Effects of Fibrotic Tissue on Liver-targeted Hydrodynamic Gene Delivery

Molecular Therapy - Nucleic Acids - Tập 5 - Trang e359 - 2016
Yuji Kobayashi1, Kenya Kamimura1, Hiroyuki Abe1, Takeshi Yokoo1, Kohei Ogawa1, Yoko Shinagawa-Kobayashi1, Ryo Goto1, Ryosuke Inoue1, Masato Ohtsuka2,3, Hiromi Miura4, Tsutomu Kanefuji1, Takeshi Suda1, Masanori Tsuchida5, Yutaka Aoyagi1, Guisheng Zhang6, Dexi Liu6, Shuji Terai1
1Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Niigata, Japan
2Department of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, School of Medicine, Tokai University, Isehara, Kanagawa, Japan
3The Institute of Medical Sciences, Tokai University, Isehara, Kanagawa Japan
4Department of Regenerative Medicine, Basic Medical Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan
5Division of Thoracic and Cardiovascular Surgery, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Niigata, Japan
6Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, USA

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