Effects of everolimus on macrophage-derived foam cell behavior

Cardiovascular Revascularization Medicine - Tập 15 Số 5 - Trang 269-277 - 2014
Steven Hsu1, Eugen Koren1, Yen Chan1, Mirna Koscec1, Alexander Sheehy1, Frank D. Kolodgie2, Renu Virmani2, D Feder1
1Abbott Vascular, 3200 Lakeside Drive, Santa Clara, CA 95054, USA
2CVPath Institute, Inc., 19 Firstfield Road, Gaithersburg, MD, 20878, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Ross, 1999, Atherosclerosis–an inflammatory disease, N Engl J Med, 340, 115, 10.1056/NEJM199901143400207

Hansson, 2005, Inflammation, atherosclerosis, and coronary artery disease, N Engl J Med, 352, 1685, 10.1056/NEJMra043430

Hansson, 2006, Inflammation and atherosclerosis, Annu Rev Pathol, 1, 297, 10.1146/annurev.pathol.1.110304.100100

Schuler, 1997, Sdz rad, a new rapamycin derivative: pharmacological properties in vitro and in vivo, Transplantation, 64, 36, 10.1097/00007890-199707150-00008

Carrera, 2004, Tor signaling in mammals, J Cell Sci, 117, 4615, 10.1242/jcs.01311

O'Reilly, 2010, Biomarker development for the clinical activity of the mtor inhibitor everolimus (rad001): processes, limitations, and further proposals, Transl Oncol, 3, 65, 10.1593/tlo.09277

Lavigne, 2012, Antirestenotic mechanisms of everolimus on human coronary artery smooth muscle cells: inhibition of human coronary artery smooth muscle cell proliferation, but not migration, J Cardiovasc Pharmacol, 59, 165, 10.1097/FJC.0b013e31823a39c7

Tsuchiya, 2006, Effect of everolimus-eluting stents in different vessel sizes (from the pooled future i and ii trials), Am J Cardiol, 98, 464, 10.1016/j.amjcard.2006.02.054

Garg, 2010, Coronary stents: current status, J Am Coll Cardiol, 56, S1, 10.1016/j.jacc.2010.06.007

Gomez-Lara, 2011, Head-to-head comparison of the neointimal response between metallic and bioresorbable everolimus-eluting scaffolds using optical coherence tomography, JACC Cardiovasc Interv, 4, 1271, 10.1016/j.jcin.2011.08.016

Cole, 1998, Effect of sdz rad on transplant arteriosclerosis in the rat aortic model, Transplant Proc, 30, 2200, 10.1016/S0041-1345(98)00590-9

Farb, 2002, Oral everolimus inhibits in-stent neointimal growth, Circulation, 106, 2379, 10.1161/01.CIR.0000033973.06059.04

Matsumoto, 2003, Differential effect of cyclosporine a and sdz rad on neointima formation of carotid allografts in apolipoprotein e-deficient mice, Transplantation, 76, 1166, 10.1097/01.TP.0000090393.75600.32

Mueller, 2008, Prevention of atherosclerosis by the mtor inhibitor everolimus in ldlr-/- mice despite severe hypercholesterolemia, Atherosclerosis, 198, 39, 10.1016/j.atherosclerosis.2007.09.019

Verheye, 2007, Selective clearance of macrophages in atherosclerotic plaques by autophagy, J Am Coll Cardiol, 49, 706, 10.1016/j.jacc.2006.09.047

Martinet, 2007, Everolimus-induced mtor inhibition selectively depletes macrophages in atherosclerotic plaques by autophagy, Autophagy, 3, 241, 10.4161/auto.3711

Martinet, 2007, Selective depletion of macrophages in atherosclerotic plaques via macrophage-specific initiation of cell death, Trends Cardiovasc Med, 17, 69, 10.1016/j.tcm.2006.12.004

Baetta, 2009, Everolimus inhibits monocyte/macrophage migration in vitro and their accumulation in carotid lesions of cholesterol-fed rabbits, J Pharmacol Exp Ther, 328, 419, 10.1124/jpet.108.144147

Seifert, 2011, Everolimus-eluting stents inhibit neointimal macrophage foam cell accumulations in the coronary arteries of familial hypercholesterolemic swine

Zhao, 2012, Inhibition of experimental neointimal hyperplasia and neoatherosclerosis by local, stent-mediated delivery of everolimus, J Vasc Surg, 56, 1680, 10.1016/j.jvs.2012.04.022

Warrior, 2000, Application of quantigene nucleic acid quantification technology for high throughput screening, J Biomol Screen, 5, 343, 10.1177/108705710000500506

Canales, 2006, Evaluation of DNA microarray results with quantitative gene expression platforms, Nat Biotechnol, 24, 1115, 10.1038/nbt1236

Nakazawa, 2011, Evaluation of polymer-based comparator drug-eluting stents using a rabbit model of iliac artery atherosclerosis, Circ Cardiovasc Interv, 4, 38, 10.1161/CIRCINTERVENTIONS.110.957654

Yazdani, 2013, Preclinical evaluation of second-generation everolimus- and zotarolimus-eluting coronary stents, J Invasive Cardiol, 25, 383

Hayden, 2002, Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol, J Lipid Res, 43, 26, 10.1016/S0022-2275(20)30183-8

Wang, 1999, Induced expression of adipophilin mrna in human macrophages stimulated with oxidized low-density lipoprotein and in atherosclerotic lesions, FEBS Lett, 462, 145, 10.1016/S0014-5793(99)01521-5

Wang, 2011, Receptor mediated elevation in fabp4 levels by advanced glycation end products induces cholesterol and triacylglycerol accumulation in thp-1 macrophages, Lipids, 46, 479, 10.1007/s11745-011-3542-4

Blanc-Brude, 2007, Iap survivin regulates atherosclerotic macrophage survival, Arterioscler Thromb Vasc Biol, 27, 901, 10.1161/01.ATV.0000258794.57872.3f

Pearse, 1992, Differential expression of clusterin in inducible models of apoptosis, Int Immunol, 4, 1225, 10.1093/intimm/4.11.1225

Debure, 2003, Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alteration, J Cell Sci, 116, 3109, 10.1242/jcs.00619

Perkins, 2009, Xience vtm everolimus-eluting coronary stent system: a preclinical assessment, J Interv Cardiol, 22, S28, 10.1111/j.1540-8183.2009.00451.x

Galis, 1994, Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques, J Clin Invest, 94, 2493, 10.1172/JCI117619

Newby, 2009, Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes, Thromb Haemost, 101, 1006, 10.1160/TH08-07-0469

Bjornheden, 1987, Oxygen consumption in aortic tissue from rabbits with diet-induced atherosclerosis, Arteriosclerosis, 7, 238, 10.1161/01.ATV.7.3.238

Clarke, 2006, Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis, Nat Med, 12, 1075, 10.1038/nm1459

Tabas, 2005, Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency, Arterioscler Thromb Vasc Biol, 25, 2255, 10.1161/01.ATV.0000184783.04864.9f

Jones, 2003, Matrix metalloproteinases: a review of their structure and role in acute coronary syndrome, Cardiovasc Res, 59, 812, 10.1016/S0008-6363(03)00516-9

Maiuri, 2007, Self-eating and self-killing: crosstalk between autophagy and apoptosis, Nat Rev Mol Cell Biol, 8, 741, 10.1038/nrm2239

Inbal, 2002, Dap kinase and drp-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death, J Cell Biol, 157, 455, 10.1083/jcb.200109094

Martinet, 2002, Gene expression profiling of apoptosis-related genes in human atherosclerosis: upregulation of death-associated protein kinase, Arterioscler Thromb Vasc Biol, 22, 2023, 10.1161/01.ATV.0000041843.44312.12

Li, 2006, Cholesterol-induced apoptotic macrophages elicit an inflammatory response in phagocytes, which is partially attenuated by the mer receptor, J Biol Chem, 281, 6707, 10.1074/jbc.M510579200

Ait-Oufella, 2008, Defective mer receptor tyrosine kinase signaling in bone marrow cells promotes apoptotic cell accumulation and accelerates atherosclerosis, Arterioscler Thromb Vasc Biol, 28, 1429, 10.1161/ATVBAHA.108.169078

Thorp, 2008, Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-/- mice, Arterioscler Thromb Vasc Biol, 28, 1421, 10.1161/ATVBAHA.108.167197

Serruys, 2009, A bioabsorbable everolimus-eluting coronary stent system (absorb): 2-year outcomes and results from multiple imaging methods, Lancet, 373, 897, 10.1016/S0140-6736(09)60325-1

Kang, 2013, Comparison of edge vascular response after sirolimus- and paclitaxel-eluting stent implantation, Int J Cardiol, 165, 46, 10.1016/j.ijcard.2011.07.108

Shao-liang, 2009, Different edge effects of paclitaxel- and sirolimus-eluting stents on proximal and distal edges in patients with unstable angina: serial intravascular ultrasound analysis, Chin Med J, 122, 1603

Fagglotto, 1984, Studies of hypercholesterolemia in the nonhuman primate, i. Changes that lead to fatty streak formation, Arteriosclerosis, 4, 323, 10.1161/01.ATV.4.4.323

Schaffner, 1980, Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages, Am J Pathol, 100, 57

Gerrity, 1981, The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions, Am J Pathol, 103, 181

Skrinska, 1988, Suppression of foam cell lesions in hypercholesterolemic rabbits by inhibition of thromboxane a2 synthesis, Arteriosclerosis, 8, 359, 10.1161/01.ATV.8.4.359

Klurfeld, 1985, Identification of foam cells in human atherosclerotic lesions as macrophages using monoclonal antibodies, Arch Pathol Lab Med, 109, 445

Koniari, 2011, Structural and biomechanical alterations in rabbit thoracic aortas are associated with the progression of atherosclerosis, Lipids Health Dis, 10, 125, 10.1186/1476-511X-10-125

Thomas, 2007, Genomics of foam cells and nonfoamy macrophages from rabbits identifies arginase-i as a differential regulator of nitric oxide production, Arterioscler Thromb Vasc Biol, 27, 571, 10.1161/01.ATV.0000256470.23842.94

Wang, 2010, Pharmacokinetic sub-study in the spirit iii randomized and controlled trial of xience v everolimus eluting coronary stent system, J Interv Cardiol, 23, 26, 10.1111/j.1540-8183.2009.00517.x