Effects of toxin Ts-γ and tityustoxin purified from Tityus serrulatus scorpion venom on isolated rat atria

Y.A. Drumond1, Alicia S. Couto, Tasso Moraes-Santos, Alvair P. Almeida, L. Freire-Maia
1Departamento de Farmacologia, ICB-UFMG, Belo Horizonte, Brazil

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Baer, 1976, Voltage dependent action of tetrodotoxin in mammalian cardiac muscle, Nature, 263, 344, 10.1038/263344a0

Barhanin, 1982, Tityus serrulatus venom contains two classes of toxins, J. biol. Chem., 257, 12,553, 10.1016/S0021-9258(18)33546-4

Barhanin, 1984, Tityus γ toxin, a high affinity effector of the sodium channel in muscle, with a selectivity for channels in the surface membrane, Pflugers Arch., 400, 22, 10.1007/BF00670531

Beneski, 1980, Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin, 77, 639

Cahalan, 1975, Modification of sodium channel gating frog myelinated nerve fibers by Centruroides sculpturatus scorpion venom, J. Physiol., Lond., 244, 511, 10.1113/jphysiol.1975.sp010810

Catterall, 1975, Cooperative activation of potential sodium ionophore by neurotoxins, 72, 1782

Catterall, 1980, Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes, A. Rev. Pharmac. Toxic., 20, 15, 10.1146/annurev.pa.20.040180.000311

Catterall, 1984, The molecular basis of neuronal excitability, Science, 223, 653, 10.1126/science.6320365

Catterall, 1976, Membrane potential-dependent binding of scorpion toxin to the action potential Na+ ionophore, 73, 2682

Couraud, 1982, Two types of scorpion receptor sites, one related to the activation, the other to the inactivation of the action potential sodium channel, Toxicon, 20, 9, 10.1016/0041-0101(82)90138-6

Couto, 1992, Effects of toxin Ts-γ purified from the scorpion Tityus serulatus on isolated rat atria, Toxicon, 30, 339, 10.1016/0041-0101(92)90874-5

Freire-Maia, 1975, Studies on the mechanism of action of tityustoxin (Abstract), Toxicon, 13, 93, 10.1016/0041-0101(75)90029-X

Freire-Maia, 1976, Studies on the mechanism of action of tityustoxin, Vol. 2, 273

Freire-Maia, 1974, Mechanism of the cardiovascular effects produced by purified scorpion toxin in the rat, J. Pharmac. exp. Ther., 188, 207

Gomez, 1966, Separation of toxic components from the Brazilian scorpion—Tityus serrulatus—venom, Mem. Inst. Butantan, 33, 899

Grupp, 1980, Direct myocardial effects of yellow scorpion (Leiurus quinquestriatus) venom on contractile force of isolated guinea-pig atria and papillary muscles, ICRS med. Sci., 8, 666

Koppenhofer, 1968, Incomplete sodium inactivation in nodes of Ranvier treated with scorpion venom, Experientia (Basel), 24, 41, 10.1007/BF02136780

Langer, 1975, Prejunctional effects of a purified toxin from the scorpion Tityus serrulatus, Naunyn-Schmiederbergs Arch. Pharmac., 287, 243, 10.1007/BF00501471

Lazdunski, 1986, Polypeptide toxins as tools to study voltage-sensitive Na+ channels, Ann. N.Y. Acad. Sci., 479, 205, 10.1111/j.1749-6632.1986.tb15571.x

Moss, 1974, On the mechanism of scorpion toxin-induced release of norepinephrine from peripheral adrenergic neurons, J. Pharmac. exp. Ther., 190, 39

Narahashi, 1972, Effects of scorpion venom on squid axon membranes, Am. J. Physiol., 222, 850, 10.1152/ajplegacy.1972.222.4.850

Possani, 1977, Purification and properties of mammalian toxins from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello, Arch. Biochem. Biophys., 180, 394, 10.1016/0003-9861(77)90053-4

Sampaio, 1983, Isolation and characterization of toxic proteins from the venom of the Brazilian scorpion Tityus serrulatus, Toxicon, 21, 265, 10.1016/0041-0101(83)90011-9

Silveira, 1991, Effects of Tityus serrulatus scorpion venom and one of its purified toxins (toxin γ) on the isolated guinea-pig heart, Comp. Biochem. Physiol., 98C, 329

Toledo, 1976, Purification and partial characterization of a second toxin from the scorpion Tityus serrulatus, Comp. Biochem. Physiol., 55B, 249

Vijverberg, 1984, A new scorpion toxin with a very high affinity for sodium channels: an electrophysiological study, J. Physiol., Paris, 79, 275

Warnick, 1976, Electrophysiological observations on the action of purified scorpion venom, tityustoxin, on nerve and skeletal muscle of the rat, J. Pharmac. exp. Ther., 198, 155