Effect of poly(ADP-ribose) synthetase inhibitor administration to streptozotocin-induced diabetic rats on insulin and glucagon contents in their pancreas

Diabetes Research and Clinical Practice - Tập 3 - Trang 135-142 - 1987
Kenji Shima1, Meisei Hirota1, Mitsuyo Sato1, Satoshi Numoto2, Ichiyo Oshima1
1Department of Laboratory Medicine, Tokushima University School of Medicine, Kuramoto-cho, Tokushima 770, Japan
2Kochi City Hospital, 1-7-45, Marunouchi, Kochi 780, Japan

Tài liệu tham khảo

Stauffacher, 1970, Streptozotocin diabetes: time course of irreversible B-cell damage: further observations on prevention by nicotinamide, 133, 194 Lazarow, 1950, Protection against diabetes with nicotinamide, J. Lab. Clin. Med., 36, 249 Lazarus, 1973, Influence of nicotinamide and pyridine nucleotide on streptozotocin and alloxan-induced pancreatic B-cell cytotoxicity, Diabetes, 22, 499, 10.2337/diab.22.7.499 Rossini, 1978, Complete protection from low-dose streptozotocin-induced diabetes in mice, Nature, 276, 182, 10.1038/276182a0 Uchigata, 1983, Effect of poly(ADP-ribose) synthetase inhibitor administration to rats before and after injection of alloxan and streptozotocin on islet proinsulin synthesis, Diabetes, 32, 316, 10.2337/diabetes.32.4.316 Yonemura, 1984, Amelioration of diabetes mellitus in partially depancreatized rats by poly(ADP-ribose) synthetase inhibitors. Evidence of islet B-cell regeneration, Diabetes, 33, 401, 10.2337/diabetes.33.4.401 Yamada, 1982, Preventive and therapeutic effects of large-dose nicotinamide injections on diabetes associated with insulitis: an observation in nonobese diabetic (NOD) mice, Diabetes, 31, 749, 10.2337/diabetes.31.9.749 Yamamoto, 1981, Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets, Nature, 294, 284, 10.1038/294284a0 Yamamoto, 1981, DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin, Biochem. Biophys. Res. Commun., 103, 1014, 10.1016/0006-291X(81)90910-4 Uchigata, 1982, Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis, J. Biol. Chem., 257, 6084, 10.1016/S0021-9258(20)65108-0 Rakieten, 1971, Pancreatic islet cell tumors produced by the combined action of streptozotocin and nicotinamide, 137, 280 Kenny, 1955, Extractable glucagon of the human pancreas, J. Clin. Endocrinol. Metab., 15, 1089, 10.1210/jcem-15-9-1089 Sternberger, 1970, The unlabeled antibody-enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorse-radish peroxidase) and its use in identification of spirochetes, J. Histochem. Cytochem., 18, 315, 10.1177/18.5.315 Nishino, 1981, Glucagon radioimmunoassay with use of antiserum to glucagon C.-terminal fragment, Clin. Chem., 27, 1690, 10.1093/clinchem/27.10.1690 Nishino, 1981, Production of antisera to des-Asn28,Thr29,Homoser27-glucagon; the development of radioimmunoassay for total glucagon-like immunoreactivity in human plasma, Endocrinol Jpn., 28, 419, 10.1507/endocrj1954.28.419 Shima, 1975, Effect of an exposure to chloramine-T on the immunoreactvity of glucagon, Endocrinology, 96, 1254, 10.1210/endo-96-5-1254 Sun, 1974, A study of glucose tolerance and insulin response in partially depancreatized dogs, Diabetes, 23, 424, 10.2337/diab.23.5.424 Yasugi, 1976, Changes in carbohydrate metabolism and endocrine function of remnant pancreas after major pancreatic resection, Surgery, 132, 577, 10.1016/0002-9610(76)90346-9 Moody, 1983, Glucagon, glicentin, and related peptides, 139