Effects of genistein supplementation on genome-wide DNA methylation and gene expression in patients with localized prostate cancer
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2016, Prostate Cancer Facts and Figures 2016
Sartor, 2011, Progression of metastatic castrate-resistant prostate cancer: Impact of therapeutic intervention in the post-docetaxel space, J Hematol Oncol, 4, 18, 10.1186/1756-8722-4-18
Skolarus, 2014, American Cancer Society prostate cancer survivorship care guidelines, CA Cancer J Clin, 64, 225, 10.3322/caac.21234
Hieronymus, 2014, Copy number alteration burden predicts prostate cancer relapse, Proc Natl Acad Sci USA, 111, 11139, 10.1073/pnas.1411446111
Ferlay, 2001, Globocan 2000: Cancer Incidence, Mortality and Prevalence Worldwide
Kimura, 2012, East meets West: Ethnic differences in prostate cancer epidemiology between East Asians and Caucasians, Chin J Cancer, 31, 421, 10.5732/cjc.011.10324
Reinli, 1996, Phytoestrogen content of foods–a compendium of literature values, Nutr Cancer, 26, 123, 10.1080/01635589609514470
Adlercreutz, 1993, Plasma concentrations of phyto-oestrogens in Japanese men, Lancet, 342, 1209, 10.1016/0140-6736(93)92188-Y
Morton, 1997, Lignans and isoflavonoids in plasma and prostatic fluid in men: Samples from Portugal, Hong Kong, and the United Kingdom, Prostate, 32, 122, 10.1002/(SICI)1097-0045(19970701)32:2<122::AID-PROS7>3.0.CO;2-O
Hwang, 2009, Soy food consumption and risk of prostate cancer: A meta-analysis of observational studies, Nutr Cancer, 61, 598, 10.1080/01635580902825639
Van Poppel, 2011, Chemoprevention of prostate cancer with nutrients and supplements, Cancer Manag Res, 3, 91, 10.2147/CMAR.S18503
Barnes, 1995, Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer, J Cell Biochem (Suppl), S22, 181, 10.1002/jcb.240590823
Takimoto, 2003, Phase I pharmacokinetic and pharmacodynamic analysis of unconjugated soy isoflavones administered to individuals with cancer, Cancer Epidemiol Biomarkers Prev, 12, 1213
Gardner, 2009, Prostatic soy isoflavone concentrations exceed serum levels after dietary supplementation, Prostate, 69, 719, 10.1002/pros.20922
Bloedon, 2002, Safety and pharmacokinetics of purified soy isoflavones: Single-dose administration to postmenopausal women, Am J Clin Nutr, 76, 1126, 10.1093/ajcn/76.5.1126
YildizFPhytoestrogens in functional foodsCRC PressBoca Raton, FL2005https://doi.org/10.1201/978142002759410.1201/9781420027594
Morito, 2001, Interaction of phytoestrogens with estrogen receptors alpha and beta, Biol Pharm Bull, 24, 351, 10.1248/bpb.24.351
Chang, 1999, Estrogen receptor-beta: Implications for the prostate gland, Prostate, 40, 115, 10.1002/(SICI)1097-0045(19990701)40:2<115::AID-PROS7>3.0.CO;2-3
Kumar, 2011, Synergistic chemoprotective mechanisms of dietary phytoestrogens in a select combination against prostate cancer, J Nutr Biochem, 22, 723, 10.1016/j.jnutbio.2010.06.003
Wang, 2007, Genistein chemoprevention of prostate cancer in TRAMP mice, J Carcinog, 6, 3, 10.1186/1477-3163-6-3
Davis, 2002, Expression of prostate-specific antigen is transcriptionally regulated by genistein in prostate cancer cells, Mol Carcinog, 34, 91, 10.1002/mc.10053
Bektic, 2004, Androgen receptor regulation by physiological concentrations of the isoflavonoid genistein in androgen-dependent LNCaP cells is mediated by estrogen receptor beta, Eur Urol, 45, 245, 10.1016/j.eururo.2003.09.001
Shen, 2000, Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells, Mol Carcinog, 29, 92, 10.1002/1098-2744(200010)29:2<92::AID-MC6>3.0.CO;2-Q
Davis, 1998, Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells, Nutr Cancer, 32, 123, 10.1080/01635589809514730
Raffoul, 2006, Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest, BMC Cancer, 6, 107, 10.1186/1471-2407-6-107
Li, 2002, Down-regulation of invasion and angiogenesis-related genes identified by cDNA microarray analysis of PC3 prostate cancer cells treated with genistein, Cancer Lett, 186, 157, 10.1016/S0304-3835(02)00349-X
Guo, 2007, Suppression of VEGF-mediated autocrine and paracrine interactions between prostate cancer cells and vascular endothelial cells by soy isoflavones, J Nutr Biochem, 18, 408, 10.1016/j.jnutbio.2006.08.006
Li, 2004, Regulation of gene expression and inhibition of experimental prostate cancer bone metastasis by dietary genistein, Neoplasia, 6, 354, 10.1593/neo.03478
Zhang, 2008, A novel anti-cancer effect of genistein: Reversal of epithelial mesenchymal transition in prostate cancer cells, Acta Pharmacol Sin, 29, 1060, 10.1111/j.1745-7254.2008.00831.x
Kumi-Diaka, 2006, Influence of genistein isoflavone on matrix metalloproteinase-2 expression in prostate cancer cells, J Med Food, 9, 491, 10.1089/jmf.2006.9.491
Kazi, 2003, Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein, Biochem Pharmacol, 66, 965, 10.1016/S0006-2952(03)00414-3
Kumi-Diaka, 2000, The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP, Biol Cell, 92, 595, 10.1016/S0248-4900(00)01109-6
Lee, 2012, Inhibition of IGF-1 signaling by genistein: Modulation of E-cadherin expression and downregulation of β-catenin signaling in hormone refractory PC-3 prostate cancer cells, Nutr Cancer, 64, 153, 10.1080/01635581.2012.630161
Xu, 2006, Genistein inhibits matrix metalloproteinase type 2 activation and prostate cancer cell invasion by blocking the transforming growth factor beta-mediated activation of mitogen-activated protein kinase-activated protein kinase 2-27-kDa heat shock protein pathway, Mol Pharmacol, 70, 869, 10.1124/mol.106.023861
Davis, 1999, Genistein inhibits NF-kappaB activation in prostate cancer cells, Nutr Cancer, 35, 167, 10.1207/S15327914NC352_11
Li, 2002, Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway, Clin Cancer Res, 8, 2369
Akiyama, 1987, Genistein, a specific inhibitor of tyrosine-specific protein kinases, J Biol Chem, 262, 5592, 10.1016/S0021-9258(18)45614-1
Park, 2010, The antioxidant effects of genistein are associated with AMP-activated protein kinase activation and PTEN induction in prostate cancer cells, J Med Food, 13, 815, 10.1089/jmf.2009.1359
Raschke, 2006, Genistein protects prostate cells against hydrogen peroxide-induced DNA damage and induces expression of genes involved in the defence against oxidative stress, Carcinogenesis, 27, 2322, 10.1093/carcin/bgl082
Swami, 2009, Inhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients, Int J Cancer, 124, 2050, 10.1002/ijc.24161
Adjakly, 2011, DNA methylation and soy phytoestrogens: Quantitative study in DU-145 and PC-3 human prostate cancer cell lines, Epigenomics, 3, 795, 10.2217/epi.11.103
Vardi, 2010, Soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2 and BRCA1 promoter in prostate cancer cells, In Vivo, 24, 393
Fang, 2005, Reversal of hypermethylation and reactivation of 16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy, Clin Cancer Res, 11, 7033, 10.1158/1078-0432.CCR-05-0406
Majid, 2010, Genistein reverses hyper-methylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer, Cancer, 116, 66, 10.1002/cncr.24662
Kikuno, 2008, Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells, Int J Cancer, 123, 552, 10.1002/ijc.23590
Li, 2012, Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion, Epigenetics, 7, 940, 10.4161/epi.21236
Rabiau, 2011, miRNAs differentially expressed in prostate cancer cell lines after soy treatment, In Vivo, 25, 917
Chen, 2011, MicroRNAs 221/222 and genistein-mediated regulation of ARHI tumor suppressor gene in prostate cancer, Cancer Prev Res (Phila), 4, 76, 10.1158/1940-6207.CAPR-10-0167
Chiyomaru, 2013, Genistein up-regulates tumor suppressor microRNA-574-3p in prostate cancer, PLoS One, 8, e58929, 10.1371/journal.pone.0058929
Hillman, 2001, Genistein potentiates the radiation effect on prostate carcinoma cells, Clin Cancer Res, 7, 382
Li, 2006, Antitumor and antimetastatic activities of docetaxel are enhanced by genistein through regulation of osteoprotegerin/receptor activator of nuclear factor-kappaB (RANK)/RANK ligand/MMP-9 signaling in prostate cancer, Cancer Res, 66, 4816, 10.1158/0008-5472.CAN-05-3752
Spagnuolo, 2015, Genistein and cancer: Current status, challenges, and future directions, Adv Nutr, 6, 408, 10.3945/an.114.008052
Katoh, 2011, Network of WNT and other regulatory signaling cascades in pluripotent stem cells and cancer stem cells, Curr Pharm Biotechnol, 12, 160, 10.2174/138920111794295710
Mori, 2008, Both beta-actin and GAPDH are useful reference genes for normalization of quantitative RT-PCR in human FFPE tissue samples of prostate cancer, Prostate, 68, 1555, 10.1002/pros.20815
Eisen, 1998, Cluster analysis and display of genome-wide expression patterns, Proc Natl Acad Sci USA, 95, 14863, 10.1073/pnas.95.25.14863
Saldanha, 2004, Java Treeview - extensible visualization of micro-array data, Bioinformatics, 20, 3246, 10.1093/bioinformatics/bth349
Barfield, 2012, CpGassoc: An R function for analysis of DNA methylation microarray data, Bioinformatics, 28, 1280, 10.1093/bioinformatics/bts124
http://www.qiagen.com/ingenuityQiagen's Ingenuity Pathway Analysis
Dennis, 2003, DAVID: Database for Annotation, Visualization, and Integrated Discovery, Genome Biol, 4, 3, 10.1186/gb-2003-4-5-p3
Wang, 2010, Genistein increases gene expression by demethylation of WNT5a promoter in colon cancer cell line SW1116, Anticancer Res, 30, 4537
Gao, 1991, Cloning and expression of a widely distributed (type IV) adenylyl cyclase, Proc Natl Acad Sci USA, 88, 10178, 10.1073/pnas.88.22.10178
Brikun, 2014, A panel of DNA methylation markers reveals extensive methylation in histologically benign prostate biopsy cores from cancer patients, Biomark Res, 2, 25, 10.1186/s40364-014-0025-9
Monti, 2010, Sialidases in vertebrates: A family of enzymes tailored for several cell functions, Adv Carbohydr Chem Biochem, 64, 403, 10.1016/S0065-2318(10)64007-3
Uemura, 2009, Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4, Oncogene, 28, 1218, 10.1038/onc.2008.471
Kato, 2001, Overexpressing of lysosomal-type sialidase leads to suppression of metastasis associated with reversion of malignant phenotype in murine B16 melanoma cells, Int J Cancer, 92, 797, 10.1002/ijc.1268
Chang, 2016, MicroRNA-125b promotes invasion and metastasis of gastric cancer by targeting STARD13 and NEU1, Tumour Biol, 37, 12141, 10.1007/s13277-016-5094-y
Haxho, 2016, Neuraminidase-1: A novel therapeutic target in multistage tumorigenesis, Oncotarget, 7, 40860, 10.18632/oncotarget.8396
Liu, 2014, Notch3 is important for TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer bone metastasis by regulating ZEB-1, Cancer Gene Ther, 21, 364, 10.1038/cgt.2014.39
Danza, 2013, Notch3 is activated by chronic hypoxia and contributes to the progression of human prostate cancer, Int J Cancer, 133, 2577
Terada, 2014, Correlation of Sprouty1 and Jagged1 with aggressive prostate cancer cells with different sensitivities to androgen deprivation, J Cell Biochem, 115, 1505, 10.1002/jcb.24805
Pedrosa, 2016, Notch signaling dynamics in the adult healthy prostate and in prostatic tumor development, Prostate, 76, 80, 10.1002/pros.23102
Pedrosa, 2015, Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions, Oncotarget, 6, 24404, 10.18632/oncotarget.4380
Danza, 2012, Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells, Mol Cancer Res, 10, 230, 10.1158/1541-7786.MCR-11-0296
Rampias, 2014, A new tumor suppressor role for the Notch pathway in bladder cancer, Nat Med, 20, 1199, 10.1038/nm.3678
Hernandez Tejada, 2014, The challenge of targeting notch in hematologic malignancies, Front Pediatr, 2, 54, 10.3389/fped.2014.00054
Giachino, 2015, A tumor suppressor function for Notch signaling in forebrain tumor subtypes, Cancer Cell, 28, 730, 10.1016/j.ccell.2015.10.008
Jaskula-Sztul, 2015, Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction, Mol Cancer Ther, 14, 499, 10.1158/1535-7163.MCT-14-0073
Sriuranpong, 2001, Notch signaling induces cell cycle arrest in small cell lung cancer cells, Cancer Res, 61, 3200
Liu, 2013, Genistein induces G2/M arrest in gastric cancer cells by increasing the tumor suppressor PTEN expression, Nutr Cancer, 65, 1034, 10.1080/01635581.2013.810290
Su, 2005, The novel targets for anti-angiogenesis of genistein on human cancer cells, Biochem Pharmacol, 69, 307, 10.1016/j.bcp.2004.09.025
Jagadeesh, 2006, Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells, Cancer Res, 66, 2107, 10.1158/0008-5472.CAN-05-2494
Mahmoud, 2015, Genistein increases estrogen receptor beta expression in prostate cancer via reducing its promoter methylation, J Steroid Biochem Mol Biol, 152, 62, 10.1016/j.jsbmb.2015.04.018
Whirledge, 2015, Genistein disrupts glucocorticoid receptor signaling in human uterine endometrial Ishikawa cells, Environ Health Perspect, 123, 80, 10.1289/ehp.1408437
Bhamre, 2010, Gene expression changes induced by genistein in the prostate cancer cell line LNCaP, Open Prostate Cancer J, 3, 86, 10.2174/1876822901003010086
Ghaemi, 2012, Genistein induces a protective immunomodulatory effect in a mouse model of cervical cancer, Iran J Immunol, 9, 119
Korde, 2009, Childhood soy intake and breast cancer risk in Asian American women, Cancer Epidemiol Biomarkers Prev, 18, 1050, 10.1158/1055-9965.EPI-08-0405