Efficacy of repetitive transcranial magnetic stimulation in treatment-resistant depression: the evidence thus far

General Psychiatry - Tập 32 Số 4 - Trang e100074 - 2019
Aditya Somani1, Sujita Kumar Kar2
1Department of Psychiatry, Mental Health Institute, Chandigarh, India
2Department of Psychiatry, King George’s Medical University, Lucknow, Uttar Pradesh, India

Tóm tắt

Depression is a common mental disorder, which attributes to significant morbidity, disability and burden of care. A significant number of patients with depression still remain symptomatic after adequate trials of antidepressant treatment as well as psychotherapy, which is often referred to as treatment-resistant depression. Neuromodulation techniques—like electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation, may be useful augmenting techniques in depression, mostly recommended for treatment-resistant cases. Robust evidence exists regarding the efficacy of electroconvulsive therapy in the management of treatment-resistant depression; however, other techniques are understudied. TMS has been increasingly studied in various psychiatric disorders including depression. It has been approved by the US Food and Drug Administration for use in major depressive disorder. Over the past two decades, TMS has been studied in diverse groups of the population with depression using several research designs. This article gives an overview of the efficacy of repetitive TMS in treatment-resistant depression with the recent evidence.

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Tài liệu tham khảo

WHO Fact Sheet on Depression . Secondary who fact sheet on depression, 2018. Available: http://www.who.int/news-room/fact-sheets/detail/depression

Cipriani, 2011, Depression in adults: drug and physical treatments, BMJ Clin Evid, 2011

Pradhan, 2015, Ketamine, transcranial magnetic stimulation, and depression specific yoga and mindfulness based cognitive therapy in management of treatment resistant depression: review and some data on efficacy, Depress Res Treat, 2015, 1, 10.1155/2015/842817

Mrazek, 2014, A review of the clinical, economic, and societal burden of treatment-resistant depression: 1996–2013, PS, 65, 977, 10.1176/appi.ps.201300059

Guo, 2017, Updated review on the clinical use of repetitive transcranial magnetic stimulation in psychiatric disorders, Neurosci Bull, 33, 747, 10.1007/s12264-017-0185-3

Klomjai, 2015, Basic principles of transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS), Ann Phys Rehabil Med, 58, 208, 10.1016/j.rehab.2015.05.005

Machado, 2013, Repetitive transcranial magnetic stimulation for clinical applications in neurological and psychiatric disorders: an overview, EAJM, 45, 191, 10.5152/eajm.2013.39

Barker, 1985, Non-Invasive magnetic stimulation of human motor cortex, The Lancet, 325, 1106, 10.1016/S0140-6736(85)92413-4

Chen, 1997, Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation, Neurology, 48, 1398, 10.1212/WNL.48.5.1398

Chung, 2015, Theta-burst stimulation: a new form of TMS treatment for depression?, Depress Anxiety, 32, 182, 10.1002/da.22335

Huang, 2005, Theta burst stimulation of the human motor cortex, Neuron, 45, 201, 10.1016/j.neuron.2004.12.033

Blumberger, 2018, Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial, The Lancet, 391, 1683, 10.1016/S0140-6736(18)30295-2

Grimm, 2008, Imbalance between left and right dorsolateral prefrontal cortex in major depression is linked to negative emotional judgment: an fMRI study in severe major depressive disorder, Biol Psychiatry, 63, 369, 10.1016/j.biopsych.2007.05.033

George, 2000, A controlled trial of daily left prefrontal cortex TMS for treating depression, Biol Psychiatry, 48, 962, 10.1016/S0006-3223(00)01048-9

Klein, 1999, Therapeutic efficacy of right prefrontal slow repetitive transcranial magnetic stimulation in major depression, Arch Gen Psychiatry, 56, 315, 10.1001/archpsyc.56.4.315

Kedzior, 2015, Durability of the antidepressant effect of the high-frequency repetitive transcranial magnetic stimulation (rTMS) in the absence of maintenance treatment in major depression: a systematic review and meta-analysis of 16 double-blind, randomized, SHAM-CONTR, Depress Anxiety, 32, 193, 10.1002/da.22339

Berlim, 2013, Clinically meaningful efficacy and acceptability of low-frequency repetitive transcranial magnetic stimulation (rTMS) for treating primary major depression: a meta-analysis of randomized, double-blind and sham-controlled trials, Neuropsychopharmacology, 38, 543, 10.1038/npp.2012.237

Berlim, 2014, Response, remission and drop-out rates following high-frequency repetitive transcranial magnetic stimulation (rTMS) for treating major depression: a systematic review and meta-analysis of randomized, double-blind and sham-controlled trials, Psychol Med, 44, 225, 10.1017/S0033291713000512

Chen, 2013, Left versus right repetitive transcranial magnetic stimulation in treating major depression: a meta-analysis of randomised controlled trials, Psychiatry Res, 210, 1260, 10.1016/j.psychres.2013.09.007

Gaynes, 2014, Repetitive transcranial magnetic stimulation for treatment-resistant depression: a systematic review and meta-analysis, J Clin Psychiatry, 75, 477, 10.4088/JCP.13r08815

Wei, 2017, Meta-Analysis of the efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression, Shanghai Arch Psychiatry, 29, 328

Ontario, 2016, Repetitive transcranial magnetic stimulation for treatment-resistant depression: a systematic review and meta-analysis of randomized controlled trials, Ont Health Technol Assess Ser, 16, 1

Blumberger, 2012, A randomized double-blind sham-controlled comparison of unilateral and bilateral repetitive transcranial magnetic stimulation for treatment-resistant major depression, World J Biol Psychiatry, 13, 423, 10.3109/15622975.2011.579163

Zhang, 2015, Bilateral repetitive transcranial magnetic stimulation for treatment-resistant depression: a systematic review and meta-analysis of randomized controlled trials, Braz J Med Biol Res, 48, 198, 10.1590/1414-431x20144270

Berlim, 2013, A systematic review and meta-analysis on the efficacy and acceptability of bilateral repetitive transcranial magnetic stimulation (rTMS) for treating major depression, Psychol Med, 43, 2245, 10.1017/S0033291712002802

Stubbeman, 2018, Bilateral neuronavigated 20Hz theta burst TMS for treatment refractory depression: An open label study, Brain Stimul, 11, 953, 10.1016/j.brs.2018.04.012

Rapinesi, 2015, Maintenance deep transcranial magnetic stimulation sessions are associated with reduced depressive relapses in patients with unipolar or bipolar depression, Front Neurol, 6, 10.3389/fneur.2015.00016

Tavares, 2017, Treatment of bipolar depression with deep TMS: results from a double-blind, randomized, parallel group, sham-controlled clinical trial, Neuropsychopharmacology, 42, 2593, 10.1038/npp.2017.26

SH, 2016, Efficacy of repetitive transcranial magnetic stimulation with quetiapine in treating bipolar II depression: a randomized, double-blinded, control study, Sci Rep, 6

Dubin, 2019, A double-blind pilot dosing study of low field magnetic stimulation (LFMS) for treatment-resistant depression (TRD), J Affect Disord, 249, 286, 10.1016/j.jad.2019.02.039

Baeken, 2017, Accelerated rTMS: a potential treatment to alleviate refractory depression, Front Psychol, 2018

Schulze, 2018, Number of pulses or number of sessions? an open-label study of trajectories of improvement for once-vs. twice-daily dorsomedial prefrontal rTMS in major depression, Brain Stimul, 11, 327, 10.1016/j.brs.2017.11.002

Donse, 2018, Simultaneous rTMS and psychotherapy in major depressive disorder: clinical outcomes and predictors from a large naturalistic study, Brain Stimul, 11, 337, 10.1016/j.brs.2017.11.004

Hansen, 2011, Low-Frequency repetitive transcranial magnetic stimulation inferior to electroconvulsive therapy in treating depression, J Ect, 27, 26, 10.1097/YCT.0b013e3181d77645

Berlim, 2013, Efficacy and acceptability of high frequency repetitive transcranial magnetic stimulation (rTMS) versus electroconvulsive therapy (ECT) for major depression: a systematic review and meta-analysis of randomized trials, Depress Anxiety, 30, 614, 10.1002/da.22060

Ren, 2014, Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: a systematic review and meta-analysis, Prog Neuropsychopharmacol Biol Psychiatry, 51, 181, 10.1016/j.pnpbp.2014.02.004

Dunner, 2014, A multisite, naturalistic, observational study of transcranial magnetic stimulation for patients with pharmacoresistant major depressive disorder: durability of benefit over a 1-year follow-up period, J Clin Psychiatry, 75, 1394, 10.4088/JCP.13m08977

Fitzgerald, 2013, An open label trial of clustered maintenance rTMS for patients with refractory depression, Brain Stimul, 6, 292, 10.1016/j.brs.2012.05.003

O'Reardon, 2005, Long-Term maintenance therapy for major depressive disorder with rTMS, J Clin Psychiatry, 66, 1524, 10.4088/JCP.v66n1205

Philip, 2016, Can medication free, treatment-resistant, depressed patients who initially respond to TMS be maintained off medications? A prospective, 12-month multisite randomized pilot study, Brain Stimul, 9, 251, 10.1016/j.brs.2015.11.007

Richieri, 2013, Maintenance transcranial magnetic stimulation reduces depression relapse: a propensity-adjusted analysis, J Affect Disord, 151, 129, 10.1016/j.jad.2013.05.062

Sabesan, 2015, Transcranial magnetic stimulation for geriatric depression: promises and pitfalls, World J Psychiatry, 5, 170, 10.5498/wjp.v5.i2.170

Jorge, 2008, Treatment of vascular depression using repetitive transcranial magnetic stimulation, Arch Gen Psychiatry, 65, 268, 10.1001/archgenpsychiatry.2007.45

Manes, 2001, A controlled study of repetitive transcranial magnetic stimulation as a treatment of depression in the elderly, Int. Psychogeriatr., 13, 225, 10.1017/S1041610201007608

Mosimann, 2004, Repetitive transcranial magnetic stimulation: a putative add-on treatment for major depression in elderly patients, Psychiatry Res, 126, 123, 10.1016/j.psychres.2003.10.006

McConnell, 2001, The transcranial magnetic stimulation motor threshold depends on the distance from coil to underlying cortex: a replication in healthy adults comparing two methods of assessing the distance to cortex, Biol Psychiatry, 49, 454, 10.1016/S0006-3223(00)01039-8

Trevizol, 2019, Unilateral and bilateral repetitive transcranial magnetic stimulation for treatment-resistant late-life depression, Int J Geriatr Psychiatry, 34, 822, 10.1002/gps.5091

Duan, 2018, Mechanisms of transcranial magnetic stimulation treating on post-stroke depression, Front Hum Neurosci, 12, 10.3389/fnhum.2018.00215

Cohen, 2018, Repetitive deep TMS for Parkinson disease: a 3-month double-blind, randomized sham-controlled study, J Clin Neurophysiol, 35, 159, 10.1097/WNP.0000000000000455

Eryılmaz, 2015, Follow-Up study of children whose mothers were treated with transcranial magnetic stimulation during pregnancy: preliminary results, Neuromodulation, 18, 255, 10.1111/ner.12231

Felipe, 2016, Transcranial magnetic stimulation for treatment of major depression during pregnancy: a review, Trends Psychiatry Psychother., 38, 190, 10.1590/2237-6089-2015-0076

Hızlı Sayar, 2014, Transcranial magnetic stimulation during pregnancy, Arch Womens Ment Health, 17, 311, 10.1007/s00737-013-0397-0

Klirova, 2008, Repetitive transcranial magnetic stimulation (rTMS) in major depressive episode during pregnancy, Neuro Endocrinol Lett, 29, 69

Zhang, 2009, Rtms may be a good choice for pregnant women with depression, Arch Womens Ment Health, 12, 189, 10.1007/s00737-009-0058-5

Zhang, 2010, Safety and feasibility of repetitive transcranial magnetic stimulation (rTMS) as a treatment for major depression during pregnancy, Arch Womens Ment Health, 13, 369, 10.1007/s00737-010-0163-5

Garcia, 2010, Repetitive transcranial magnetic stimulation treats postpartum depression, Brain Stimul, 3, 36, 10.1016/j.brs.2009.06.001

Andriotti, 2017, ASSERT trial – How to assess the safety and efficacy of a high frequency rTMS in postpartum depression ? A multicenter, double blinded, randomized, placebo-controlled clinical trial, Contemp Clin Trials Commun, 5, 86, 10.1016/j.conctc.2017.01.004

Kim, 2019, Randomized controlled trial of transcranial magnetic stimulation in pregnant women with major depressive disorder, Brain Stimul, 12, 96, 10.1016/j.brs.2018.09.005

Hameed, 2017, Transcranial magnetic and direct current stimulation in children, Curr Neurol Neurosci Rep, 17, 10.1007/s11910-017-0719-0

Krishnan, 2015, Safety of noninvasive brain stimulation in children and adolescents, Brain Stimul, 8, 76, 10.1016/j.brs.2014.10.012

Wall, 2013, Neurocognitive effects of repetitive transcranial magnetic stimulation in adolescents with major depressive disorder, Front Psychiatry, 4, 10.3389/fpsyt.2013.00165

Leggett, 2015, Repetitive transcranial magnetic stimulation for treatment-resistant depression in adult and youth populations: a systematic literature review and meta-analysis, Prim Care Companion CNS Disord, 17

Iimori, 2019, Effectiveness of the prefrontal repetitive transcranial magnetic stimulation on cognitive profiles in depression, schizophrenia, and Alzheimer's disease: a systematic review, Prog Neuropsychopharmacol Biol Psychiatry, 88, 31, 10.1016/j.pnpbp.2018.06.014

Ilieva, 2018, Age-Related repetitive transcranial magnetic stimulation effects on executive function in depression: a systematic review, Am J Geriatr Psychiatry, 26, 334, 10.1016/j.jagp.2017.09.002

Razza, 2018, A systematic review and meta-analysis on placebo response to repetitive transcranial magnetic stimulation for depression trials, Prog Neuropsychopharmacol Biol Psychiatry, 81, 105, 10.1016/j.pnpbp.2017.10.016

Shen, 2017, Repetitive transcranial magnetic stimulation for the treatment of post-stroke depression: a systematic review and meta-analysis of randomized controlled clinical trials, J Affect Disord, 211, 65, 10.1016/j.jad.2016.12.058

McIntyre, 2016, Repetitive transcranial magnetic stimulation for depression due to cerebrovascular disease: a systematic review, J Stroke Cerebrovasc Dis, 25, 2792, 10.1016/j.jstrokecerebrovasdis.2016.08.043

Nordenskjöld, 2016, Effects of Hesel-coil deep transcranial magnetic stimulation for depression - a systematic review, Nord J Psychiatry, 70, 492, 10.3109/08039488.2016.1166263