Effect of peripapillary chorioretinal atrophy on GDx parameters in patients with degenerative myopia

Clinical and Experimental Ophthalmology - Tập 30 Số 6 - Trang 411-414 - 2002
Banu Bozkurt1, Murat İrkeç2, Şansal Gedik2, Mehmet Orhan2, Uğur Erdener2, Sinan Tatlıpınar2, Ergün Karaağaoğlu3
1Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey
2Departments of Ophthalmology and
3Biostatistics, Hacettepe University School of Medicine, Ankara, Turkey.

Tóm tắt

Abstract Purpose: To determine the effect of peripapillary chorio­retinal atrophy in degenerative myopia on the retinal nerve fibre layer (RNFL) thickness measurements performed by scanning laser polarimetry. Methods: Polarimetric RNFL analysis was done in 41 degenerative myopic eyes of 25 patients with spherical refractive errors between −7.50 and −22.00 D (mean −12.50 D; SD 3.5). Analysis was also performed on 46 eyes of 24 age‐matched healthy subjects with spherical refractive errors between −1.00 and +1.00 D (mean −0.25 D; SD 0.50) with GDx Nerve Fiber Analyzer (Version 1.0.12). All of the myopic patients had clinically evident peripapillary chorio­retinal atrophy in their fundus examination. Results: In myopic patients most of the GDx parameters were statistically different from the control group (P < 0.05). Although average thickness, ellipse average, number, inferior maximum and inferior average were found to be higher than the healthy subjects, the modu­lation parameters and the ratio‐based parameters were significantly decreased in degenerative myopic patients (P < 0.05). The TSNIT (temporal, superior, nasal, inferior, temporal) graph showed irregular high spikes with loss of the regular double hump pattern, especially in quadrants with large chorioretinal atrophy and visible sclera. Conclusion: Peripapillary chorioretinal atrophy increased retardation values, which might be explained by the high reflectivity of the bare sclera in these areas.

Từ khóa


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