Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: A prospective randomized study

Epilepsy and Behavior - Tập 14 - Trang 610-616 - 2009
Patrick Kwan1, Fung Ping Yip1,2, Andrew C.F. Hui1, Howan Leung1, Ping Wing Ng3, Kwok Fai Hui3, Iris H.S. Chan4, Michael H.M. Chan4, Christopher W.K. Lam4
1Division of Neurology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
2Clinical Immunology Unit, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China
3Division of Neurology, Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong, China
4Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China

Tài liệu tham khảo

Isojarvi, 1996, Obesity and endocrine disorders in women taking valproate for epilepsy, Ann Neurol, 39, 579, 10.1002/ana.410390506 Isojarvi, 1998, Valproate, lamotrigine and insulin-mediated risks in women with epilepsy, Ann Neurol, 43, 446, 10.1002/ana.410430406 Pylvanen, 2002, Serum insulin and leptin levels in valproate-associated obesity, Epilepsia, 43, 514, 10.1046/j.1528-1157.2002.31501.x Isojarvi, 1993, Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy, N Engl J Med, 329, 1383, 10.1056/NEJM199311043291904 Isojarvi, 2001, Altered ovarian function and cardiovascular risk factors in valproate treated women, Am J Med, 111, 290, 10.1016/S0002-9343(01)00806-3 Isojarvi, 2005, Effect of antiepileptic drugs on reproductive endocrine function in individuals with epilepsy, CNS Drugs, 19, 207, 10.2165/00023210-200519030-00003 Pylvanen, 2003, Fasting serum insulin and lipid levels in men with epilepsy, Neurology, 60, 571, 10.1212/01.WNL.0000048209.07526.86 Rattya, 2001, Reproductive effects of valproate, carbamazepine, and oxcarbazepine in men with epilepsy, Neurology, 56, 31, 10.1212/WNL.56.1.31 Isojarvi, 1990, Serum hormones in male epileptic patients receiving anticonvulsant medication, Arch Neurol, 47, 670, 10.1001/archneur.1990.00530060082023 Geisler, 1997, Differential effect of carbamazepine and valproate monotherapy on plasma levels of oestrone sulphate and dehydroepiandrosterone sulphate in male epileptic patients, J Endocrinol, 153, 307, 10.1677/joe.0.1530307 Kwan, 2001, Effectiveness of first antiepileptic drug, Epilepsia, 42, 1255, 10.1046/j.1528-1157.2001.04501.x Devinsky, 2000, Stable weight during lamotrigine therapy: a review of 32 studies, Neurology, 54, 973, 10.1212/WNL.54.4.973 Biton, 2001, Weight change associated with valproate and lamotrigine monotherapy in patients with epilepsy, Neurology, 56, 172, 10.1212/WNL.56.2.172 Morrell, 2003, Higher androgens and weight gain with valproate compared with lamotrigine for epilepsy, Epilepsy Res, 54, 189, 10.1016/S0920-1211(03)00085-8 Rattya, 2001, Early hormonal changes during valproate or carbamazepine treatment: a 3-month study, Neurology, 57, 440, 10.1212/WNL.57.3.440 Stephen, 2007, Sodium valproate versus lamotrigine: a randomised comparison of efficacy, tolerability and effects on circulating androgenic hormones in newly diagnosed epilepsy, Epilepsy Res, 75, 122, 10.1016/j.eplepsyres.2007.04.009 Morrell, 2008, Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine, Ann Neurol, 64, 200, 10.1002/ana.21411 Yan, 2005, Clinical features of polycystic ovarian syndrome (PCOS) in China, Fertil Infertil, 84, S167 Stephen, 2001, Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy, Epilepsia, 42, 1002, 10.1046/j.1528-1157.2001.0420081002.x Matthews, 1985, Homeostasis model assessment: insulin resistance and B-cell function from fasting PG and insulin concentrations in man, Diabetologia, 28, 412, 10.1007/BF00280883 Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486–97. Pylvanen, 2006, Insulin-related metabolic changes during treatment with valproate in patients with epilepsy, Epilepsy Behav, 8, 643, 10.1016/j.yebeh.2006.02.008 Ko, 2005, High prevalence of metabolic syndrome in Hong Kong Chinese: comparison of three diagnostic criteria, Diabetes Res Clin Pract, 69, 160, 10.1016/j.diabres.2004.11.015 Pylvanen, 2006, Characterization of insulin secretion in valproate-treated patients with epilepsy, Epilepsia, 47, 1460, 10.1111/j.1528-1167.2006.00546.x Roste, 2005, Antiepileptic drugs alter reproductive endocrine hormones in men with epilepsy, Eur J Neurol, 12, 118, 10.1111/j.1468-1331.2004.00899.x Walker, 2005, FSH and testosterone signaling in Sertoli cells, Reproduction, 130, 15, 10.1530/rep.1.00358 Foresta, 2008, Follicle-stimulating hormone treatment of male infertility, Curr Opin Urol, 18, 602, 10.1097/MOU.0b013e328313647d Usuki, 2000, J Cardiovasc Pharmacol, 36, S421 Guay, 2002, Screening for androgen deficiency in women: methodological and interpretive issues, Fertil Steril, 77, S83, 10.1016/S0015-0282(02)02965-5 Battaglia, 2008, Menstrual cycle-related morphometric and vascular modifications of the clitoris, J Sex Med, 5, 2853, 10.1111/j.1743-6109.2008.00972.x Salonia, 2008, Menstrual cycle-related changes in circulating androgens in healthy women with self-reported normal sexual function, J Sex Med, 5, 854, 10.1111/j.1743-6109.2008.00791.x