Effects of Redox Couple on the Response of Polypyrrole‐Based Electrochemical DNA Sensors

Electroanalysis - Tập 24 Số 6 - Trang 1311-1317 - 2012
Marsilea A. Booth1, SallyAnn Harbison2, Jadranka Travaš-Sejdić3,1
1Polymer Electronics Research Centre (PERC), University of Auckland, Private Bag – 92019, Auckland, New Zealand tel:+64 9 373 7599 ext. 88272
2Institute of Environmental Science Research Ltd.(ESR), Private Bag 92-021, Auckland, New Zealand
3MacDiarmid Institute for Advanced Materials and Nanotechnology, New Zealand

Tóm tắt

AbstractMuch research‐to‐date exists to create sensitive and selective DNA sensors. A variety of approaches are adopted, including those involving polypyrrole and electrical impedance spectroscopy. Combined these are able to sense as well as aptly transduce signals. Many such sensors employ ferri/ferrocyanide to exhibit surface hybridization. This redox reporter, though with merits, can prove disadvantageous. To this end, a comparative study was performed with the redox reporter hydroquinone. For comparison purposes ferri/ferrocyanide indicated greater sensitivity, suggested to arise from inherent charge. Conversely, with hydroquinone steric hindrance is the main influencing factor. Such a study aims to guide design of analogous sensors.

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Thông tin
Thông tin xuất bản

Electroanalysis

Tập 24 Số 6

1311-1317

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