Effects of Azaspiracids 2 and 3 on Intracellular cAMP, [Ca2+], and pH

Chemical Research in Toxicology - Tập 17 Số 10 - Trang 1338-1349 - 2004
Yolanda Román1, Amparo Alfonso1, Mercedes R. Vieytes1, Katsuya Ofuji1, Masayuki Satake1, Takeshi Yasumoto1, Luís M. Botana1
1Departamentos de Farmacología and Departamento de Fisiología, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan, and Japan Food Research Laboratories, Tama, Tokyo 206-0025, Japan

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Ofuji K., 1999, Nat. Toxins, 7, 102

Ofuji K., 2001, Biotechnol., Biochem. 65, 740−742.

Furey A., 2002, Determination of azaspiracids in shellfish using liquid chromatography/tandem electrospray mass spectrometry. Rapid Commun. Mass Spectrom. 16, 238−242

James K. J., 2003, Detection of five new hydroxyl analogues of azaspiracids in shellfish using multiple tandem mass spectrometry. Toxicon 41, 277−283

Ito E., 2000, Multiple organ damage caused by a new toxin, azaspiracid, isolated from mussels produced in Ireland. Toxicon 38, 917−930

Ito E., 2002, Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels. Toxicon 40, 193−203, 10.1016/S0041-0101(01)00226-4

Román Y., 2002, Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets. Cell. Signalling 14

James K. J., 2002, First evidence of an extensive northern European distribution of azaspiracid poisoning (AZP) toxins in shellfish. Toxicon 40, 909−915

Magdalena A. B., 2003, The first identification of azaspiracids in shellfish from France and Spain. Toxicon 42, 105−108

de La Rosa L. A., 2002, Naunyn Schmiedeberg's Arch. Pharmacol., 365, 81, 10.1007/s00210-002-0607-1

de la Rosa L. A., 2001, Ca(2+) channel blockers and kinases. Cell. Signalling 13, 711−716.

de la Rosa L. A., 2001, Modulation of cytosolic calcium levels of human lymphocytes by yessotoxin, a novel marine phycotoxin. Biochem. Pharmacol. 61, 827−833

Leira F., 2002, Biochem. Pharmacol. 63

Grynkiewicz G., 1985, J. Biol. Chem., 260, 10.1016/S0021-9258(19)83641-4

Thomas J. A., 1979, Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18, 2210−2218

Adams S. R., 1991, Fluorescence ratio imaging of cyclic AMP in single cells. Nature 349, 694−697

Lee C. H., 2002, Am. J. Physiol. Heart Circ. Physiol., 282

Parekh A. B., 1997, Physiol. Rev., 77, 10.1152/physrev.1997.77.4.901

Chen L. W., 2000, Differential regulation of Ca2+ influx by fMLP and PAF in human neutrophils:  Possible involvement of store-operated Ca2+ channel. Shock 13, 175−182

Daly J., 2000, Loperamide:  novel effects on capacitative calcium influx. Cell. Mol. Life Sci. 57, 149−157

Harper J. L., 1997, Proc. Natl. Acad. Sci. U.S.A. 94

Shin Y., 2000, Diverse effects of sphingosine on calcium mobilization and influx in differentiated HL-60 cells. Cell Calcium 27, 269−280

Hanoune J., 2001, Annu. Rev. Pharmacol. Toxicol., 41, 10.1146/annurev.pharmtox.41.1.145

Marks G. A., 2000, Infusion of adenylyl cyclase inhibitor SQ22,536 into the medial pontine reticular formation of rats enhances rapid eye movement sleep. Neuroscience 98, 311−315

Zweifach A., 1996, J. Gen. Physiol., 107, 10.1085/jgp.107.5.597

Su Z., 2001, Am. J. Physiol. Cell. Physiol., 280

Putney J. W. J., 2001, J. Cell. Sci., 114

Grafton G., 2001, Calcium channels in lymphocytes. Immunology 104, 119−126

Kerschbaum H. H., 1998, J. Gen. Physiol., 111, 10.1085/jgp.111.4.521

Guse A. H., 2001, J. Biol. Chem., 276

Lee H. C., 2000, J. Cell. Sci., 113

Schwarzmann N., 2002, J. Biol. Chem., 277, 10.1074/jbc.M209061200

Berg I., 2000, J. Cell. Biol., 150, 10.1083/jcb.150.3.581

Hoth M., 1997, J. Cell. Biol., 137, 10.1083/jcb.137.3.633

Hoth M., 2000, Proc. Natl. Acad. Sci. U.S.A. 97

Glitsch M. D., 2002, EMBO J., 21, 10.1093/emboj/cdf675

Vandecasteele G., 2001, Mitochondrial calcium homeostasis:  mechanisms and molecules. IUBMB Life 52, 213−219

Pataer A., 2003, J. Thorac. Cardiovasc. Surg., 125, 10.1016/S0022-5223(02)73247-9

Granville D. J., 2002, Sci. World J., 2, 10.1100/tsw.2002.809

Vazquez G., 2002, EMBO J., 21, 10.1093/emboj/cdf467

Ritter M., 2001, Cell. Physiol. Biochem., 11, 18, 10.1159/000047787

Rutherford P. A., 1997, Expression of Na(+)-H+ exchanger isoforms NHE1 and NHE3 in kidney and blood cells of rabbit and rat. Exp. Nephrol. 5, 490−497

Vereninov A. A., 2001, Cell. Physiol. Biochem., 11, 26, 10.1159/000047788

Stakisaitis D., 2001, Am. J. Physiol. Renal Physiol., 280, 10.1152/ajprenal.2001.280.2.F314

de la Rosa L. A., 1999, Pflugers Arch. Eur. J. Physiol., 437, 10.1007/s004240050865

Lang F., 2000, Inhibition of Jurkat-T-lymphocyte Na+/H+-exchanger by CD95(Fas/Apo-1)-receptor stimulation. Pflugers. Arch. 440, 902−907

Urcelay E., 2001, Enhanced proliferation of lymphoblasts from patients with Alzheimer dementia associated with calmodulin-dependent activation of the na+/H+ exchanger. Neurobiol. Dis. 8, 289−298

Gergely P. J., 2002, J. Immunol., 169, 10.4049/jimmunol.169.2.1092

Rothman B. L., 1993, J. Immunol., 151, 10.4049/jimmunol.151.11.6036

de la Rosa, L. A., Vilariño, N., Vieytes, M. R., and Botana, L. M. (2001) Modulation of thapsigargin-induced calcium mobilization by cyclic AMP-elevating agents in human lymphocytes is insensitive to the action of the protein kinase A inhibitor H-89.Cell. Signalling 13, 441−449.

Kaminuma O., 1999, Br. J. Pharmacol., 127, 10.1038/sj.bjp.0702558

van Tits L. J., 1991, Br. J. Pharmacol., 103, 10.1111/j.1476-5381.1991.tb09782.x

DiFrancesco D., 1991, Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature 351, 145−147

Qiu W., 2000, Am. J. Physiol. Cell. Physiol., 278

Kraus-Friedmann N., 2000, Cyclic nucleotide-gated channels in nonsensory organs. Cell Calcium 27, 127−138

Sadighi Akha A. A., 1996, J. Biol. Chem., 271

Cullen P., 2002, Nat. Rev. Mol. Cell. Biol., 3, 10.1038/nrm808

Den Dekker E., 2002, Cyclic AMP raises intracellular Ca2+ in human megakaryocytes independent of protein kinase A. Arterioscler. Thromb. Vasc. Biol. 22, 179−186

Abbreviations, azaspiracids