Effects of Thyroid Hormones on Bone and Mineral Metabolism

Adams, 1967, Bone and mineral metabolism in hyperthyroidism: An experimental study, Endocrinology, 81, 735, 10.1210/endo-81-4-735

Adams, 1967, Effects of hyperthyroidism on bone and mineral metabolism in man, G J Med, 36, 1

Adlin EV, Maurer AM, Marks AD, et al: Bone mineral density in postmenopausal Leif Mosekilde et al. women treated with thyroxine. Proceedings from the 63rd Meeting of the American Thyroid Association, 1988, p 17

Askanazy, 1933, Die Knochen der Basedow-Kranken, Virchows Arch Pathol Anat, 291, 653, 10.1007/BF01891731

Aub, 1929, Studies of calcium and phosphorus metabolism, III. The effects of the thyroid hormone and thyroid disease. J Clin Invest, 7, 97

Auwerx, 1986, Mineral and bone metabolism in thyroid disease: A review, Q J Med, 232, 737

Baxter, 1966, Hypercalcemia of thyrotoxicosis, Ann Intern Med, 65, 429, 10.7326/0003-4819-65-3-429

Bayley, 1980, Effect of thyrotoxicosis and its treatment on bone mineral and muscle mass, J Clin Endocrinol Metab, 50, 916, 10.1210/jcem-50-5-916

Bernal, 1980, Mode of action of thyroid hormones, 123

Bijlsma, 1983, Thyroid function and bone turnover, Acta Endocrinol, 104, 42, 10.1530/acta.0.1040042

Bijvoet, 1969, Relation of plasma phosphate concentration to renal tubular reabsorption of phosphate, Clin Sei, 37, 23

Bijvoet, 1965, The renal tubular reabsorption of phosphate in thyrotoxi cosis, Clin Chim Acta, 11, 181, 10.1016/0009-8981(65)90213-5

Bijvoet, 1968, Effects of calcitonin on patients with Paget's disease, thyrotoxicosis and hypercalcaemia, Lancet, 1, 876, 10.1016/S0140-6736(68)90236-5

Body, 1986, Calcitonin deficiency in primary hypothyroidism, J Clin Endocrinol Metab, 62, 700, 10.1210/jcem-62-4-700

Bordier, 1967, Bone changes in adult patients with abnormal thyroid function (with special reference to Ca kinetics and quantitative histology), Proc R Soc Med, 60, 26

Bouillon, 1974, Parathyroid function in patients with hyper- or hypothyroidism, J Clin Endocrinol Metab, 38, 999, 10.1210/jcem-38-6-999

Bouillon, 1980, Influence of thyroid function on the serum concentration of 1,25-dihydroxy vitamin D3, J Clin Endocrinol Metab, 51, 793, 10.1210/jcem-51-4-793

Boyle, 1973, The biological activity and metabolism of 24,25-dihydroxy vitamin D3, J Biol Chem, 248, 4174, 10.1016/S0021-9258(19)43754-X

Bradley, 1974, The thyroid and the kidney, Kidney Int, 6, 346, 10.1038/ki.1974.119

Braid, 1951, Hypothyroidism in childhood, Br Med J, 1, 1169, 10.1136/bmj.1.4716.1169

Brixen, 1989, Efficacy of wheat germ lectin-precipitated alkaline phosphatase in serum as an estimator of bone mineralization rate: Comparison to serum total alkaline phosphatase and serum bone GLA-protein, Calcif Tissue Int, 44, 93, 10.1007/BF02556467

Brown, 1984, Serum bone Gla-protein: A specific marker for bone formation in postmenopausal osteoporosis, Lancet, 1, 1091, 10.1016/S0140-6736(84)92506-6

Buckle, 1969, Thyrotoxic hypercalcaemia treated with porcine calcitonine, Lancet, 1, 1128, 10.1016/S0140-6736(69)91646-8

Burkinshaw, 1969, Bone turnover model based on a continuous expanding exchangeable calcium pool, Nature, 222, 146, 10.1038/222146a0

Cannigia, 1971, Absorption du phosphate radioactif chez l'homme et sa regulation

Cassar, 1969, Alkaline phosphatase levels in thyroid disease, Clin Chim Acta, 23, 33, 10.1016/0009-8981(69)90007-2

Castro, 1975, Comparative response to parathyroid hormone in hyperthyroidism and hypothyroidism, Metabolism, 24, 839, 10.1016/0026-0495(75)90130-4

Charles, 1983, Calcium metabolism evaluated by 47-Calcium kinetics: Estimation of dermal calcium loss, Clin Sei, 65, 415, 10.1042/cs0650415

Charles, 1985, Estimation of bone turnover evaluated by 47Ca-kinetics, Efficiency of serum bone gamma-carboxyglutamic acid-containing protein, serum alkaline phosphatase, and urinary hydroxyproline excretion. J Clin Invest, 76, 2254

Charles, 1987, Bone turnover and balance evaluated by combined calcium balance and 47Calcium kinetic study and dynamic histomorphometry, Metabolism, 36, 1118, 10.1016/0026-0495(87)90237-X

Cleeve, 1978, Plasma 25-hydroxyvitamin D and alkaline phosphatase isoenzymes in hyperthyroidism, Ann Clin Biochem, 15, 320, 10.1177/000456327801500176

Cohn, 1973, Alterations in elemental body composition in thyroid disorders, J Clin Endocrinol Metab, 36, 742, 10.1210/jcem-36-4-742

Coindre, 1985, Bone loss in hypothyroidism with hormonal replacement: A histomorphometric study, Arch Intern Med, 146, 48, 10.1001/archinte.1986.00360130058007

Cook, 1959, The effects of thyrotoxicosis upon the metabolism of calcium, phosphorus and nitrogen, Q J Med, 28, 505

Cooper, 1979, Alkaline phosphatase isoenzyme patterns in hyperthyroidism, Ann Intern Med, 90, 164, 10.7326/0003-4819-90-2-164

Dent, 1956, Cortisone test for hyperparathyroidism, Br Med J, 1, 230, 10.1136/bmj.1.4960.230-a

Eriksen, 1986, Normal and pathological remodeling of human trabecular bone: Three dimensional reconstruction of the remodeling sequence in normals and in metabolic bone disease, Endocr Rev, 7, 379, 10.1210/edrv-7-4-379

Eriksen, 1984, Reconstruction of the resorptive site in iliac trabecular bone: A kinetic model for bone resorption in 20 normal individuals, Metab Bone Dis Rel Res, 5, 235, 10.1016/0221-8747(84)90065-1

Eriksen, 1986, Kinetics of trabecular bone resorption and formation in hypothyroidism: Evidence for a positive balance per remodeling cycle, Bone, 7, 101, 10.1016/8756-3282(86)90681-2

Eriksen, 1985, Trabecular bone remodeling and bone balance in hyperthyroidism, Bone, 6, 421, 10.1016/8756-3282(85)90218-2

Epstein, 1958, Hypercalcemia, nephrocalcinosis and reversible renal insufficiency associated with hyperthyroidism, N Engl J Med, 258, 782, 10.1056/NEJM195804172581604

Faber J, Johansen J, Perrild H: Bone Gla protein (BGP) and sex hormone binding globulin (SHBG) in non toxic goiter, parameters for the metabolic status at the tissue level. Proceedings from the 63rd Meeting of the American Thyroid Association 1988, p 23

Farley, 1982, Purification of a skeletal growth factor from human bone, Biochemistry, 21, 3502, 10.1021/bi00257a037

Feely, 1981, Propranolol and the hypercalcaemia of thyrotoxicosis, Acta Endocrinol, 98, 528, 10.1530/acta.0.0980528

Follis, 1953, Skeletal changes associated with hyperthyroidism, Bull Johns Hopkins Hosp, 92, 405

Fraser, 1971, Osteoporosis and fractures following thyrotoxicosis, Lancet, 1, 981, 10.1016/S0140-6736(71)91383-3

Fraser, 1970, The effect on bone of thyrotoxicosis and its treatment, 497

Friedland, 1965, Effect of hyperthyroidism on intestinal calcium absorption in the rat, Proc Soc Exp Biol Med, 120, 20, 10.3181/00379727-120-30432

Fritzel, 1967, Plasma levels of ionized calcium and magnesium in thyroid disease, Lancet, 1, 1360, 10.1016/S0140-6736(67)91766-7

Frost, 1964, Dynamics of bone remodeling

Frost, 1964

Frost, 1965, A synchronous group of mammalian cells, whose in vivo behaviour can be studied, Henry Ford Med Bull, 13, 161

Gaspard, 1978, Serum somatomedin stimulation in thyroxin-treated hypophysectomized rats, Endocrinology, 102, 606, 10.1210/endo-102-2-606

Gordon, 1974, The serum calcium level and its significance in hyperthyroidism: A prospective study, Am J Med Sei, 268, 31, 10.1097/00000441-197407000-00004

Greenberg AH, Najjar S, Blizzard RM: Effects of thyroid hormone on growth differen tiation and development. In Greer MA, Solomon DH (eds): Handbook of Physiology. Washington DC, American Physiological Society, 1974, Sect 7:3, p 377

Haldimann, 1980, Intestinal absorption in patients with hyperthyroidism, J Clin Endocrinol Metab, 51, 995, 10.1210/jcem-51-5-995

Harrison, 1964, Some effects of parathyroid hormone in thyrotoxicosis, J Clin Endocrinol Metab, 24, 214, 10.1210/jcem-24-2-214

Hasling, 1987, Exogenous triiodothyronine activates bone remodeling, Bone, 8, 65, 10.1016/8756-3282(87)90072-X

Hattner, 1965, Kinetics of osteoclasts and their nuclei in evolving secondary Haversian systems, J Anat, 133, 397

Hendrikx, 1979, Investigation of bone and mineral metabolism in hyperthy roidism before and after treatment using 47Ca and balance studies, Acta Endocrinol, 91, 77, 10.1530/acta.0.0910077

Heyma, 1980, Inhibition by propranolol of 3,5,3'-triiodothyro nine formation from thyroxine in isolated rat renal tubules: An effect independent of ß-adrenergic blockade, Endocrinology, 106, 1437, 10.1210/endo-106-5-1437

Hunter, 1930, The significance to clinical medicine of studies in calcium and phosphorus metabolism, Lancet, 1, 947

Huth, 1959, Hyperthyroidism associated with renal tubular acidosis, Am J Med, 26, 818, 10.1016/0002-9343(59)90240-2

Jastrup, 1982, Serum levels of vitamin D metabolites and bone remodelling in hyperthyroidism, Metabolism, 32, 126, 10.1016/0026-0495(82)90123-8

Jaworsky, 1971, Some morphologic and dynamic aspects of remodelling on the endosteal-cortical and trabecular surfaces, 159

Jaworsky, 1976, The effects of moderate uremia and high phosphate normal calcium diet on the linear erosion rate measured in the Haversian turnover sites in the rib of the adult dog, 148

Jensen, 1983, Calcium metabolism evaluated by ^Calcium-kinetics: a physiological model with correction for faecal lag time and estimation of dermal calcium loss, Clin Physiol, 3, 187, 10.1111/j.1475-097X.1983.tb00690.x

Jones, 1979, Control of hypercalcaemia in thyrotoxicosis, Postgrad Med J, 55, 891, 10.1136/pgmj.55.650.891

Jowsey, 1969, Importance of thyroid hormones in bone metabolism and calcium homeostasis, Endocrinology, 85, 87, 10.1210/endo-85-1-87

Kano, 1981, Direct in vitro effect of thyroid hormones on 25-hydroxyvitamin D3 metabolism in perfused rat kidney, Endocrinology, 114, 330, 10.1210/endo-114-2-330

Karlberg, 1974, Cyclic adenosine 3',5'-monophosphate concentration in plasma adipose tissue and skeletal muscle in normal subjects and in patients with hyper- and hypothyroidism, J Clin Endocrinol Metab, 39, 96, 10.1210/jcem-39-1-96

Karsenty, 1985, Elevated metabolic clearance rate of 1,25-dihydroxy vitamin D3 in hyperthyroidism, Acta Endocrinol, 110, 70, 10.1530/acta.0.1100070

Kivirikko, 1965, Value of urine and serum hydroxyproline in the diagnosis of thyroid disease, J Clin Endocrinol Metab, 25, 1347, 10.1210/jcem-25-10-1347

Kleeman, 1958, Metabolic observations in case of thyrotoxicosis with hypercalcaemia, J Clin Endocrinol Metab, 18, 477, 10.1210/jcem-18-5-477

Klein, 1964, Correlation of urinary hydroxyproline, serum alkaline phosphatase and skeletal calcium turn-over, Metabolism, 13, 272, 10.1016/0026-0495(64)90106-4

Kragstrup, 1983, Thickness of bone formed at remodeling sites in normal iliac trabecular bone: Variation with age and sex, Metab Bone Dis Rel Res, 5, 17, 10.1016/0221-8747(83)90046-2

Kragstrup, 1981, Effect of thyroid hormones on mean wall thickness of trabecular bone packets, Metab Bone Dis Rel Res, 2, 13

Krane, 1956, The effect of thyroid disease on calcium metabolism in man, J Clin Invest, 35, 874, 10.1172/JCI103340

Krawitt, 1967, Duodenal calcium transport in hyperthyroidism, Proc Soc Exp Biol, 125, 417, 10.3181/00379727-125-32108

Krplner, 1983, Spinal bone mineral content in myxoedema and thyrotoxicosis, Effects of thyroid hormones and antithyroid treatment. Clin Endocrinol, 18, 439

Laitinen, 1975, Clinical application of urinary hydroxyproline determination, Acta Med Scand, 577, 8

Lekkerkerker, 1971, Enhancement of calcium absorption in hypothyroidism, Isr J Med Sei, 7, 399

Lim, 1969, Handling of induced hypercalcemia in hyperthyroidism, Br Med J, 4, 715, 10.1136/bmj.4.5685.715

Lowe, 1962, Hypercalcemia in myxoedema, J Clin Endocrinol Metab, 22, 261, 10.1210/jcem-22-3-261

Lukert BP, Higgins JC, Stoskopf MM: Serum osteocalcin in patients with hyperthyroid ism and Cushing's syndrome. Abstract of the 7th meeting of the American Bone and Mineral Research 1985, p 199

Lund, 1980, Stimulation of 1,25-dihydroxyvitamin D production by parathyroid hormone and hypocalcemia in man, J Clin Endocrinol Metab, 50, 480, 10.1210/jcem-50-3-480

Macfarlane, 1982, Vitamin D metabolism in hyperthyroidism, Clin Endocrinol, 17, 51, 10.1111/j.1365-2265.1982.tb02633.x

Malamos, 1969, The renal handling of phosphate in thyroid disease, J Endocrinol, 45, 269, 10.1677/joe.0.0450269

Mandelier, 1974, Etude de la fonction parathyroidienne dans l'hyperthyroidie, Ann Endocrinol (Paris), 35, 185

Manicourt, 1979, Disturbed mineral metabolism in hyperthyroidism: Good correlation with triiodothyronine, Clin Endocrinol, 10, 407, 10.1111/j.1365-2265.1979.tb02096.x

Manicourt, 1979, Les perturbations du métabolism phosphocalcique dans l'hyperthyroidie, Brux Med, 59, 489

Marcus, 1975, Cyclic nucleotide phosphodiesterase from bone: Characterization of the enzyme and studies of inhibition by thyroid hormones, Endocrinology, 96, 400, 10.1210/endo-96-2-400

Martin, 1953, The calcium binding of human serum albumin in health and disease, Biochem J, 54, 642, 10.1042/bj0540642

Meema, 1972, Comparison of microradioscopic and morphometric findings in the hand bones with densitometric findings in the proximal radius in thyreotoxicosis and renal osteodystrophy, Invest Radiol, 7, 88, 10.1097/00004424-197203000-00004

Meema, 1970, Simple radiologic demonstrations of cortical bone loss in thyrotoxicosis, Radiology, 97, 9, 10.1148/97.1.9

Meisen, 1977, Morphometric and dynamic studies of bone changes in hyperthyroidism, Acta Pathol Microbiol Scand [A], 85, 141

Meisen, 1983, Metabolic bone disease as evaluated by bone histomorphometry, 109

Meunier, 1972, Bony manifestations of thyrotoxicosis, Orthop Clin North Am, 3, 745, 10.1016/S0030-5898(20)30490-9

Mindroiu, 1974, The intestinal calcium absorption in thyroid dysfunction, Rev Rhum Med, 12, 119

Mosekilde L: Effect of Thyroid Hormone(s) on Bone Remodelling, Bone Mass and Calcium-Phosphorus Homeostasis in Man. Thesis, University of Arhus, Denmark, 1979

Mosekilde, 1977, Decreased parathyroid function in hyperthyroidism: Interrelationships between serum parathyroid hormone, calcium-phosphorus metabolism and thyroid function, Acta Endocrinol, 84, 566, 10.1530/acta.0.0840566

Mosekilde, 1978, Effect of antithyroid treatment on calcium-phosphorus metabolism in hyperthyroidism, I. Chemical quantities in serum and urine. Acta Endocrinol, 87, 743, 10.1530/acta.0.0870743

Mosekilde, 1984, Effect of propranolol treatment on bone mass, bone mineral content, bone remodelling, parathyroid function and vitamin D metabolism in hyperthyroidism, Eur J Clin Invest, 14, 96, 10.1111/j.1365-2362.1984.tb02095.x

Mosekilde, 1977, Serum 25-hydroxycholecalciferol in hyper thyroidism, Lancet, 1, 806, 10.1016/S0140-6736(77)92995-6

Mosekilde, 1978, Morphometric and dynamic studies of bone changes in hypothyroidism, Acta Pathol Microbiol Scand [A], 86, 56

Mosekilde, 1978, A tetracycline based histomorphometric evaluation of bone resorption and bone turn-over in hyperthyroidism and hyperparathyroidism, Acta Med Scand, 204, 97, 10.1111/j.0954-6820.1978.tb08406.x

Mosekilde, 1978, Effect of antithyroid treatment on calcium-phosphorus metab olism in hyperthyroidism, II. Bone histomorphometry. Acta Endocrinol, 87, 751, 10.1530/acta.0.0870751

Mosekilde, 1977, Bone changes in hyperthyroidism: Interrela tionships between bone morphometry, thyroid function and calcium-phosphorus metabolism, Acta Endocrinol, 85, 515, 10.1530/acta.0.0850515

Mosekilde, 1987, Biomechanical competence of vertebral trabecular bone in relation to ash density and age in normal individuals, Bone, 8, 79, 10.1016/8756-3282(87)90074-3

Mundy, 1976, Direct stimulation of bone resorption by thyroid hormones, J Clin Invest, 58, 529, 10.1172/JCI108497

Nielsen, 1952, The bony system in hyperthyroidism, Acta Med Scand, 266, 783, 10.1111/j.0954-6820.1952.tb13427.x

Nielsen, 1979, Bone mineral content in hyperthyroid patients after combined medical and surgical treatment, Acta Radiol Oncol, 18, 122

Noble, 1967, The effect of thyroxine on the movement of calcium and inorganic phosphate through the small intestine of the rat, J Endocrinol, 37, 111, 10.1677/joe.0.0370111

Parfitt, 1982, The coupling of bone formation and bone resorption: A critical analysis of the concept and of its relevance to the pathogenesis of osteoporosis, Metab Bone Dis Rel Res, 4, 1, 10.1016/0221-8747(82)90002-9

Parfitt, 1984, Age related structural changes in trabecular and cortical bone. Cellular mechanisms and biomechanical consequences, Calcif Tissue Int, 26, S123, 10.1007/BF02406145

Parfitt, 1970, Hyperthyroidism and hypercalcemia, Q J Med, 39, 171

Parson, 1964, The maximum renal tubular reabsorptive rate for inorganic phosphate in thyrotoxicosis, Clin Sei, 27, 313

Pavlovitch, 1977, Decreased bone sensitivity of thyroidectomized rats to the calcemic effect of 1,25-dihydroxycholecalciferol, Acta Endocrinol, 84, 774, 10.1530/acta.0.0840774

Peacock, 1977, Effect of vitamin D metabolites on proximal muscle weakness, Calcif Tissue Res, 24, 20

Raisz, 1983, Regulation of bone formation, Part II, N Engl J Med, 309, 83, 10.1056/NEJM198307143090206

Rasmussen, 1974

Richards, 1970, Hypercalcaemia in thyrotoxicosis with and without hyperparathyroidism, Postgrad Med J, 46, 440, 10.1136/pgmj.46.537.440

Rikushi, 1977, Radioimmunoassay of human calcitonin in thyroid disease, Calcif Tissue Res, 23, 204

Robertson, 1942, Calcium and phosphorus excretion in thyrotoxicosis and myxoedema, Lancet, 1, 672, 10.1016/S0140-6736(00)70212-1

Ross, 1987, Subclinical hyperthyroidism and reduced bone density as a possible result of prolonged suppression of the pituitary-thyroid axis with L-thyroxine, Am J Med, 82, 1162, 10.1016/0002-9343(87)90219-1

Royer, 1958, Les hypercalcemies et les nephrocalcinoses ou cours du myxoedeme congénital, Arch Fr Pediatr, 15, 896

Royer, 1968, Troubles du métabolism calcique dans l'insuffisance thyroidienne de Tenfant, Ann Endocrinol (Paris), 29, 610

Rude, 1976, Treatment of thyrotoxic hypercalcemia with propranolol, N Engl J Med, 294, 431, 10.1056/NEJM197602192940807

Ryckewaert, 1968, L'ostéose thyroidienne, Sem Hop Paris, 4, 222

Sallin, 1958, Hypercalcemic nephropathy in thyreotoxicosis, Acta Endocrinol, 29, 425, 10.1530/acta.0.0290425

Sedlin, 1963, Variations in cross section area of rib cortex with age, J Gerontol, 18, 9, 10.1093/geronj/18.1.9

Shafer, 1972, Calcium malabsorption in hyperthyroidism, Gastroenterology, 63, 235, 10.1016/S0016-5085(19)33308-6

Siersbaek-Nielsen, 1971, Hydroxyproline excretion in the urine and calcium metabolism during long-term treatment of thyrotoxicosis with propylthiouracil, Acta Med Scand, 189, 485, 10.1111/j.0954-6820.1971.tb04409.x

Silva, 1978, Calcitonin in thyroidectomized patients, Am J Med Sei, 275, 159, 10.1097/00000441-197803000-00005

Simpson, 1950, Some endocrine influences on skeletal growth and differentiation, Yale J Biol Med, 23, 1

Singhelakis, 1974, Intestinal calcium absorption in hyperthyroidism, Metabolism, 23, 311, 10.1016/0026-0495(74)90049-3

Smith, 1973, Hyperthyroidism and calcium metabolism, Clin Endocrinol Metab, 2, 333, 10.1016/S0300-595X(73)80047-7

Strache, 1986, Local production of insulin like growth factor in bone under the influence of growth hormone and thyroid hormones, J Bone Min Res, 1, 99

Swaminathan, 1975, The effect of thyroxine administration on intestinal calcium absorption and calcium binding protein activity in the chick, Calcif Tissue Res, 17, 257, 10.1007/BF02546689

Tadayyon, 1969, Interrelationship of triglyceride with calcium, magnesium and phosphorus in the rat, J Nutr, 97, 246, 10.1093/jn/97.2.246

Tuwross, 1970, Symptomatic hypercalcemia in thyrotoxicosis, Br Med J, 2, 701, 10.1136/bmj.2.5711.701

Velentzas, 1977, Vitamin D levels in thyrotoxicosis, Lancet, L370

Williams, 1967, Calcium-47 absorption in rats with induced hyperthyroidism, Isr J Med Sei, 3, 639

Wilkinson, 1976, Absorption of calcium, phosphorus and magnesium, 36

Zanatta, 1984, Parathyroid hormone and calcitonin in thyrotoxicosis, Horm Metab Res, 16, 384, 10.1055/s-2007-1014800