Ảnh hưởng của Cr Methionine đến Chuyển hóa Glucose, Chất chuyển hóa Huyết tương, Oxy hóa Lipid Thịt, và Nồng độ Crom trong Các con Dê Mahabadi

Biological Trace Element Research - Tập 164 - Trang 50-57 - 2014
A. Emami1, M. Ganjkhanlou2, A. Zali2
1Department of Animal Science, University of Birjand, Birjand, Iran
2Department of Animal Science, University of Tehran, Karaj, Iran

Tóm tắt

Nghiên cứu này được thiết kế để điều tra ảnh hưởng của crom methionine (Cr–Met) đến chuyển hóa glucose, các chất chuyển hóa trong máu, sự oxy hóa lipid thịt, và nồng độ crom (Cr) trong mô của các con dê con Mahabadi. Ba mươi hai con dê con đực (16,5 ± 2,8 kg BW, 4–5 tháng tuổi) đã được nuôi trong 90 ngày theo thiết kế ngẫu nhiên hoàn toàn với bốn phương pháp điều trị. Các phương pháp điều trị được bổ sung với 0 (nhóm đối chứng), 0,5, 1 và 1,5 mg Cr dưới dạng Cr–Met/động vật/hằng ngày. Mẫu máu được thu thập qua ống heparin từ tĩnh mạch cổ ở ngày 0, 21, 42, 63 và 90 của thí nghiệm. Vào ngày 70, một thử nghiệm dung nạp glucose tĩnh mạch (IVGTT) đã được thực hiện. Cuối thử nghiệm cho ăn, các con dê được mổ thịt và mẫu gan, thận, và cơ dài (LD) được thu thập. Nồng độ glucose, insulin, và triglyceride trong huyết tương đã giảm nhờ bổ sung Cr (P < 0,05). Malondialdehyde (MDA) trong cơ LD đã giảm, và nồng độ Cr trong huyết tương và mô đã tăng cùng với việc tăng mức bổ sung Cr (P < 0,05). Nồng độ glucose trong huyết tương ở 30 và 60 phút sau khi truyền glucose thấp hơn ở các con dê được cho ăn chế độ ăn 1,5 mg Cr so với các con dê ăn chế độ đối chứng (P < 0,05). IVGTT cho thấy rằng các con dê được bổ sung 1,5 mg Cr có tỷ lệ thanh thải glucose (K) cao hơn và thời gian bán hủy glucose (T½) thấp hơn (P < 0,05). Diện tích dưới đường cong phản ứng glucose (AUC) từ 0 đến 180 phút sau khi truyền glucose đã giảm theo cách tuyến tính (P < 0,01) khi có bổ sung Cr. Kết quả cho thấy rằng Cr bổ sung có thể cải thiện khả năng sử dụng glucose và oxy hóa lipid của thịt ở các con dê con đang nuôi béo.

Từ khóa


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