Effects of hepatitis B virus X protein on the development of liver cancer
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Szmuness, 1979, Hepatocellular carcinoma and the hepatitis B virus, Prog Med Virol, 24, 40
Beasley, 1981, Hepatocellular carcinoma and hepatitis B virus, Lancet, 2, 1129, 10.1016/S0140-6736(81)90585-7
Robinson, 1994, Molecular events in the pathogenesis of hepadnavirus-associated hepatocellular carcinoma, Annu Rev Med, 45, 297, 10.1146/annurev.med.45.1.297
Feitelson, 1992, Hepatitis B virus infection and primary hepatocellular carcinoma, Clin Micr Rev, 5, 275, 10.1128/CMR.5.3.275
Mason, 1982, Asymmetric replication of duck hepatitis B virus DNA in liver cells, Proc Natl Acad Sci USA, 79, 3997, 10.1073/pnas.79.13.3997
Weiser, 1983, Closed circular viral DNA and asymmetric heterogeneous forms in livers from animals infected with ground squirrel hepatitis virus, J Virol, 48, 1, 10.1128/JVI.48.1.1-9.1983
Colgrove, 1989, Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication, J Virol, 63, 4019, 10.1128/JVI.63.9.4019-4026.1989
Feitelson, 1995, X region delection variants of hepatitis B virus in surface antigen-negative infections and non-A, non-B hepatitis, J Infect Dis, 172, 713, 10.1093/infdis/172.3.713
Kidd-Ljunggren, 1997, Hepatitis B virus X gene 1751 to 1764 mutations, J Gen Virol, 78, 1469, 10.1099/0022-1317-78-6-1469
Nga, 2004, cDNA microarray analysis of early gene expression profiles associated with hepatitis B virus X protein-mediated hepatocarcinogenesis, Bioc Biop Res Comm, 322, 827, 10.1016/j.bbrc.2004.07.188
Hwang, 2003, Detection of the hepatitis B virus X protein (HBx) antigen and anti-HBx antibodies in cases of human hepatocellular carcinoma, J Clin Microbiol, 41, 5598, 10.1128/JCM.41.12.5598-5603.2003
Zhang, 2005, Effects of hepatitis B virus X protein on hTERT expression and activity in hepatoma cells, J Lab Clin Med, 145, 98, 10.1016/j.lab.2004.11.018
Levrero, 1991, Significance of anti-HBx antibodies in hepatitis B virus infection, Hepatology, 13, 143, 10.1002/hep.1840130121
Colgrove, 1989, Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication, J Virol, 63, 4019, 10.1128/JVI.63.9.4019-4026.1989
Spandau, 1988, Trans-activation of viral enhancers by the hepatitis B virus X protein, J Virol, 62, 427, 10.1128/JVI.62.2.427-434.1988
Chen, 1993, The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks, J Virol, 67, 1218, 10.1128/JVI.67.3.1218-1226.1993
Zoulim, 1994, Woodchuck hepatitis virus X protein is required for viral infection in vivo, J Virol, 68, 2026, 10.1128/JVI.68.3.2026-2030.1994
Kim, 1991, HBx gene of hepatitis B virus induces liver cancer in transgenic mice, Nature, 351, 317, 10.1038/351317a0
Ullrich, 1994, Transgenic mouse models of human gastric and hepatic carcinomas, Semin Cancer Biol, 5, 61
Xu, 2002, Enhancement of hepatitis B virus replication by its X protein in transgenic mice, J Virol, 76, 2579, 10.1128/jvi.76.5.2579-2584.2002
Kirkegaard, 1984, Effect of secretin and glucagons on Brunner’s gland secretion in the rat, Gut, 25, 264, 10.1136/gut.25.3.264
Jones, 1995, Epidermal growth factor secreted from the salivary gland is necessary for liver regeneration, Am J Physiol, 268, G872
Shiota, 2000, Occult hepatitis B virus infection in HBs antigen-negative hepatocellular carcinoma in a japanese population, J Med Virol, 62, 151, 10.1002/1096-9071(200010)62:2<151::AID-JMV5>3.0.CO;2-N
Han, 2000, Selective transcriptional regulations in the human liver cell by hepatitis B viral X protein, Bioc Biop Res Comm, 272, 525, 10.1006/bbrc.2000.2801
Gottlob, 1998, The hepatitis B virus HBx protein inhibits caspase 3 activity, J Biol Chem, 273, 33347, 10.1074/jbc.273.50.33347
Chami, 2003, Caspase-dependent alterations of Ca2+ signaling in the induction of apoptosis by hepatitis B virus X protein, J Biol Chem, 278, 31745, 10.1074/jbc.M304202200
Terradillos, 2002, The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver, Oncogene, 21, 377, 10.1038/sj.onc.1205110
Zhang, 2005, Hepatitis B virus X protein up-regulates survivin expression in hepatoma tissues, J Med Virol, 77, 374, 10.1002/jmv.20466
Li, 2003, The inhibition of apoptosis of hepatoma cells induced by HBx is mediated by up-regulation of survivin expression, J Huazhong Univ Sci Technolog Med Sci, 23, 383, 10.1007/BF02829424
Marusawa, 2003, HBXIP functions as a cofactor of survivin in apoptosis suppression, EMBO J, 22, 2729, 10.1093/emboj/cdg263
Chang, 2003, Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway, Int J Oncol, 22, 469
Sheikh, 2000, Role of p53 family members in apoptosis, J Cell Physiol, 182, 171, 10.1002/(SICI)1097-4652(200002)182:2<171::AID-JCP5>3.0.CO;2-3
Qadri, 1996, The hepatitis B virus transactivator protein, HBx, interacts with single-stranded DNA (ss-DNA). Biochemical characterizations of the HBx-ssDNA interactions, J Biol Chem, 271, 15443, 10.1074/jbc.271.26.15443
Haviv, 1996, pX, the HBV-encoded coactivator, interacts with components of the transcription machinery and stimulates transcription in a TAF-independent manner, EMBO J, 15, 3413, 10.1002/j.1460-2075.1996.tb00707.x
Seto, 1990, Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors, Nature, 344, 72, 10.1038/344072a0
Lucito, 1992, Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C, J Virol, 66, 983, 10.1128/JVI.66.2.983-991.1992
Andrisani, 1999, The transcriptional function of the hepatitis B virus X protein and its role in hepatocarcinogenesis, Int J Oncol, 15, 373
Wentz, 2000, Dissociation of DDB1-binding and transactivation properties of the hepatitis B virus X protein, Virus Res, 68, 87, 10.1016/S0168-1702(00)00160-X
Han, 2000, Selective transcriptional regulations in the human liver cell by hepatitis B viral X protein, Biochem Biophys Res Commun, 272, 525, 10.1006/bbrc.2000.2801
Chirillo, 1996, Hepatitis B virus pX activates NF-kappa B-dependent transcription through a Raf-independent pathway, J Virol, 70, 641, 10.1128/JVI.70.1.641-646.1996
Menzo, 1993, Trans-activation of epidermal growth factor receptor gene by the hepatitis B virus X-gene product, Virology, 196, 878, 10.1006/viro.1993.1550
Wang, 1997, Immunohistochemical study of hepatitis C virus core antigen and HBxAg in liver cirrhosis and hepatocellular carcinoma tissues, Chung Hua Chung Liu Tsa Chih, 19, 85
Henkler, 1998, Erk-independent partial activation of AP-1 sites by the hepatitis B virus HBx protein, J Gen Virol, 79, 2737, 10.1099/0022-1317-79-11-2737
Benn, 1995, Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls, Proc Natl Acad Sci USA, 92, 11215, 10.1073/pnas.92.24.11215
Mansour, 1994, Transformation of mammalian cells by constitutively active MAP kinase, Science, 65, 966, 10.1126/science.8052857
Klein, 1999, Src kinases involved in hepatitis B virus replication, EMBO J, 18, 5019, 10.1093/emboj/18.18.5019
Wang, 2004, Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via Induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF- expression, Mole Cell Biol, 24, 10352, 10.1128/MCB.24.23.10352-10365.2004
Yun, 2004, Mitotic aberration coupled with centrosome amplification is induced by hepatitis B virus X oncoprotein via the Ras-mitogen-activated protein/extracellular signal-regulated kinase-mitogen-activated protein pathway, Mole Cancer Res, 2, 159, 10.1158/1541-7786.159.2.3
Choi, 1997, Activating transcription factor 2(ATF2) down-regulates hepatitis B virus X promoter activity by the competition for the activating protein 1 binding site and the formation of the ATF2-Jun heterodimer, J Biol Chem, 272, 16934, 10.1074/jbc.272.27.16934
Tarn, 2002, Hepatitis B virus X protein activates the p38 mitogen-activated protein kinase pathway in dedifferentiated hepatocytes, J Virol, 76, 9763, 10.1128/JVI.76.19.9763-9772.2002
Lee, 2001, The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade, J Biol Chem, 76, 16969, 10.1074/jbc.M011263200
Klein, 1999, Src kinases involved in hepatitis B virus replication, EMBO J, 18, 5019, 10.1093/emboj/18.18.5019
Lee, 1998, HBx protein of hepatitis B virus activates Jak1-STAT signaling, J Biol Chem, 273, 25510, 10.1074/jbc.273.39.25510
Waris, 2001, Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NFκB via oxidative stress, Mol Cell Biol, 21, 7721, 10.1128/MCB.21.22.7721-7730.2001
Ruff-Jamison, 1995, Epidermal growth factor induces the tyrosine phosphorylation and nuclear translocation of Stat 5 in mouse liver, Proc Natl Acad Sci, 92, 4215, 10.1073/pnas.92.10.4215
Cressman, 1995, Rapid activation of the Stat3 transcription complex in liver regeneration, Hepatology, 5, 1443, 10.1002/hep.1840210531
Feitelson, 1993, Hepatitis B X antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma, Oncogene, 8, 1109
Seto, 1990, Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors, Nature, 344, 72, 10.1038/344072a0
Lucito, 1992, Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C, J Virol, 66, 983, 10.1128/JVI.66.2.983-991.1992
Pan, 2001, Hepatitis B virus X protein protects against anti-Fas-mediated apoptosis in human liver cells by inducing NFκB, J Gen Virol, 82, 171, 10.1099/0022-1317-82-1-171
Siddiqui, 1989, Trans-activation of viral enhancers inducing the long terminal repeat of the human immunodeficiency virus by the hepatitis B virus X protein, Virology, 169, 479, 10.1016/0042-6822(89)90177-3
Yun, 2002, NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival, Cancer Lett, 184, 97, 10.1016/S0304-3835(02)00187-8
Wang, 2004, Activating mechanism of transcriptor NF-kappaB regulated by hepatitis B virus X protein in hepatocellular carcinoma, World J Gastroenterol, 10, 356, 10.3748/wjg.v10.i3.356
Birrer, 2003, Hepatocellular carcinoma and hepatitis virus, Ann Clin Lab Sci, 33, 39
Koike, 1994, Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts, J Clin Invest, 94, 44, 10.1172/JCI117343
Shih, 2000, Hepatitis B virus X protein inhibits transforming growth factor-induced apoptosis through the activation of phosphatidylinositol 3-kinase pathway, J Biol Chem, 275, 25858, 10.1074/jbc.M003578200
Kim, 1994, Specific association of human telomerase activity with immortal cells and cancer, Science, 266, 2011, 10.1126/science.7605428
Poole, 2001, Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT), Gene, 269, 1, 10.1016/S0378-1119(01)00440-1
Horikawa, 2001, Cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome, J Natl Cancer Inst, 93, 1171, 10.1093/jnci/93.15.1171
Ferber, 2003, Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers, Oncogene, 22, 3813, 10.1038/sj.onc.1206528
Dubiel, 1992, Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family, J Biol Chem, 267, 22699, 10.1016/S0021-9258(18)50002-8
Shiyanov, 1999, The naturally occurring mutants of DDB are impaired in stimulating nuclear import of the p125 subunit and E2F1-activated transcription, Mol Cell Biol, 19, 4935, 10.1128/MCB.19.7.4935
Abramic, 1991, Purification of an ultraviolet-inducible, damage-specific DNA-binding protein from primate cells, J Biol Chem, 266, 22493, 10.1016/S0021-9258(18)54599-3
Lin, 2000, The paramyxovirus simian virus 5 V protein slows progression of the cell cycle, J Virol, 74, 9152, 10.1128/JVI.74.19.9152-9166.2000
Bergametti, 2002, Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex, J Virol, 76, 6495, 10.1128/JVI.76.13.6495-6501.2002
Benn, 1994, Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade, Proc Natl Acad Sci USA, 91, 10350, 10.1073/pnas.91.22.10350
Lin, 1998, The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein, Virology, 249, 189, 10.1006/viro.1998.9317
Qadri, 1995, Hepatitis B virus transactivator protein X interacts with the TATA-Binding protein, Proc Natl Acad Sci USA, 92, 1003, 10.1073/pnas.92.4.1003
Elmore, 1997, Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis, Proc Natl Acad Sci USA, 94, 14707, 10.1073/pnas.94.26.14707
Williams, 1995, The hepatitis B virus X protein targets the basic region-leucine zipper domain of CREB, Proc Natl Acad Sci USA, 92, 3819, 10.1073/pnas.92.9.3819
Barnabas, 1997, The hepatitis B virus X protein enhances the DNA binding potential and transcription efficacy of bZip transcription factors, J Biol Chem, 272, 20684, 10.1074/jbc.272.33.20684
Ohno, 1999, Human hepatitis B virus X protein augments the DNAbinding of nuclear factor for IL-6 through its basicleucine zipper domain, J Med Virol, 58, 11, 10.1002/(SICI)1096-9071(199905)58:1<11::AID-JMV2>3.0.CO;2-H
Qadri, 1996, Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH, Proc Natl Acad Sci, 93, 10578, 10.1073/pnas.93.20.10578
Lin, 1997, Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5, J Biol Chem, 272, 7132, 10.1074/jbc.272.11.7132
Rahmani, 2000, Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential, J Virol, 74, 2840, 10.1128/JVI.74.6.2840-2846.2000
Zhang, 2000, Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex, J Biol Chem, 275, 15157, 10.1074/jbc.M910378199
Tanaka, 2004, Interaction of the hepatitis B virus X protein (HBx) with heat shock protein 60 enhances HBx-mediated apoptosis, Biochem Biophys Res Commun, 318, 461, 10.1016/j.bbrc.2004.04.046
Zhang, 2005, HBx protein of hepatitis B virus (HBV) can form complex with mitochondrial HSP60 and HSP70, Arch Virol, 150, 1579, 10.1007/s00705-005-0521-1
Su, 1996, Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins, J Virol, 70, 4558, 10.1128/JVI.70.7.4558-4566.1996
Dorjsuren, 1998, RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X protein, Mol Cell Biol, 18, 7546, 10.1128/MCB.18.12.7546
Kong, 2000, Direct binding of hepatitis B virus X protein and retinoid X receptor contributes to phosphoenolpyruvate carboxykinase gene transactivation, FEBS Lett, 483, 114, 10.1016/S0014-5793(00)02091-3
Chen, 2000, Expression of integrated hepatitis B virus X variants in human hepatocellular carcinomas and its significance, Biochem Biophys Res Commun, 276, 885, 10.1006/bbrc.2000.3562
Diao, 2001, X protein of hepatitis B virus inhibits Fas-mediated apoptosis and is associated with up-regulation of the SAPK/JNK pathway, J Biol Chem, 276, 8328, 10.1074/jbc.M006026200
Melegari, 1998, Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication, J Virol, 72, 1737, 10.1128/JVI.72.3.1737-1743.1998
Stohwasser, 2003, Hepatitis B virus HBx peptide 116-138 and proteasome activator PA28 compete for binding to the proteasome alpha4/MC6 subunit, Biol Chem, 384, 39, 10.1515/BC.2003.005
Kwee, 1992, Alternate translation initiation on hepatitis B virus X mRNA produces multiple polypeptides that differentially transactivate class II and III promoters, J Virol, 66, 4382, 10.1128/JVI.66.7.4382-4389.1992
Chol, 1996, A positive regulatory sequence of hepatitis B viral small X promoter, Eur J Biochem, 239, 579, 10.1111/j.1432-1033.1996.0579u.x
Andrisani, 1999, The transcriptional function of the hepatitis B virus X protein and its role in hepatocarcinogenesis (Review), Int J Oncol, 15, 373
Jaitovich-Groisman, 2001, Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue, J Biol Chem, 276, 14124, 10.1074/jbc.M010852200
Shirakata, 2003, Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential, J Biol Chem, 278, 22071, 10.1074/jbc.M301606200
Fields, 1989, A novel genetic system to detect protein-protein interactions, Nature, 340, 245, 10.1038/340245a0
Gyuris, 1993, Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2, Cell, 75, 791, 10.1016/0092-8674(93)90498-F
Dubiel, 1995, Subunits of the regulatory complex of the 26S protease, Mol Biol Rep, 21, 27, 10.1007/BF00990967
Coux, 1996, Structure and functions of the 20S and 26S proteasomes, Annu Rev Biochem, 65, 801, 10.1146/annurev.bi.65.070196.004101