Effect of tramiprosate in patients with mild-to-moderate alzheimer's disease: Exploratory analyses of the MRI sub-group of the alphase study
Tóm tắt
Từ khóa
Tài liệu tham khảo
Canaveri, 2004, Toxicity of amyloid B peptide: Tales of calcium, mitochondria, and oxidative stress, Neurochem Res, 29, 637, 10.1023/B:NERE.0000014834.06405.af
Goshe, 2002, Hippocampal volume as an index of Azheimer neuropathology: findings from the Nun study, Neurology, 58, 1476, 10.1212/WNL.58.10.1476
Haroutunian, 1998, Regional distribution of neuritic plaques in the non-demented elderly and subjects with very mild Alzheimer disease, Arch. Neurol, 55, 1185, 10.1001/archneur.55.9.1185
Goshe, 2002, Hippocampal volume as an index of Azheimer neuropathology: findings from the Nun study, Neurology, 58, 1476, 10.1212/WNL.58.10.1476
Convit, 1993, Hippocampal atrophy in early Alzheimer's disease: anatomic specificity and validation, Psychiatric Quarterly, 64, 371, 10.1007/BF01064929
Csernansky, 2000, Early DAT is distinguished from aging by high-dimensional mapping of the hippocampus, Neurology, 55, 1636, 10.1212/WNL.55.11.1636
Dickerson, 2001, MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease, Neurobiology of Aging, 22, 747, 10.1016/S0197-4580(01)00271-8
Du, 2001, Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease, Journal of Neurology, Neurosurgery and Psychiatry, 71, 441, 10.1136/jnnp.71.4.441
Du, 2004, Higher Atrophy Rate of Entorhinal Cortex than Hippocampus in AD, Neurology, 62, 422, 10.1212/01.WNL.0000106462.72282.90
Krasuski, 2002, Relation of medial temporal lobe volumes to age and memory function in non-demented adults with Down's syndrome: implications for the prodromal phase of Alzheimer's disease, American Journal of Psychiatry, 159, 74, 10.1176/appi.ajp.159.1.74
Mega, 2002, Hippocampal atrophy in persons with age-associated memory impairment: volumetry within a common space, Psychosomatic Medicine, 64, 487, 10.1097/00006842-200205000-00013
Mu, 1999, A quantitative MR study of the hippocampal formation, the amygdale, and the temporal horn of the lateral ventricle in healthy subjects 40 to 90 years of age, American Journal of Neuroradiology, 20, 207
Xu, 2000, Usefulness of MRI measures of entrorhinal versus hippocampus in AD, Neurology, 14, 531
Petersen, 2000, Memory and MRI-based hippocampal volumes in aging and AD, Neurology, 54, 581, 10.1212/WNL.54.3.581
Persson, 2006, Structure-function correlates of cognitive decline in aging, Cereb Cortex, 16, 907, 10.1093/cercor/bhj036
Saykin, 2006, Older adults with cognitive complaints show brain atrophy similar to that of amnestic MCI, Neurology, 67, 834, 10.1212/01.wnl.0000234032.77541.a2
Citron, 2004, Strategies for disease modification in Alzheimer's disease, Nature Reviews, 5, 677, 10.1038/nrn1495
Gervais, 2007, Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis, Neurobiol Aging, 28, 537, 10.1016/j.neurobiolaging.2006.02.015
Krzywkowski P, Sebastiani G, Williams S, et al. Tramiprosate Prevents Amyloid Beta-induced Inhibition of Long-term Potentiation in Rat Hippocampal Slices. 8th International Conference AD/PD, Salzburg, Austria, March 14–18. 2007.
Azzi M, Morissette C, Fallon L, et al. Involvement of both GABA-dependent and — independent pathways in tramiprosate neuroprotective effects against amyloid-beta toxicity. 8th International Conference AD/PD, Salzburg, Austria, March 14–18.2007.
Aisen, 2006, A Phase II study targeting amyloid-beta with 3APS in mild-to-moderate Alzheimer disease, Neurology, 67, 1757, 10.1212/01.wnl.0000244346.08950.64
Aisen PS, Gauthier S, Ferris SH, et al. Tramiprosate in Mild to Moderate Alzheimer's Disease: a Randomized, Double-blind, Placebo-controlled, Multi-centre study (the Alphase study). Submitted.
American Psychiatric Association., 2000, 154
McKhann, 1984, Clinical Diagnosis of Alzheimer's Disease: Report of the NINCDS-ADRDA Word Group under the Auspices of Department of Health and Human Services Task Force on Alzheimer's Disease, Neurology, 34, 939, 10.1212/WNL.34.7.939
Folstein, 1975, “Mini-Mental State” A Practical Method for Grading the Cognitive State of Patients for the Clinician, J Psychiat Res, 12, 189, 10.1016/0022-3956(75)90026-6
Yesavage, 1983, Development and validation of a geriatric depression screening scale: A preliminary report, Journal of Psychiatric Research, 17, 37, 10.1016/0022-3956(82)90033-4
Singer, 1998, Using SAS PROC MIXED to fit multilevel models, hierarchical models, and individual growth models, JEBS, 24, 323
Verbeke, 2000, 568
Littell, 2006, 813
West, 2007, 353
Edwards, 2007, The efficiency of simulation-based multiple comparisons, Biometrics, 43, 913, 10.2307/2531545