Effects of Genetic Variability on Rifampicin and Isoniazid Pharmacokinetics in South African Patients with Recurrent Tuberculosis

Pharmacogenomics - Tập 20 Số 4 - Trang 225-240 - 2019
Anushka Naidoo1, Maxwell Chirehwa2, Veron Ramsuran3,4, Helen McIlleron2, Kogieleum Naidoo5,6, Nonhlanhla Yende‐Zuma1, Ravesh Singh7, Sinaye Ngcapu1, John Adamson8, Katya Govender8, Paolo Denti2, Nesri Padayatchi5,6
1Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa
2Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa
3Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa KwaZulu-Natal Research Innovation & Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa
4KwaZulu-Natal Research Innovation & Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa
5Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa MRC-CAPRISA HIV-TB Pathogenesis & Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa
6MRC-CAPRISA HIV-TB Pathogenesis & Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa
7Department of Microbiology, National Health Laboratory Services, KZN Academic Complex, Inkosi Albert Luthuli Central Hospital, Durban, South Africa
8Pharmacology Core, Africa Health Research Institute (AHRI), Durban, South Africa

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