Effects of arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid on brain development using artificial rearing of delta-6-desaturase knockout mice

Akiko Harauma1, Erisa Hatanaka1, Hidemi Yasuda1, Manabu T. Nakamura2, Norman Salem3, Toru Moriguchi1
1School of Life and Environmental Science, Azabu University, 1-17-71, Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5201, Japan
2University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
3DSM Nutritional Products, Columbia, MD 21045, USA

Tài liệu tham khảo

Salem, 1996, Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants, Proc. Natl. Acad. Sci. USA, 93, 49, 10.1073/pnas.93.1.49 Brenna, 2007, Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide, Am. J. Clin. Nutr., 85, 1457, 10.1093/ajcn/85.6.1457 Hanebutt, 2008, Long-chain polyunsaturated fatty acid (LC-PUFA) transfer across the placenta, Clin. Nutr., 27, 685, 10.1016/j.clnu.2008.05.010 European Food Safety Authority (EFSA), Scientific opinion on the essential composition of infant and follow-on formulae, EFSA Journal, 12 3760, 2014. Brenna, 2016, Arachidonic acid needed in infant formula when docosahexaenoic acid is present, Nutr. Rev., 74, 329, 10.1093/nutrit/nuw007 Yasuda, 2016, Artificially reared mice exhibit anxiety-like behavior in adulthood, Exp. Anim., 65, 267, 10.1538/expanim.15-0115 Hatanaka, 2016, Essentiality of arachidonic acid intake in murine early development, Prostaglandins Leukot. Essent. Fat. Acids, 108, 51, 10.1016/j.plefa.2016.03.007 Harauma, 2017, The essentiality of arachidonic acid in addition to docosahexaenoic acid for brain growth and function, Prostaglandins Leukot. Essent. Fat. Acids, 116, 9, 10.1016/j.plefa.2016.11.002 Harauma, 2015, Effect of long-term administration of arachidonic acid on n-3 fatty acid deficient mice, Prostaglandins Leukot. Essent. Fat. Acids, 95, 41, 10.1016/j.plefa.2014.12.004 Moriguchi, 2000, Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration, J. Neurochem., 75, 2563, 10.1046/j.1471-4159.2000.0752563.x Moriguchi, 2003, Recovery of brain docosahexaenoate leads to recovery of spatial task performance, J. Neurochem., 87, 297, 10.1046/j.1471-4159.2003.01966.x Harauma, 2016, The influence of n−3 fatty acids on maternal behavior and brain monoamines in the perinatal period, Prostaglandins Leukot. Essent. Fat. Acids, 107, 1, 10.1016/j.plefa.2016.02.004 Castro, 2012, Functional desaturasefads1 (Δ5) and fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates, PLoS One, 7, e31950, 10.1371/journal.pone.0031950 Stoffel, 2008, Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids, EMBO J., 27, 2281, 10.1038/emboj.2008.156 Stroud, 2009, Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration, J. Lipid Res., 50, 1870, 10.1194/jlr.M900039-JLR200 Roqueta-Rivera, 2011, Deficiency in the omega-3 fatty acid pathway results in failure of acrosome biogenesis in mice, Biol. Reprod., 58, 721, 10.1095/biolreprod.110.089524 Takeuchi, 2001, Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout mice, J. Pharmacol. Exp. Ther., 297, 1160 Ohtsuka, 2011, ω-3 fatty acids attenuate mucosal inflammation in premature rat pups, J. Pediatr. Surg., 46, 489, 10.1016/j.jpedsurg.2010.07.032 Lim, 2005, N-3 fatty acid deficiency induced by a modified artificial rearing method leads to poorer performance in spatial learning tasks, Pediatr. Res., 4, 741, 10.1203/01.PDR.0000180547.46725.CC Greiner, 2003, Docosapentaenoic acid does not completely replace DHA in n-3 FA-deficient rats during early development, Lipids, 38, 431, 10.1007/s11745-003-1080-2 Carlson, 1996, Arachidonic acids status of human infants: influence of gestational age at birth and diets with very long chain n-3 and n-6 fatty acids, J. Nutr., 126, 1092S, 10.1093/jn/126.suppl_4.1092S