Effects of chronic Δ 9 -tetrahydrocannabinol treatment on Rho/Rho-kinase signalization pathway in mouse brain

Saudi Pharmaceutical Journal - Tập 25 - Trang 1078-1081 - 2017
Halil Mahir Kaplan1, Percin Pazarci2
1Department of Pharmacology, Faculty of Medicine, Cukurova University, 01330 Adana, Turkey
2Department of Medical Biology, Faculty of Medicine, Cukurova University, 01330 Adana, Turkey

Tài liệu tham khảo

Ahnert-Hilger, 2004, Differential effects of Rho GTPases on axonal and dendritic development in hippocampal neurones, J. Neurochem., 90, 9, 10.1111/j.1471-4159.2004.02475.x Ayman, 2003, Receptor-independent activation of Rho-kinase-mediated calcium sensitisation in smooth muscle, Br. J. Pharmacol., 139, 1532, 10.1038/sj.bjp.0705394 Cao, 2014, The potential therapeutic effects of THC on Alzheimer's disease, J. Alzheimer's Disease: JAD, 42, 973, 10.3233/JAD-140093 Charest, 2007, Big roles for small GTPases in the control of directed cell movement, Biochem. J., 401, 377, 10.1042/BJ20061432 Chen, 2007, RhoA regulates dendrite branching in hippocampal neurons by decreasing cypin protein levels, J. Neurosci.: Off. J. Soc. Neurosci., 27, 8378, 10.1523/JNEUROSCI.0872-07.2007 Franklin, 2013, Cannabinoid receptor agonists upregulate and enhance serotonin 2A (5-HT(2A)) receptor activity via ERK1/2 signaling, Synapse, 67, 145, 10.1002/syn.21626 Galve-Roperh, 2006, Endocannabinoids: a new family of lipid mediators involved in the regulation of neural cell development, Curr. Pharm. Des., 12, 2319, 10.2174/138161206777585139 Hall, 1998, Rho GTPases and the actin cytoskeleton, Science, 279, 509, 10.1126/science.279.5350.509 Hirvonen, 2012, Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers, Mol. Psychiatry, 17, 642, 10.1038/mp.2011.82 Julian, 2014, Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions, Small GTPases, 5, e29846, 10.4161/sgtp.29846 Kurihara, 2006, Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils, J. Biol. Chem., 281, 12908, 10.1074/jbc.M510871200 Li, 2015, Activation of dopamine D1 receptors regulates dendritic morphogenesis through Rac1 and RhoA in prefrontal cortex neurons, Mol. Neurobiol., 51, 1024, 10.1007/s12035-014-8762-1 Maccarrone, 2003, The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis, Cell Death Differ., 10, 946, 10.1038/sj.cdd.4401284 Mechoulam, R., Spatz, M., Shohami, E., 2002. Endocannabinoids and Neuroprotection. Science's STKE: Signal Transduction Knowledge Environment, 2002, re5. Nagayama, 1999, Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures, J. Neurosci.: Off. J. Soc. Neurosci., 19, 2987, 10.1523/JNEUROSCI.19-08-02987.1999 Piomelli, 2003, The molecular logic of endocannabinoid signalling, Nat. Rev. Neurosci., 4, 873, 10.1038/nrn1247 Quilter, 2012, Gene structure and expression of serotonin receptor HTR2C in hypothalamic samples from infanticidal and control sows, BMC Neurosci., 13, 37, 10.1186/1471-2202-13-37 Rao, 2006, Cannabinoid-mediated elevation of intracellular calcium: a structure-activity relationship, J. Pharmacol. Exper. Therapeut., 317, 820, 10.1124/jpet.105.100503 Tournier, 2016, Time-dependent effects of repeated THC treatment on dopamine D2/3 receptor-mediated signalling in midbrain and striatum, Behav. Brain Res., 311, 322, 10.1016/j.bbr.2016.05.045 Vogt, 2003, Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11, J. Biol. Chem., 278, 28743, 10.1074/jbc.M304570200