Effects of a Hepatitis C Virus Educational Intervention or a Motivational Intervention on Alcohol Use, Injection Drug Use, and Sexual Risk Behaviors Among Injection Drug Users

American journal of public health - Tập 99 Số S1 - Trang S180-S186 - 2009
William A. Zule1, Elizabeth C. Costenbader1, Curtis M. Coomes1, Wendee M. Wechsberg1
1At the time of this study, William A. Zule, Elizabeth C. Costenbader, Curtis M. Coomes, and Wendee M. Wechsberg were with the Behavioral Health Criminal Justice Research Division, RTI International, Research Triangle Park, North Carolina.

Tóm tắt

Objectives. We compared the effects of 2 interventions on alcohol use, use of a new syringe at last injection, and condom use at last sexual encounter in a community sample of injection drug users. Methods. Between 2003 and 2006, 851 out-of-treatment injection drug users were recruited in Raleigh, NC, and Durham, NC, through street outreach and were randomly assigned to either a 6-session educational intervention or a 6-session motivational intervention. Intervention effects were examined at 6 and 12 months after enrollment. Results. In multiple logistic regression analyses adjusted for baseline alcohol use and HCV status, participants assigned to the motivational intervention were significantly less likely than were participants in the educational intervention to be drinking at the 6-month follow-up (odds ratio = 0.67; 95% confidence interval = 0.46, 0.97). There were no significant between-group differences in use of a new syringe at last injection or condom use at last sexual encounter at either follow-up. Conclusions. Reducing alcohol use among persons with HCV may slow disease progression and provide important health benefits. Additional strategies are needed for slowing HCV disease progression until more effective HCV treatments are available.

Từ khóa


Tài liệu tham khảo

10.7326/0003-4819-144-10-200605160-00004

McHutchison JG, 2005, Am J Manag Care, 11, S286

10.1111/j.1530-0277.2006.00304.x

National Institutes of Health Consensus Development Conference Statement: Management of Hepatitis C. Bethesda, MD: National Institutes of Health; 2002.

10.1086/499960

10.1086/427440

10.1097/01.ede.0000135170.54913.9d

10.1111/j.1753-6405.2007.00007.x

10.1053/jhep.2002.35065

Wasley A, 2007, MMWR Surveill Summ, 56, 1

10.1086/427475

10.1097/QAD.0b013e3282ef7701

10.1016/j.arcmed.2006.09.002

10.1016/j.jhep.2007.07.016

10.1007/s10620-006-9669-0

10.1016/j.amjmed.2005.01.073

10.1176/ps.2006.57.4.570

10.1016/j.cld.2005.05.003

10.1016/j.annepidem.2004.12.006

10.1016/S1542-3565(05)00407-6

10.1111/j.1365-2893.2006.00764.x

10.1016/j.drugalcdep.2005.07.005

Office of Applied Studies, Substance Abuse and Mental Health Services Administration, US Department of Health and Human Services. Treatment Episode Data Set (TEDS), 2005 [computer file]. Prepared by Synectics for Management Decisions I. Treatment Episode Data Set (TEDS), 2005 [Computer file]. In: ICPSR04626-v1. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [producer and distributor]; 2007.

10.1016/S0740-5472(01)00198-2

Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: American Psychiatric Association; 1994.

10.1002/hep.20127

10.1016/j.annepidem.2007.01.012

Rubak S, 2005, Br J Gen Pract, 55, 305

10.1093/alcalc/agl016

10.1046/j.1360-0443.2002.00102.x

10.1080/09540129408258670

10.1037/0022-006X.71.5.843

10.1016/S0740-5472(01)00207-0

10.17730/humo.53.3.0889m4661142ngh1

10.2307/800824

10.1016/S1521-6918(03)00018-0

National Institute on Drug Abuse. The NIDA Community-Based Outreach Model: A Manual to Reduce the Risk of HIV and Other Blood-Borne Infections in Drug Users. Bethesda, MD: National Institute on Drug Abuse; 2000.

10.1097/MCG.0b013e3180381584

10.1023/A:1009555304568

10.1016/S0740-5472(01)00207-0

10.1016/j.drugalcdep.2007.01.006

Thông tin
Thông tin xuất bản

American journal of public health

Tập 99 Số S1

S180-S186

Thông tin tác giả