Effects of body fatness and physical activity on cardiovascular risk: Risk prediction using the bioelectrical impedance method

Scandinavian Journal of Public Health - Tập 34 Số 6 - Trang 568-575 - 2006
Susanna Calling1, Bo Hedblad1, Gunnar Engström1, Göran Berglund1, Lars Janzon1
1Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden

Tóm tắt

Aims: To explore the effects of body fat percentage (BF%) on incidence of and mortality from cardiovascular disease (CVD) and to study the cardio-protective effect of physical activity in relation to BF%. Methods: A total of 26,942 men and women, aged 45—73 years, without history of CVD were followed up for incidence of coronary events (CE), ischaemic stroke, and CVD mortality over seven years in relation to sex-specific quartiles (Q1—Q4) of BF%. The cardio-protective effect of leisure-time physical activity was studied in relation to BF%. Results: In men, the relative risk (RR) for CE and CVD mortality increased progressively with BF%. RR for CE in Q4 was 1.37 (95% confidence interval: 1.07—1.74), adjusted for age, height, smoking, high alcohol intake, and physical activity, compared with Q1. In women, BF% was significantly associated with incidence of CE and stroke. BF% was more strongly correlated to body mass index (BMI) (r=0.83) and waist circumference (r=0.76) in women than in men (r=0.59 and r=0.66, respectively). BF% was a stronger risk factor than BMI in women, and equally strong as waist circumference. A significant interaction (p=0.013 for incidence of CE, p=0.026 for ischaemic stroke) was found between BF% and sex. The raised cardiovascular risk was reduced by physical activity in subjects with high BF%. Conclusions: BF% is a risk factor for CE, ischaemic stroke, and CVD mortality. An interaction between BF% and sex suggests that BF% is a stronger CVD risk factor in women. The raised cardiovascular risk associated with high BF% is reduced by physical activity.

Từ khóa


Tài liệu tham khảo

10.1016/S0002-9149(02)02592-4

10.1038/sj.ijo.0802060

10.1210/jc.2004-0372

10.1093/ajcn/64.3.524S

Heitmann BL, 1994, Eur J Clin Nutr, 48, 228

10.1080/07315724.1999.10718862

10.1038/oby.2002.50

10.1097/00005768-199911001-00025

10.1146/annurev.pu.08.050187.001345

10.1002/j.1550-8528.1999.tb00714.x

10.1093/ajcn/69.3.373

10.1056/NEJMoa042135

10.1111/j.1365-2796.1993.tb00647.x

10.1097/00008469-200112000-00003

10.1001/jama.289.19.2560

Wallström P., 2002, Diet, lifestyle, antioxidants, and biomarkers of cancer risk: An epidemiological report from the Malmö Diet and Cancer cohort

10.1016/0021-9681(78)90058-9

The National Board of Health and Welfare., 2000, Värdering av diagnoskvaliteten för akut hjärtinfarkt i patientregistret 1997 och 1995 (Evaluation of quality of diagnosis of acute myocardial infarction, inpatient register 1997 and 1995, in Swedish)

The National Board of Health and Welfare., 1995, Centre of Epidemiology. Causes of death

10.1161/01.STR.23.3.357

1977, International Classification of Diseases, Ninth revision (ICD-9)

10.1161/01.STR.32.5.1098

10.1056/NEJM199908053410607

Menard S. Applied logistic regression analysis. Sage University Paper series no 07-106. Thousand Oaks, CA Sage Publications; 1995.

World Health Organization., 2000, Obesity: Preventing and managing the global epidemic. Report of a WHO consultation. Geneva, 3—5 June

10.1038/sj.ijo.0802545

10.1161/01.ATV.0000134293.31512.be

10.1093/aje/153.3.242

10.1056/NEJMoa033179

10.1016/0895-4356(94)90008-6

10.1056/NEJM199212313272701

Thông tin
Thông tin xuất bản

Scandinavian Journal of Public Health

Tập 34 Số 6

568-575

Thông tin tác giả