, Hiroyuki Mizuguchi1,6,7,8
1Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan
2Laboratory of Regulatory Sciences for Oligonucleotide Therapeutics, Clinical Drug Development Unit, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan
3Division of Respiratory Medicine, Juntendo University Faculty of Medicine & Graduate School of Medicine, Tokyo, Japan
4Oncolys Biopharma, Tokyo, Japan
5Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan
6The Center for Advanced Medical Engineering and Informatics, Osaka University, Osaka, Japan
7Laboratory of Hepatocyte Differentiation, National Institute of Biomedical Innovation, Osaka, Japan
8iPS Cell-Based Research Project on Hepatic Toxicity and Metabolism, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan

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