Zhenyu Jiang1, Jianhua Wu1, Li Li, Xi‐Huai Chen1, Guoqiao Lai1, Jianxiong Jiang1, Yixin Lü2, Li‐Wen Xu1
1Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, 310012, P. R. China
2Department of Chemistry, National University of Singapore, Singapore 117543, Republic of Singapore
Tóm tắt
Abstract
Lewis acid-assisted Brønsted acid (LBA) catalysis was proposed for the iron-catalyzed Friedel-Crafts alkylation of indoles with chalcones. This proposal was supported by the ESI-MS and cyclic voltammetry. The addition of acac to the iron-catalyzed Friedel-Crafts alkylation of indoles with chalcones created a powerful catalytic system, which makes the alkylation reactions occur easily under mild conditions.
