Efficacy and safety of capecitabine-based first-line chemotherapy in advanced or metastatic breast cancer: a meta-analysis of randomised controlled trials

Oncotarget - Tập 6 Số 36 - Trang 39365-39372 - 2015
Weijiao Yin1, Guangsheng Pei2, Gang Liu1, Li Huang3, Shegan Gao1, Xiaoshan Feng1
1Department of Oncology, the First Affiliated Hospital of Henan University of Science and Technology, Luoyang, PR, China
2Department of Respiratory Medicine, the First Affiliated Hospital of Henan University of Science and Technology, Luoyang, PR, China
3Department of Gynecology, the First Affiliated Hospital of Henan University of Science and Technology, Luoyang, PR, China

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Pegram, 2007, American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer, Arch Pathol Lab Med, 131, 18, 10.5858/2007-131-18-ASOCCO

Jemal, 2012, Global cancer statistics, CA Cancer J Clin, 65, 87

Mamounas, Chemotherapy for isolated locoregional recurrence of breast cancer (CALOR): a randomised trial, Lancet Oncol, 15, 156

El Saghir, ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)dagger, Ann Oncol, 25, 1871

Luck, 2003, Multicenter phase II study of oral capecitabine (Xeloda(“)) in patients with metastatic breast cancer relapsing after treatment with a taxane-containing therapy, Ann Oncol, 14, 1227, 10.1093/annonc/mdg346

Mavroudis, A multicenter randomized phase III trial of vinorelbine/gemcitabine doublet versus capecitabine monotherapy in anthracycline- and taxane-pretreated women with metastatic breast cancer, Ann Oncol, 23, 1164

Harrison, 2009, Phase III study of gemcitabine plus docetaxel compared with capecitabine plus docetaxel for anthracycline-pretreated patients with metastatic breast cancer, J Clin Oncol, 27, 1753, 10.1200/JCO.2007.15.8485

Laws, 2001, Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer, Ann Oncol, 12, 1247, 10.1023/A:1012281104865

Seynaeve, A randomized phase III study comparing pegylated liposomal doxorubicin with capecitabine as first-line chemotherapy in elderly patients with metastatic breast cancer: results of the OMEGA study of the Dutch Breast Cancer Research Group BOOG, Ann Oncol, 25, 599

McQuay, 1996, Assessing the quality of reports of randomized clinical trials: is blinding necessary?, Control Clin Trials, 17, 1, 10.1016/0197-2456(95)00134-4

Stewart, 1998, Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints, Stat Med, 17, 2815, 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8

Eidtmann, Capecitabine plus paclitaxel versus epirubicin plus paclitaxel as first-line treatment for metastatic breast cancer: efficacy and safety results of a randomized, phase III trial by the AGO Breast Cancer Study Group, Breast Cancer Res Treat, 139, 779

Boven, Paclitaxel and bevacizumab with or without capecitabine as first-line treatment for HER2-negative locally recurrent or metastatic breast cancer: a multicentre, open-label, randomised phase 2 trial, Eur J Cancer, 50, 3077

Colucci, A multicenter phase II randomized trial of docetaxel/gemcitabine versus docetaxel/capecitabine as first-line treatment for advanced breast cancer: a Gruppo Oncologico Italia Meridionale study, Oncology, 81, 230

Coates, Capecitabine versus classical cyclophosphamide, methotrexate, and fluorouracil as first-line chemotherapy for advanced breast cancer, J Clin Oncol, 29, 4498

Perol, Final results of ERASME-4: a randomized trial of first-line docetaxel plus either capecitabine or epirubicin for metastatic breast cancer, Oncology, 80, 262

Torres, Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer, J Clin Oncol, 28, 976

Georgoulias, Randomized phase III trial comparing docetaxel plus epirubicin versus docetaxel plus capecitabine as first-line treatment in women with advanced breast cancer, Ann Oncol, 21, 48

Cardoso, Management of locally advanced breast cancer-perspectives and future directions, Nat Rev Clin Oncol, 12, 312

Higashi, 2000, Enhancement of immunohistochemical reactivity for thymidine phosphorylase in breast carcinoma cells after administration of docetaxel as a neoadjuvant chemotherapy in advanced breast cancer patients, Oncol Rep, 7, 945

O'Shaughnessy, Dose-adjusting capecitabine minimizes adverse effects while maintaining efficacy: a retrospective review of capecitabine for metastatic breast cancer, Clin Breast Cancer, 11, 349

Martin, Optimising the dose of capecitabine in metastatic breast cancer: confused, clarified or confirmed?, Ann Oncol, 21, 2145

Traina, Phase II trial of a novel capecitabine dosing schedule in combination with lapatinib for the treatment of patients with HER2-positive metastatic breast cancer, Breast Cancer Res Treat, 131, 111

Traina, Phase 2 trial of a novel capecitabine dosing schedule in combination with bevacizumab for patients with metastatic breast cancer, Cancer, 117, 4125

Shin, Phase II study of 4-weekly capecitabine monotherapy in advanced/metastatic breast cancer, Breast Cancer, 17, 233

Harbeck, Capecitabine monotherapy: review of studies in first-line HER-2-negative metastatic breast cancer, Oncologist, 17, 476

McGuire, 1987, Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene, Science, 235, 177, 10.1126/science.3798106

Duerr, 2009, Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a german breast group 26/breast international group 03-05 study, J Clin Oncol, 27, 1999, 10.1200/JCO.2008.19.6618