Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse
Tóm tắt
Từ khóa
Tài liệu tham khảo
Bonnerot, 1993, Clonal analysis in the intact mouse embryo by intragenic homologous recombination, C. R. Acad. Sci. Ser. III, 316, 1207
Brocard, 1997, Spatio-temporally controlled site-specific somatic mutagenesis in the mouse, Proc. Natl. Acad. Sci. USA, 94, 14559, 10.1073/pnas.94.26.14559
Danielian, 1998, Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase, Curr. Biol., 8, 1323, 10.1016/S0960-9822(07)00562-3
Danielian, 1993, Identification of residues in the estrogen receptor that confer differential sensitivity to estrogen and hydroxytamoxifen, Mol. Endocrinol., 7, 232
Fawell, 1990, Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor, Cell, 60, 953, 10.1016/0092-8674(90)90343-D
Feil, 1996, Ligand-activated site-specific recombination in mice, Proc. Natl. Acad. Sci. USA, 93, 10887, 10.1073/pnas.93.20.10887
Feil, 1997, Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains, Biochem. Biophys. Res. Commun., 237, 752, 10.1006/bbrc.1997.7124
Gaiano, 1999, A method for rapid gain-of-function studies in the mouse embryonic nervous system, Nat. Neurosci., 2, 812, 10.1038/12186
Gorman, 2000, Site-specific gene targeting for gene expression in eukaryotes, Curr. Opin. Biotechnol., 11, 455, 10.1016/S0958-1669(00)00127-0
Hogan, 1994
Imai, 2001, Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes, Proc. Natl. Acad. Sci. USA, 98, 224
Indra, 1999, Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases, Nucleic Acids Res., 27, 4324, 10.1093/nar/27.22.4324
Kimmel, 2000, Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation, Genes Dev., 14, 1377, 10.1101/gad.14.11.1377
Littlewood, 1995, A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins, Nucleic Acids Res., 23, 1686, 10.1093/nar/23.10.1686
Lobe, 1999, Z/AP, a double reporter for cre-mediated recombination, Dev. Biol., 208, 281, 10.1006/dbio.1999.9209
Mathis, 1997, Retrospective clonal analysis of the cerebellum using genetic laacZ/lacZ mouse mosaics, Development, 124, 4089, 10.1242/dev.124.20.4089
Mattioni, 1994, Regulation of protein activities by fusion to steroid binding domains, Methods Cell Biol., 43, 335, 10.1016/S0091-679X(08)60611-1
Nagy, 2000, Cre recombinase: The universal reagent for genome tailoring, Genesis, 26, 99, 10.1002/(SICI)1526-968X(200002)26:2<99::AID-GENE1>3.0.CO;2-B
Nagy, 2001, Chimaeras and mosaics for dissecting complex mutant phenotypes, Int. J. Dev. Biol., 45, 577
Niwa, 1991, Efficient selection for high-expression transfectants with a novel eukaryotic vector, Gene, 108, 193, 10.1016/0378-1119(91)90434-D
Picard, 1994, Regulation of protein function through expression of chimaeric proteins, Curr. Opin. Biotechnol., 5, 511, 10.1016/0958-1669(94)90066-3
Pratt, 2000, Embryonic stem cells and transgenic mice ubiquitously expressing a tau-tagged green fluorescent protein, Dev. Biol., 228, 19, 10.1006/dbio.2000.9935
Rossant, 1999, “Cre”-ating mouse mutants: A meeting review on conditional mouse genetics, Genes Dev., 13, 142, 10.1101/gad.13.2.142
Sadek, 1996, The effects of the antihormones RU486 and tamoxifen on fetoplacental development and placental bed vascularisation in the rat: A model for intrauterine fetal growth retardation, Br. J. Obstet. Gynaecol., 103, 630, 10.1111/j.1471-0528.1996.tb09830.x
Sanes, 1994, Lineage tracing. The laatest in lineaage, Curr. Biol., 4, 1162, 10.1016/S0960-9822(00)00264-5
Schwenk, 1998, Temporally and spatially regulated somatic mutagenesis in mice, Nucleic Acids Res., 26, 1427, 10.1093/nar/26.6.1427
Soriano, 1999, Generalized lacZ expression with the ROSA26 Cre reporter strain, Nat. Genet., 21, 70, 10.1038/5007
Vallier, 2001, An efficient system for conditional gene expression in embryonic stem cells and in their in vitro and in vivo differentiated derivatives, Proc. Natl. Acad. Sci. USA, 98, 2467, 10.1073/pnas.041617198
Vasioukhin, 1999, The magical touch: Genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin, Proc. Natl. Acad. Sci. USA, 96, 8551, 10.1073/pnas.96.15.8551
Vooijs, 2001, A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent, EMBO Rep., 2, 292, 10.1093/embo-reports/kve064
Whiting, 1991, Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression, Genes Dev., 5, 2048, 10.1101/gad.5.11.2048