Effects of Bergamottin on Human and Monkey Drug-Metabolizing Enzymes in Primary Cultured Hepatocytes

Ameer, 1997, Drug interactions with grapefruit juice., Clin Pharmacokinet, 33, 103, 10.2165/00003088-199733020-00003

Bailey, 1993, Grapefruit juice-felodipine interaction: mechanism, predictability and effect of naringin., Clin Pharmacol Ther, 53, 637, 10.1038/clpt.1993.84

10.1016/S0009-9236(98)90173-4

10.1046/j.1365-2125.1998.00764.x

10.1016/0140-6736(91)90872-M

10.1016/S0960-894X(97)10043-9

10.1021/tx950208b

10.1006/abbi.1994.1259

Dakovic, 1999, The activity of liver oxidative enzymes after single and multiple grapefruit juice ingestion., Exp Toxicol Pathol, 51, 304, 10.1016/S0940-2993(99)80011-6

10.1016/0009-9236(95)90032-2

10.1046/j.1365-2125.1999.00052.x

Edwards, 1996, Identification of 6′, 7′-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice., Drug Metab Dispos, 24, 1287

10.1016/0024-3205(96)00417-1

10.1016/S0009-9236(99)70102-5

10.2165/00002018-199818040-00002

Fukuda, 2000, Amounts and variation in grapefruit juice of the main components causing grapefruit-drug interaction., J Chromatogr B Biomed Appl, 741, 195, 10.1016/S0378-4347(00)00104-3

Fukuda, 1997, Specific CYP3A4 inhibitors in grapefruit juice: furocoumarin dimers as components of drug interaction., Pharmacogenetics, 7, 391, 10.1097/00008571-199710000-00008

Guo, 2000, Role of furancoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity., Drug Metab Dispos, 28, 766

10.1021/tx970192k

Hostetler, 1989, Coinduction of multiple hepatic cytochrome P450 proteins and their mRNAs in rats treated with imidazole antimycotic agent., Mol Pharmacol, 35, 279

Kane, 2001, Assessment of the sensitivity and specificity of oligonucleotide (50mer) microarray., Nucleic Acids Res, 128, 4552

Kostrubsky, 1999, The use of human hepatocyte cultures to study the induction of cytochrome P-450., Drug Metab Dispos, 27, 887

10.1016/0009-9236(95)90068-3

Lown, 1997, Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression., J Clin Invest, 99, 2545, 10.1172/JCI119439

Lowry, 1951, Protein measurement with the Folin phenol reagent., J Biol Chem, 193, 265, 10.1016/S0021-9258(19)52451-6

10.1023/A:1011028401189

Mohri, 2000, Effects of long-term grapefruit juice ingestion on nifedipine pharmacokinetics: induction of rat hepatic P-450 by grapefruit juice., Drug Metab Dispos, 28, 482

10.1016/0003-2697(80)90505-9

Ranganna, 1983, Citrus fruits–varieties, chemistry, technology, and quality evaluation. Part II. Chemistry, technology and quality evaluation. A. Chemistry., Crit Rev Food Sci Nutr, 18, 313, 10.1080/10408398309527366

Rashid, 1995, Factors affecting the absolute bioavailability of nifedipine., Br J Clin Pharmacol, 40, 51, 10.1111/j.1365-2125.1995.tb04534.x

10.1124/dmd.30.2.135

Schmiedlin-Ren, 1997, Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarines., Drug Metab Dispos, 27, 1415

10.1023/A:1011902625609

10.1016/S0928-0987(00)00191-3

Steinberg, 1999, Drug metabolizing capacity of cryopreserved human, rat and mouse liver parenchymal cells in suspension., Drug Metab Dispos, 25, 1228

Strom SC Dorko K Thompson MT Pisarov LA Nusler AK (1998) Large scale isolation and culture of human hepatocytes. Llots de Landerhans et hepatocytes. in Vers une utilisation therapeutique, eds Franco D Boudjema K Varet B (Institut National de la Sante et de la Recherche Medicale, Paris), pp 195–205.

Strom, 1996, Use of human hepatocytes to study P450 gene induction., Methods Enzymol, 272, 388, 10.1016/S0076-6879(96)72044-X

Takanaga, 1998, Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in Caco-2 cells., Biol Pharm Bull, 21, 1062, 10.1248/bpb.21.1062

10.1006/abbi.2000.1835

10.1021/bi00330a010