Efficacy and tolerability study of ucb L059 in patients with refractory epilepsy

Wülfert, 1989, Facilitation of calcium-dependent cholinergic function by ucb ucb L059, a new “sec-ond generation” nootropic agent, Psychopharmacol Bull, 25, 498 Gower, 1992, ucb L059, a novel anti-convulsant drug: pharmacological profile in animals, Eur J Pharmacol, 222, 193, 10.1016/0014-2999(92)90855-X Löscher, 1993, Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats, Eur J Pharmacol, 232, 147, 10.1016/0014-2999(93)90768-D Gower, 1933, Anticonvulsant effects of ucb L059 in rats: absence of tolerance or discontinuation after chronic administration, Epilepsia, 34, 50 The Commission on Classification, Terminology of the International League Against Epilepsy, 1981, Proposal for the re-vised clinical and electroencephalographic classification of epileptic seizures, Epilepsia, 22, 489, 10.1111/j.1528-1157.1981.tb06159.x The, 1989, Proposal for the re-vised classification of epilepsies and epileptic syndromes, Epilepsia, 30, 389, 10.1111/j.1528-1157.1989.tb05316.x Duncan, 1991, The Chalfont Seizure Severity Scale, J Neurol Neurosurg Psychiatry, 54, 873, 10.1136/jnnp.54.10.873 Chapman, 1984, Evaluation of an-ticonvulsant drugs in DBA/2 mice with sound-induced sei-zures, Arzneimittelforschung Drug Res, 34, 1261 Fisher, 1989, Animal models of the epilepsies, Brain Res Rev, 14, 245, 10.1016/0165-0173(89)90003-9 Swinyard, 1988, Mechanisms of anticon-vulsant drugs, Pharmacology, 2, 95 Verloes, 1988, Effects of nootropic drugs in a scopolamine-induced amnesia model in mice, Psychopharmacology, 95, 226, 10.1007/BF00174514 Chaudhry, 1992, Clinical use of piracetam in epileptic patients, Curr Ther Res Clin Exp, 52, 355, 10.1016/S0011-393X(05)80407-2 Brown, 1993, The effectiveness of piracetam in cortical myoclonus, J Movement Disorders, 8, 63, 10.1002/mds.870080112 Marescaux, 1984, A model of chronic spontaneous petit mal-like seizures in the rat: comparison with pentylenetet-razol-induced seizures, Epilepsia, 25, 326, 10.1111/j.1528-1157.1984.tb04196.x