Effects of particulate matter on allergic respiratory diseases

Chronic Diseases and Translational Medicine - Tập 4 - Trang 95-102 - 2018
Jin-Zhun Wu1, Dan-Dan Ge2,3, Lin-Fu Zhou4, Ling-Yun Hou3, Ying Zhou3,5, Qi-Yuan Li2,3,5
1Department of Pediatrics, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, China
2Children's Medicine Institute of Medical College, Xiamen University, Xiamen, Fujian 361102, China
3Department of Translational Medicine, Medical College of Xiamen University, Xiamen, Fujian 361102, China
4Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China
5Center for BioMedical Big Data Research, Medical College of Xiamen University, Xiamen, Fujian 361102, China

Tóm tắt

AbstractThe health impact of airborne particulate matter (PM) has long been a concern to clinicians, biologists, and the general public. With many epidemiological studies confirming the association of PM with allergic respiratory diseases, an increasing number of follow‐up empirical studies are being conducted to investigate the mechanisms underlying the toxic effects of PM on asthma and allergic rhinitis. In this review, we have briefly introduced the characteristics of PM and discussed its effects on public health. Subsequently, we have focused on recent studies to elucidate the association between PM and the allergic symptoms of human respiratory diseases. Specifically, we have discussed the mechanism of action of PM in allergic respiratory diseases according to different subtypes: coarse PM (PM2.5‐10), fine PM (PM2.5), and ultrafine PM.

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